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anti-Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 (TNFAIP8L2) Antibodies

Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Additionally we are shipping Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TNFAIP8L2 79626 Q6P589
TNFAIP8L2 69769 Q9D8Y7
TNFAIP8L2 310663 Q6AYJ8
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Top anti-Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 Antibodies at antibodies-online.com

Showing 10 out of 53 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB TNFAIP8L2 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35 µg/lane). This demonstrates the TNFAIP8L2 antibody detected the TNFAIP8L2 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Mouse Rabbit Un-conjugated WB TNFAIP8L2 Antibody (N-term) (ABIN655292) western blot analysis in mouse heart tissue lysates (35 µg/lane). This demonstrates the TNFAIP8L2 antibody detected the TNFAIP8L2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Mouse Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated WB   400 μL Log in to see 8 to 10 Days
$463.83
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated WB   200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 11 to 16 Days
$412.86
Details
Mouse Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details

TNFAIP8L2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 Antibodies

  1. Human Polyclonal TNFAIP8L2 Primary Antibody for EIA, WB - ABIN955273 : Zhang, Hao, Lou, Xi, Wang, Wang, Qu, Guo, Chen, Zhang, Liu: Tissue-specific expression of TIPE2 provides insights into its function. in Molecular immunology 2010 (PubMed)

  2. Human Polyclonal TNFAIP8L2 Primary Antibody for ELISA, WB - ABIN1450851 : Sun, Gong, Carmody, Hilliard, Li, Sun, Kong, Xu, Hilliard, Hu, Shen, Yang, Chen: TIPE2, a negative regulator of innate and adaptive immunity that maintains immune homeostasis. in Cell 2008 (PubMed)

More Antibodies against Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 Interaction Partners

Human Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 (TNFAIP8L2) interaction partners

  1. The TIPE2-elicited antimetastatic effect in gastric cancer was closely associated with the inhibition of AKT signaling and enhancement of GSK3b activity followed by the degradation and decreased translocation to nucleus of b-catenin

  2. TIPE2 promoted lung cancer cell apoptosis through affecting apoptosis-related molecules caspase-3 (show CASP3 Antibodies), caspase-9 (show CASP9 Antibodies), Bcl-2 (show BCL2 Antibodies) and Bax (show BAX Antibodies), possibly via regulating P38 (show CRK Antibodies) and Akt (show AKT1 Antibodies) pathways.

  3. Tumor necrosis factor-alpha-induced protein-8 like-2 (TIPE2) upregulates p27 (show PAK2 Antibodies) to decrease gastic cancer cell proliferation

  4. TIPE2 mRNA showed sensitivity of 74.63%, specificity of 90.24%, positive predictive value of 92.5%, and negative predictive value of 67.3% for predicting 3-month mortality in Acute-on-Chronic Hepatitis B Liver Failure.

  5. These results strongly suggest that TIPE2 plays an important role in shifting L-arginase (show ARG1 Antibodies) metabolism from production of NO to urea, during host inflammatory response.

  6. Both TNF-alpha (show TNF Antibodies) and TIPE2 might be potential targets for the treatment of hepatocellular carcinoma metastasis.

  7. TIPE2 might serve as a tumor suppressor in non-small cell lung cancer progression.

  8. TIPE2 can inhibit caspase-8 (show CASP8 Antibodies) activity in colon cancer cells. TIPE2 can regulate TLR4 (show TLR4 Antibodies) inflammatory effect and inhibit further amplification of cascade reaction via caspase-8 (show CASP8 Antibodies).

  9. TIPE2 plays an important role in regulating hepatitis B virus-specific CD8 (show CD8A Antibodies)(+) T cell functions in patients with hepatitis B.

  10. Human TIPE2 is an endogenous inhibitor of Rac1 in hepatocellular carcinoma (HCC (show FAM126A Antibodies)) by which it attenuates invasion and metastasis of HCC (show FAM126A Antibodies).

Mouse (Murine) Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 (TNFAIP8L2) interaction partners

  1. TIPE2 acts as a negative regulator linking NOD2 (show NOD2 Antibodies) and inflammatory responses.

  2. TIPE2 plays a suppressive role in injury-induced restenosis and may serve as a new therapeutic target for treating the disease.

  3. Tipe2 provides a molecular bridge between miR (show MLXIP Antibodies)-21 and cell apoptosis; miR (show MLXIP Antibodies)-21 suppresses apoptosis in activated T cells at least in part through directly targeting tumor suppressor gene Tipe2.

  4. TIPE2 deficiency in hematopoietic cells ameliorates experimental colitis; TIPE2 is a negative regulator of antibacterial immunity, indicating that TIPE2 promotes colitis by inhibiting mucosal immunity to commensal bacteria.

  5. TIPE2 plays a crucial atheroprotective role likely by regulating macrophage responses to oxidized low-density lipoprotein.

  6. study reports that TIPE2, the tumor necrosis factor-alpha-induced protein 8-like 2, plays an atheroprotective role by regulating phenotypic switching of vascular smooth muscle cells in response to oxidized low-density lipoprotein stimuli

  7. TIPE2 protein serves as a negative regulator of phagocytosis and oxidative burst during infection

  8. TIPE2 plays an essential role in a signal transduction pathway that links the inflammatory immune response to specific conditions after cerebral ischemia.

  9. TIPE2 regulates polyinosinic-polycytidylic acid [poly I:C]-induced innate immune responses by targeting Rac (show AKT1 Antibodies) GTPase (show RACGAP1 Antibodies) pathways in a phosphatidylinositol 3-kinase (PI3K)-dependent manner.

  10. The results suggested that TIPE2 appeared to be a critical immunoregulatory molecule involved in immunosuppressive function of CD4 (show CD4 Antibodies)(+)CD25 (show IL2RA Antibodies)(+) Tregs.

Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 (TNFAIP8L2) Antigen Profile

Protein Summary

Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits jun/ap1 and NF-kappa-B activation. Promotes Fas-induced apoptosis (By similarity).

Gene names and symbols associated with TNFAIP8L2

  • tumor necrosis factor, alpha-induced protein 8-like 2 (TNFAIP8L2) antibody
  • tumor necrosis factor, alpha-induced protein 8-like 2 (Tnfaip8l2) antibody
  • tumor necrosis factor, alpha-induced protein 8-like 2 (tnfaip8l2-a) antibody
  • Tumor necrosis factor, alpha-induced protein 8-like protein 2 (tp8l2) antibody
  • 1810019A08Rik antibody
  • AW610835 antibody
  • RGD1310519 antibody
  • TIPE2 antibody
  • tnfaip8l2 antibody

Protein level used designations for TNFAIP8L2

TNF alpha-induced protein 8-like protein 2 , TNFAIP8-like protein 2 , inflammation factor 20 , inflammation factor protein 20 , tumor necrosis factor alpha-induced protein 8-like protein 2 , tumor necrosis factor, alpha-induced protein 8-like protein 2 , TIPE2 , Tumor necrosis factor, alpha-induced protein 8-like protein 2 , tumor necrosis factor, alpha-induced protein 8-like protein 2 a

GENE ID SPECIES
79626 Homo sapiens
69769 Mus musculus
310663 Rattus norvegicus
510652 Bos taurus
100328663 Oryctolagus cuniculus
399018 Xenopus laevis
100195718 Salmo salar
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