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Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 (TNFAIP8L2) ELISA Kits

Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Additionally we are shipping Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 Antibodies (53) and Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human TNFAIP8L2 TNFAIP8L2 79626 Q6P589
Anti-Mouse TNFAIP8L2 TNFAIP8L2 69769 Q9D8Y7
Anti-Rat TNFAIP8L2 TNFAIP8L2 310663 Q6AYJ8
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More ELISA Kits for Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 Interaction Partners

Human Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 (TNFAIP8L2) interaction partners

  1. The TIPE2-elicited antimetastatic effect in gastric cancer was closely associated with the inhibition of AKT signaling and enhancement of GSK3b activity followed by the degradation and decreased translocation to nucleus of b-catenin

  2. TIPE2 promoted lung cancer cell apoptosis through affecting apoptosis-related molecules caspase-3 (show CASP3 ELISA Kits), caspase-9 (show CASP9 ELISA Kits), Bcl-2 (show BCL2 ELISA Kits) and Bax (show BAX ELISA Kits), possibly via regulating P38 (show CRK ELISA Kits) and Akt (show AKT1 ELISA Kits) pathways.

  3. Tumor necrosis factor-alpha-induced protein-8 like-2 (TIPE2) upregulates p27 (show PAK2 ELISA Kits) to decrease gastic cancer cell proliferation

  4. TIPE2 mRNA showed sensitivity of 74.63%, specificity of 90.24%, positive predictive value of 92.5%, and negative predictive value of 67.3% for predicting 3-month mortality in Acute-on-Chronic Hepatitis B Liver Failure.

  5. These results strongly suggest that TIPE2 plays an important role in shifting L-arginase (show ARG1 ELISA Kits) metabolism from production of NO to urea, during host inflammatory response.

  6. Both TNF-alpha (show TNF ELISA Kits) and TIPE2 might be potential targets for the treatment of hepatocellular carcinoma metastasis.

  7. TIPE2 might serve as a tumor suppressor in non-small cell lung cancer progression.

  8. TIPE2 can inhibit caspase-8 (show CASP8 ELISA Kits) activity in colon cancer cells. TIPE2 can regulate TLR4 (show TLR4 ELISA Kits) inflammatory effect and inhibit further amplification of cascade reaction via caspase-8 (show CASP8 ELISA Kits).

  9. TIPE2 plays an important role in regulating hepatitis B virus-specific CD8 (show CD8A ELISA Kits)(+) T cell functions in patients with hepatitis B.

  10. Human TIPE2 is an endogenous inhibitor of Rac1 in hepatocellular carcinoma (HCC (show FAM126A ELISA Kits)) by which it attenuates invasion and metastasis of HCC (show FAM126A ELISA Kits).

Mouse (Murine) Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 (TNFAIP8L2) interaction partners

  1. TIPE2 alleviates experimental SLE through induction of macrophage polarization to a M2 phenotype, which may be used as a promising therapeutic strategy for treating SLE.

  2. TIPE2 acts as a negative regulator linking NOD2 (show NOD2 ELISA Kits) and inflammatory responses.

  3. TIPE2 plays a suppressive role in injury-induced restenosis and may serve as a new therapeutic target for treating the disease.

  4. Tipe2 provides a molecular bridge between miR (show MLXIP ELISA Kits)-21 and cell apoptosis; miR (show MLXIP ELISA Kits)-21 suppresses apoptosis in activated T cells at least in part through directly targeting tumor suppressor gene Tipe2.

  5. TIPE2 deficiency in hematopoietic cells ameliorates experimental colitis; TIPE2 is a negative regulator of antibacterial immunity, indicating that TIPE2 promotes colitis by inhibiting mucosal immunity to commensal bacteria.

  6. TIPE2 plays a crucial atheroprotective role likely by regulating macrophage responses to oxidized low-density lipoprotein.

  7. study reports that TIPE2, the tumor necrosis factor-alpha-induced protein 8-like 2, plays an atheroprotective role by regulating phenotypic switching of vascular smooth muscle cells in response to oxidized low-density lipoprotein stimuli

  8. TIPE2 protein serves as a negative regulator of phagocytosis and oxidative burst during infection

  9. TIPE2 plays an essential role in a signal transduction pathway that links the inflammatory immune response to specific conditions after cerebral ischemia.

  10. TIPE2 regulates polyinosinic-polycytidylic acid [poly I:C]-induced innate immune responses by targeting Rac (show AKT1 ELISA Kits) GTPase (show RACGAP1 ELISA Kits) pathways in a phosphatidylinositol 3-kinase (PI3K)-dependent manner.

Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 (TNFAIP8L2) Antigen Profile

Antigen Summary

Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits jun/ap1 and NF-kappa-B activation. Promotes Fas-induced apoptosis (By similarity).

Gene names and symbols associated with TNFAIP8L2

  • tumor necrosis factor, alpha-induced protein 8-like 2 (TNFAIP8L2) antibody
  • tumor necrosis factor, alpha-induced protein 8-like 2 (Tnfaip8l2) antibody
  • tumor necrosis factor, alpha-induced protein 8-like 2 (tnfaip8l2-a) antibody
  • Tumor necrosis factor, alpha-induced protein 8-like protein 2 (tp8l2) antibody
  • 1810019A08Rik antibody
  • AW610835 antibody
  • RGD1310519 antibody
  • TIPE2 antibody
  • tnfaip8l2 antibody

Protein level used designations for TNFAIP8L2

TNF alpha-induced protein 8-like protein 2 , TNFAIP8-like protein 2 , inflammation factor 20 , inflammation factor protein 20 , tumor necrosis factor alpha-induced protein 8-like protein 2 , tumor necrosis factor, alpha-induced protein 8-like protein 2 , TIPE2 , Tumor necrosis factor, alpha-induced protein 8-like protein 2 , tumor necrosis factor, alpha-induced protein 8-like protein 2 a

GENE ID SPECIES
79626 Homo sapiens
69769 Mus musculus
310663 Rattus norvegicus
510652 Bos taurus
100328663 Oryctolagus cuniculus
399018 Xenopus laevis
100195718 Salmo salar
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