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Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 (TNFAIP8L2) ELISA Kits

Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Additionally we are shipping Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 Antibodies (53) and Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human TNFAIP8L2 TNFAIP8L2 79626 Q6P589
Anti-Mouse TNFAIP8L2 TNFAIP8L2 69769 Q9D8Y7
Anti-Rat TNFAIP8L2 TNFAIP8L2 310663 Q6AYJ8
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More ELISA Kits for Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 Interaction Partners

Human Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 (TNFAIP8L2) interaction partners

  1. Results provide evidence that TIPE2 acts as an inhibitor of gastric cancer cell growth and triggers an IRF4 (show IRF4 ELISA Kits)-associated signaling cascade that promotes p27 (show PAK2 ELISA Kits) expression and restores control of cell proliferation.

  2. The TIPE2-elicited antimetastatic effect in gastric cancer was closely associated with the inhibition of AKT signaling and enhancement of GSK3b activity followed by the degradation and decreased translocation to nucleus of b-catenin

  3. TIPE2 promoted lung cancer cell apoptosis through affecting apoptosis-related molecules caspase-3 (show CASP3 ELISA Kits), caspase-9 (show CASP9 ELISA Kits), Bcl-2 (show BCL2 ELISA Kits) and Bax (show BAX ELISA Kits), possibly via regulating P38 (show CRK ELISA Kits) and Akt (show AKT1 ELISA Kits) pathways.

  4. Tumor necrosis factor-alpha-induced protein-8 like-2 (TIPE2) upregulates p27 (show PAK2 ELISA Kits) to decrease gastic cancer cell proliferation

  5. TIPE2 mRNA showed sensitivity of 74.63%, specificity of 90.24%, positive predictive value of 92.5%, and negative predictive value of 67.3% for predicting 3-month mortality in Acute-on-Chronic Hepatitis B Liver Failure.

  6. These results strongly suggest that TIPE2 plays an important role in shifting L-arginase (show ARG1 ELISA Kits) metabolism from production of NO to urea, during host inflammatory response.

  7. Both TNF-alpha (show TNF ELISA Kits) and TIPE2 might be potential targets for the treatment of hepatocellular carcinoma metastasis.

  8. TIPE2 might serve as a tumor suppressor in non-small cell lung cancer progression.

  9. TIPE2 can inhibit caspase-8 (show CASP8 ELISA Kits) activity in colon cancer cells. TIPE2 can regulate TLR4 (show TLR4 ELISA Kits) inflammatory effect and inhibit further amplification of cascade reaction via caspase-8 (show CASP8 ELISA Kits).

  10. TIPE2 plays an important role in regulating hepatitis B virus-specific CD8 (show CD8A ELISA Kits)(+) T cell functions in patients with hepatitis B.

Mouse (Murine) Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 (TNFAIP8L2) interaction partners

  1. Data show that after tumor necrosis factor alpha-induced protein 8 like-2 (TIPE2) gene was down-regulated, the expression of the CD69 antigen (show CD69 ELISA Kits) was increased, and the proliferation of T lymphocytes and the secretion of cytokines IL-2 (show IL2 ELISA Kits) and IFN-gamma (show IFNG ELISA Kits) were enhanced.

  2. TIPE2 alleviates experimental SLE through induction of macrophage polarization to a M2 phenotype, which may be used as a promising therapeutic strategy for treating SLE.

  3. TIPE2 acts as a negative regulator linking NOD2 (show NOD2 ELISA Kits) and inflammatory responses.

  4. TIPE2 plays a suppressive role in injury-induced restenosis and may serve as a new therapeutic target for treating the disease.

  5. Tipe2 provides a molecular bridge between miR (show MLXIP ELISA Kits)-21 and cell apoptosis; miR (show MLXIP ELISA Kits)-21 suppresses apoptosis in activated T cells at least in part through directly targeting tumor suppressor gene Tipe2.

  6. TIPE2 deficiency in hematopoietic cells ameliorates experimental colitis; TIPE2 is a negative regulator of antibacterial immunity, indicating that TIPE2 promotes colitis by inhibiting mucosal immunity to commensal bacteria.

  7. TIPE2 plays a crucial atheroprotective role likely by regulating macrophage responses to oxidized low-density lipoprotein.

  8. study reports that TIPE2, the tumor necrosis factor-alpha-induced protein 8-like 2, plays an atheroprotective role by regulating phenotypic switching of vascular smooth muscle cells in response to oxidized low-density lipoprotein stimuli

  9. TIPE2 protein serves as a negative regulator of phagocytosis and oxidative burst during infection

  10. TIPE2 plays an essential role in a signal transduction pathway that links the inflammatory immune response to specific conditions after cerebral ischemia.

Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 (TNFAIP8L2) Antigen Profile

Antigen Summary

Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits jun/ap1 and NF-kappa-B activation. Promotes Fas-induced apoptosis (By similarity).

Gene names and symbols associated with TNFAIP8L2

  • tumor necrosis factor, alpha-induced protein 8-like 2 (TNFAIP8L2) antibody
  • tumor necrosis factor, alpha-induced protein 8-like 2 (Tnfaip8l2) antibody
  • tumor necrosis factor, alpha-induced protein 8-like 2 (tnfaip8l2-a) antibody
  • Tumor necrosis factor, alpha-induced protein 8-like protein 2 (tp8l2) antibody
  • 1810019A08Rik antibody
  • AW610835 antibody
  • RGD1310519 antibody
  • TIPE2 antibody
  • tnfaip8l2 antibody

Protein level used designations for TNFAIP8L2

TNF alpha-induced protein 8-like protein 2 , TNFAIP8-like protein 2 , inflammation factor 20 , inflammation factor protein 20 , tumor necrosis factor alpha-induced protein 8-like protein 2 , tumor necrosis factor, alpha-induced protein 8-like protein 2 , TIPE2 , Tumor necrosis factor, alpha-induced protein 8-like protein 2 , tumor necrosis factor, alpha-induced protein 8-like protein 2 a

GENE ID SPECIES
79626 Homo sapiens
69769 Mus musculus
310663 Rattus norvegicus
510652 Bos taurus
100328663 Oryctolagus cuniculus
399018 Xenopus laevis
100195718 Salmo salar
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