Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 (TNFAIP8L2) ELISA Kits

Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Additionally we are shipping Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 Antibodies (55) and Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human TNFAIP8L2 TNFAIP8L2 79626 Q6P589
Anti-Mouse TNFAIP8L2 TNFAIP8L2 69769 Q9D8Y7
Anti-Rat TNFAIP8L2 TNFAIP8L2 310663 Q6AYJ8
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More ELISA Kits for Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 Interaction Partners

Human Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 (TNFAIP8L2) interaction partners

  1. the expression of TIPE2 protein could be a predictor of better prognosis for DLBCL.

  2. Insufficient expression of TIPE2 might be involved in the hyperreactivity of monocyte to Toll (show TLR4 ELISA Kits)-like receptor ligands in primary biliary cirrhosis.

  3. data provided the first evidence that TIPE2 inhibits gastric cancer cell migration, invasion and metastasis very probably via reversal of EMT (show ITK ELISA Kits), revealing that TIPE2 may be a novel therapeutic target for human gastric cancer EMT (show ITK ELISA Kits) and metastasis.

  4. Authors demonstrated that TIPE2 overexpression may suppress proliferation, migration, and invasion in prostate cancer cells by inhibiting the PI3K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits) signaling pathway.

  5. TIPE2 suppressed breast cancer tumorigenesis, growth and metastasis possibly via regulation of the AKT (show AKT1 ELISA Kits) and p38 (show CRK ELISA Kits) signaling pathways.

  6. these data suggest that TIPE2 overexpression inhibited hypoxia-induced Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) pathway activation and EMT (show ITK ELISA Kits) in glioma cells.

  7. this study shows that TIPE2 contributes to the pathogenesis of ankylosing spondylitis

  8. TIPE2 expression was significantly decreased in human breast cancer tissue and cell lines. Overexpression of TIPE2 inhibited the proliferation in vitro and tumor xenograft growth in vivo. TIPE2 also inhibited the migration/invasion of breast cancer cells through preventing the epithelial-to-mesenchymal transition (EMT (show ITK ELISA Kits)) phenotype.

  9. Low expression of TIPE2 is associated with hepatocellular carcinogenesis.

  10. our data suggest a previously unappreciated role of TIPE2 in the crosstalk between skin SCC (show CYP11A1 ELISA Kits) and TAMs and highlight TIPE2 as a promising novel target for skin SCC (show CYP11A1 ELISA Kits) treatment.

Mouse (Murine) Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 (TNFAIP8L2) interaction partners

  1. TIPE2 inhibited breast cancer development and metastasis possibly via promoting CD8 (show CD8A ELISA Kits)(+) T and NK cell-mediated antitumor immune responses

  2. Our current study shows that TIPE2-deficient bone-marrow cells are defective in IL-4 (show IL4 ELISA Kits) induced M2 macrophage differentiation in vitro. TIPE2 promotes phosphoinositide metabolism and the activation of the down-stream AKT (show AKT1 ELISA Kits) signaling pathway, which in turn leads to the expression of markers specific for M2 macrophages.

  3. The present study demonstrates that TIPE2 acts as a novel negative regulator of inflammatory and immune responses through TAK1 (show NR2C2 ELISA Kits) signaling.

  4. Data show that after tumor necrosis factor alpha-induced protein 8 like-2 (TIPE2) gene was down-regulated, the expression of the CD69 antigen (show CD69 ELISA Kits) was increased, and the proliferation of T lymphocytes and the secretion of cytokines IL-2 (show IL2 ELISA Kits) and IFN-gamma (show IFNG ELISA Kits) were enhanced.

  5. TIPE2 alleviates experimental SLE through induction of macrophage polarization to a M2 phenotype, which may be used as a promising therapeutic strategy for treating SLE.

  6. TIPE2 acts as a negative regulator linking NOD2 (show NOD2 ELISA Kits) and inflammatory responses.

  7. TIPE2 plays a suppressive role in injury-induced restenosis and may serve as a new therapeutic target for treating the disease.

  8. Tipe2 provides a molecular bridge between miR (show MLXIP ELISA Kits)-21 and cell apoptosis; miR (show MLXIP ELISA Kits)-21 suppresses apoptosis in activated T cells at least in part through directly targeting tumor suppressor gene Tipe2.

  9. TIPE2 deficiency in hematopoietic cells ameliorates experimental colitis; TIPE2 is a negative regulator of antibacterial immunity, indicating that TIPE2 promotes colitis by inhibiting mucosal immunity to commensal bacteria.

  10. TIPE2 plays a crucial atheroprotective role likely by regulating macrophage responses to oxidized low-density lipoprotein.

Tumor Necrosis Factor, alpha-Induced Protein 8-Like 2 (TNFAIP8L2) Antigen Profile

Antigen Summary

Acts as a negative regulator of innate and adaptive immunity by maintaining immune homeostasis. Negative regulator of Toll-like receptor and T-cell receptor function. Prevents hyperresponsiveness of the immune system and maintains immune homeostasis. Inhibits jun/ap1 and NF-kappa-B activation. Promotes Fas-induced apoptosis (By similarity).

Gene names and symbols associated with TNFAIP8L2

  • tumor necrosis factor, alpha-induced protein 8-like 2 (TNFAIP8L2) antibody
  • tumor necrosis factor, alpha-induced protein 8-like 2 (Tnfaip8l2) antibody
  • tumor necrosis factor, alpha-induced protein 8-like 2 (tnfaip8l2-a) antibody
  • Tumor necrosis factor, alpha-induced protein 8-like protein 2 (tp8l2) antibody
  • 1810019A08Rik antibody
  • AW610835 antibody
  • RGD1310519 antibody
  • TIPE2 antibody
  • tnfaip8l2 antibody

Protein level used designations for TNFAIP8L2

TNF alpha-induced protein 8-like protein 2 , TNFAIP8-like protein 2 , inflammation factor 20 , inflammation factor protein 20 , tumor necrosis factor alpha-induced protein 8-like protein 2 , tumor necrosis factor, alpha-induced protein 8-like protein 2 , TIPE2 , Tumor necrosis factor, alpha-induced protein 8-like protein 2 , tumor necrosis factor, alpha-induced protein 8-like protein 2 a

GENE ID SPECIES
79626 Homo sapiens
69769 Mus musculus
310663 Rattus norvegicus
510652 Bos taurus
100328663 Oryctolagus cuniculus
399018 Xenopus laevis
100195718 Salmo salar
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