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The protein encoded by TNFSF13 is a member of the tumor necrosis factor (TNF) ligand family. Additionally we are shipping Tumor Necrosis Factor (Ligand) Superfamily, Member 13 Kits (42) and Tumor Necrosis Factor (Ligand) Superfamily, Member 13 Proteins (34) and many more products for this protein.
Showing 10 out of 158 products:
Human Polyclonal TNFSF13 Primary Antibody for EIA, IHC (p) - ABIN499325
Gross, Johnston, Mudri, Enselman, Dillon, Madden, Xu, Parrish-Novak, Foster, Lofton-Day, Moore, Littau, Grossman, Haugen, Foley, Blumberg, Harrison, Kindsvogel, Clegg: TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease. in Nature 2000
Show all 9 references for ABIN499325
Human Polyclonal TNFSF13 Primary Antibody for EIA, WB - ABIN499323
Yu, Boone, Delaney, Hawkins, Kelley, Ramakrishnan, McCabe, Qiu, Kornuc, Xia, Guo, Stolina, Boyle, Sarosi, Hsu, Senaldi, Theill: APRIL and TALL-I and receptors BCMA and TACI: system for regulating humoral immunity. in Nature immunology 2001
Show all 4 references for ABIN499323
Mouse (Murine) Monoclonal TNFSF13 Primary Antibody for FACS - ABIN2663230
Benson, Dillon, Castigli, Geha, Xu, Lam, Noelle: Cutting edge: the dependence of plasma cells and independence of memory B cells on BAFF and APRIL. in Journal of immunology (Baltimore, Md. : 1950) 2008
Show all 3 references for ABIN2663230
Human Monoclonal TNFSF13 Primary Antibody for ELISA, WB - ABIN563762
Guadagnoli, Kimberley, Phan, Cameron, Vink, Rodermond, Eldering, Kater, van Eenennaam, Medema: Development and characterization of APRIL antagonistic monoclonal antibodies for treatment of B-cell lymphomas. in Blood 2011
Host-derived proteins pp32 and APRIL interact with a free form of influenza virus RNA-dependent RNA polymerase and preferentially upregulates viral RNA synthesis rather than cRNA synthesis.
high expression of APRIL in clear cell renal cell carcinoma (show MOK Antibodies) was correlated with high Fuhrman nuclear grade, high pathologic stage, and poor overall and cancer-specific survival of the patients
TNFSF13 and FDX1 have potential roles in IgAN in the Han Chinese population. This information may be useful in the development of early prognostics for IgAN.
Did not find any positive association between TNFSF13 SNPs and the risk of IgA nephropathy after adjustment for age and sex, but did find a significant and strong correlation with relevant clinical pathological parameters.
plasma level elevated in IgA nephropathy
results indicate that analysis of serum concentrations of BAFF (show TNFSF13B Antibodies) and APRIL potentially represents a useful tool for the assessment of AIHA disease activity and progression.
Abnormal levels of BAFF (show TNFSF13B Antibodies)/APRIL in pediatric acute lymphoblastic leukemia suggest that BAFF (show TNFSF13B Antibodies)/APRIL are associated with the development and progression of this disease in children
SNPs rs9514828 (BAFF (show TNFSF13B Antibodies)), rs3803800 (APRIL) and rs4985726 (TACI (show TNFRSF13B Antibodies)) may be associated with the risk of development of B-cell chronic lymphocytic leukemia in a Polish population.
the elevated presence of APRIL and BLyS (show TNFSF13B Antibodies) in B cell-rich areas of chronically inflamed gingiva suggests that these cytokines may contribute to bone loss by promoting the survival and persistence of RANKL (show TNFSF11 Antibodies)-expressing B cells/plasma cells.
Results show that APRIL was significantly up-regulated in gastric cancer and high levels of APRIL correlated with resistance to cisplatin through the activation of the canonical NF-kappaB (show NFKB1 Antibodies) pathway.
this is the first study to implicate the APRIL signal transduction pathway in the pathogenesis of nephrogenic IgA production. Moreover, our findings identify APRIL as a potential target of therapy.
B cell activating factor (BAFF (show TNFSF13B Antibodies)) and a proliferation inducing ligand (APRIL) mediate CD40 (show CD40 Antibodies)-independent help by memory CD4 (show CD4 Antibodies) T cells in transplantations.
Heteromers consisting of one BAFF (show TNFSF13B Antibodies) and two APRIL bind to receptor TACI (show TNFRSF13B Antibodies), BCMA (show TNFRSF17 Antibodies) but not to BAFFR (show TNFRSF13C Antibodies).
Immunization of mice with a DNA vaccine encoding BAFF (show TNFSF13B Antibodies) or APRIL multitrimers, together with interleukin 12 and membrane-bound HIV-1 Env (show ERVW-1 Antibodies) gp140, induced neutralizing antibodies against tier 1 and tier 2 (vaccine strain) viruses.
APRIL selectively enhances axonal growth by activating ERK (show EPHB2 Antibodies) signaling and PI3-kinase (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies)/GSK-3beta (show GSK3b Antibodies) signaling.
Data indicate that APRIL expression accelerates the onset of TCL1 (show TCL1A Antibodies)-driven leukemia formation mainly through TACI (show TNFRSF13B Antibodies) activation.
The ability of TACI (show TNFRSF13B Antibodies)-Fc to activate reverse signalling through BAFF (show TNFSF13B Antibodies) and APRIL, was investigated.
CD1d (show CD1D Antibodies)-restricted invariant NKT (show CTSL1 Antibodies) cell-derived BAFF (show TNFSF13B Antibodies) and APRIL each contribute to survival of plasma cells induced by immunization.
The TNF (show TNF Antibodies) family member APRIL dampens collagen-induced arthritis.
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified\; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.
tumor necrosis factor ligand superfamily member 13
, tumor necrosis factor ligand superfamily member 13 isoform alpha proprotein
, SLAN protein
, Acidic leucine-rich nuclear phosphoprotein 32 family member B
, TNF superfamily member 13
, TNFSF12-TNFSF13 readthrough transcript
, tumor necrosis factor superfamily member 13
, tumor necrosis factor (ligand) superfamily, member 13
, TNF- and APOL-related leukocyte expressed ligand 2
, a proliferation-inducing ligand
, tumor necrosis factor-like protein ZTNF2
, tumor necrosis factor-related death ligand-1
, A proliferation-inducing ligand