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Tumor Necrosis Factor (Ligand) Superfamily, Member 13 Proteins (TNFSF13)

The protein encoded by TNFSF13 is a member of the tumor necrosis factor (TNF) ligand family. Additionally we are shipping Tumor Necrosis Factor (Ligand) Superfamily, Member 13 Antibodies (158) and Tumor Necrosis Factor (Ligand) Superfamily, Member 13 Kits (42) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TNFSF13 8741 O75888
TNFSF13 69583 Q9D777
TNFSF13 287437  
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Top Tumor Necrosis Factor (Ligand) Superfamily, Member 13 Proteins at antibodies-online.com

Showing 10 out of 36 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 4 pack Log in to see 10 to 12 Days
$86.96
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_HEK293 Human DYKDDDDK Tag   10 μg Log in to see 5 to 8 Days
$351.75
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   50 μg Log in to see 2 to 3 Days
$630.00
Details
HOST_Hi-5 Cells Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$1,233.75
Details
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 11 to 13 Days
$809.60
Details
HOST_Escherichia coli (E. coli) Rhesus Monkey His tag 100 μg Log in to see 11 to 13 Days
$932.80
Details
HOST_Human Cells Mouse Fc Tag 50 μg Log in to see 16 Days
$272.80
Details

TNFSF13 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
, ,
Mouse (Murine) , ,
, ,
Rat (Rattus)

Top referenced Tumor Necrosis Factor (Ligand) Superfamily, Member 13 Proteins

  1. Human TNFSF13 Protein expressed in Escherichia coli (E. coli) - ABIN2667376 : Bossen, Ingold, Tardivel, Bodmer, Gaide, Hertig, Ambrose, Tschopp, Schneider: Interactions of tumor necrosis factor (TNF) and TNF receptor family members in the mouse and human. in The Journal of biological chemistry 2006 (PubMed)
    Show all 13 references for ABIN2667376

  2. Human TNFSF13 Protein expressed in HEK293 - ABIN1344412 : Litinskiy, Nardelli, Hilbert, He, Schaffer, Casali, Cerutti: DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL. in Nature immunology 2002 (PubMed)
    Show all 9 references for ABIN1344412

  3. Human TNFSF13 Protein expressed in Wheat germ - ABIN1323221 : Chihara, Aranami, Sato, Miyazaki, Miyake, Okamoto, Ogawa, Toda, Yamamura: Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica. in Proceedings of the National Academy of Sciences of the United States of America 2011 (PubMed)

More Proteins for Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13) Interaction Partners

Human Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13) interaction partners

  1. Host-derived proteins pp32 and APRIL interact with a free form of influenza virus RNA-dependent RNA polymerase and preferentially upregulates viral RNA synthesis rather than cRNA synthesis.

  2. high expression of APRIL in clear cell renal cell carcinoma (show MOK Proteins) was correlated with high Fuhrman nuclear grade, high pathologic stage, and poor overall and cancer-specific survival of the patients

  3. TNFSF13 and FDX1 have potential roles in IgAN in the Han Chinese population. This information may be useful in the development of early prognostics for IgAN.

  4. Did not find any positive association between TNFSF13 SNPs and the risk of IgA nephropathy after adjustment for age and sex, but did find a significant and strong correlation with relevant clinical pathological parameters.

  5. plasma level elevated in IgA nephropathy

  6. results indicate that analysis of serum concentrations of BAFF (show TNFSF13B Proteins) and APRIL potentially represents a useful tool for the assessment of AIHA disease activity and progression.

  7. Abnormal levels of BAFF (show TNFSF13B Proteins)/APRIL in pediatric acute lymphoblastic leukemia suggest that BAFF (show TNFSF13B Proteins)/APRIL are associated with the development and progression of this disease in children

  8. SNPs rs9514828 (BAFF (show TNFSF13B Proteins)), rs3803800 (APRIL) and rs4985726 (TACI (show TNFRSF13B Proteins)) may be associated with the risk of development of B-cell chronic lymphocytic leukemia in a Polish population.

  9. the elevated presence of APRIL and BLyS (show TNFSF13B Proteins) in B cell-rich areas of chronically inflamed gingiva suggests that these cytokines may contribute to bone loss by promoting the survival and persistence of RANKL (show TNFSF11 Proteins)-expressing B cells/plasma cells.

  10. Results show that APRIL was significantly up-regulated in gastric cancer and high levels of APRIL correlated with resistance to cisplatin through the activation of the canonical NF-kappaB (show NFKB1 Proteins) pathway.

Mouse (Murine) Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13) interaction partners

  1. this is the first study to implicate the APRIL signal transduction pathway in the pathogenesis of nephrogenic IgA production. Moreover, our findings identify APRIL as a potential target of therapy.

  2. the elevated presence of APRIL and BLyS (show TNFSF13B Proteins) in B cell-rich areas of chronically inflamed gingiva suggests that these cytokines may contribute to bone loss by promoting the survival and persistence of RANKL (show TNFSF11 Proteins)-expressing B cells/plasma cells.

  3. B cell activating factor (BAFF (show TNFSF13B Proteins)) and a proliferation inducing ligand (APRIL) mediate CD40 (show CD40 Proteins)-independent help by memory CD4 (show CD4 Proteins) T cells in transplantations.

  4. Heteromers consisting of one BAFF (show TNFSF13B Proteins) and two APRIL bind to receptor TACI (show TNFRSF13B Proteins), BCMA (show TNFRSF17 Proteins) but not to BAFFR (show TNFRSF13C Proteins).

  5. Immunization of mice with a DNA vaccine encoding BAFF (show TNFSF13B Proteins) or APRIL multitrimers, together with interleukin 12 and membrane-bound HIV-1 Env (show ERVW-1 Proteins) gp140, induced neutralizing antibodies against tier 1 and tier 2 (vaccine strain) viruses.

  6. APRIL selectively enhances axonal growth by activating ERK signaling and PI3-kinase/Akt/GSK-3beta signaling.

  7. Data indicate that APRIL expression accelerates the onset of TCL1 (show TCL1A Proteins)-driven leukemia formation mainly through TACI (show TNFRSF13B Proteins) activation.

  8. The ability of TACI (show TNFRSF13B Proteins)-Fc to activate reverse signalling through BAFF (show TNFSF13B Proteins) and APRIL, was investigated.

  9. CD1d (show CD1D Proteins)-restricted invariant NKT (show CTSL1 Proteins) cell-derived BAFF (show TNFSF13B Proteins) and APRIL each contribute to survival of plasma cells induced by immunization.

  10. The TNF (show TNF Proteins) family member APRIL dampens collagen-induced arthritis.

Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified\; such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13.

Gene names and symbols associated with TNFSF13

  • tumor necrosis factor (ligand) superfamily, member 13 (TNFSF13)
  • SLAN protein (SLAN)
  • TNF superfamily member 13 (april)
  • TNFSF12-TNFSF13 readthrough transcript (TNFSF12-TNFSF13)
  • tumor necrosis factor (ligand) superfamily, member 13 (tnfsf13)
  • a proliferation-inducing ligand (APRIL)
  • tumor necrosis factor (ligand) superfamily, member 13 (Tnfsf13)
  • 2310026N09Rik protein
  • ANP32B protein
  • April protein
  • CD256 protein
  • SLAN protein
  • TALL-2 protein
  • Tall2 protein
  • tnf13 protein
  • TNFSF12-TNFSF13 protein
  • TNFSF13 protein
  • TRDL-1 protein
  • Trdl1 protein
  • ZTNF2 protein

Protein level used designations for TNFSF13

tumor necrosis factor ligand superfamily member 13 , tumor necrosis factor ligand superfamily member 13 isoform alpha proprotein , SLAN protein , Acidic leucine-rich nuclear phosphoprotein 32 family member B , TNF superfamily member 13 , TNFSF12-TNFSF13 readthrough transcript , tumor necrosis factor superfamily member 13 , tumor necrosis factor (ligand) superfamily, member 13 , TNF- and APOL-related leukocyte expressed ligand 2 , a proliferation-inducing ligand , tumor necrosis factor-like protein ZTNF2 , tumor necrosis factor-related death ligand-1 , A proliferation-inducing ligand

GENE ID SPECIES
100551507 Macaca mulatta
494442 Ovis aries
100136706 Oncorhynchus mykiss
479484 Canis lupus familiaris
749008 Pan troglodytes
100196575 Salmo salar
100434469 Pongo abelii
100551504 Pan troglodytes
100551510 Callithrix jacchus
100551512 Monodelphis domestica
100127162 Sus scrofa
8741 Homo sapiens
69583 Mus musculus
287437 Rattus norvegicus
538567 Bos taurus
100860886 Capra hircus
100568281 Canis lupus familiaris
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