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The protein encoded by TNFSF8 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. Additionally we are shipping Tumor Necrosis Factor (Ligand) Superfamily, Member 8 Antibodies (108) and Tumor Necrosis Factor (Ligand) Superfamily, Member 8 Kits (40) and many more products for this protein.
Showing 10 out of 22 products:
Mouse (Murine) TNFSF8 Protein expressed in CHO Cells - ABIN2666787
Croft, Benedict, Ware: Clinical targeting of the TNF and TNFR superfamilies. in Nature reviews. Drug discovery 2013
Show all 6 references for ABIN2666787
Human TNFSF8 Protein expressed in Human Cells - ABIN2001944
Gruss, Boiani, Williams, Armitage, Smith, Goodwin: Pleiotropic effects of the CD30 ligand on CD30-expressing cells and lymphoma cell lines. in Blood 1994
Show all 5 references for ABIN2001944
Rat (Rattus) TNFSF8 Protein expressed in Human Cells - ABIN2009208
Croager, Abraham: Characterisation of the human CD30 ligand gene structure. in Biochimica et biophysica acta 1997
Show all 5 references for ABIN2009208
Cynomolgus TNFSF8 Protein expressed in Human Cells - ABIN2009819
Wendtner, Schmitt, Gruss, Druker, Emmerich, Goodwin, Hallek: CD30 ligand signal transduction involves activation of a tyrosine kinase and of mitogen-activated protein kinase in a Hodgkin's lymphoma cell line. in Cancer research 1995
Show all 5 references for ABIN2009819
Data indicate that CD30L/CD30 (show TNFRSF8 Proteins) axis plays a modulatory role in the pathogenesis of experimental autoimmune encephalomyelitis (EAE).
Altered expression of CD30L and IL-3 (show Il3 Proteins) may be potential biomarkers for hepatotoxicity induced by D. bulbifera.
role in the maintenance and activation of IL-17A (show IL17A Proteins)-producing gammadelta T cells
Interference of the CD30 (show TNFRSF8 Proteins)-CD30L pathway reduces atherosclerosis development.
It is shown here that CD30L knock out (KO) mice are highly susceptible to primary infection with Listeria monocytogenes as assessed by the survival rate.
role of CD30L/CD30 (show TNFRSF8 Proteins) interactions in allergic rhinitis; results suggest that CD30L plays an important role in allergic rhinitis
Modulation of CD30L/CD30 (show TNFRSF8 Proteins) signaling by soluble CD30 (show TNFRSF8 Proteins) could be a novel biological therapy for inflammatory diseases associated with Th17 responses.
Studies demonstrate that CD30L/CD30 (show TNFRSF8 Proteins) signaling executed by the T-T cell interaction plays a critical role in Th17 cell differentiation.
Characterization of the murine CD30 ligand (CD153) gene: gene structure and expression.
CD30L is required for generation of long-lived memory CD8 (show CD8A Proteins)+ T cells; CD30L signaling triggers homing receptors for T(central memory) cells.
circulant sCD30L is functionally active and that it may favor persistence of active inflammation by inducing apoptosis of CD30 (show TNFRSF8 Proteins)(+)T cells, known to down-modulate inflammation in rheumatoid synovitis.
TNFSF8 is an important leprosy T1R susceptibility gene.
The heritability of IgA levels is moderate and can partly be attributable to common variation in the CD30L locus.
soluble apoptosis markers as sFas-L, Caspase-9 (show CASP9 Proteins), Caspase-8 (show CASP8 Proteins) and sCD153 were significantly higher in stage III obesity patients compared obese patients without food allergy
a novel and unexpected role for CD30 (show TNFRSF8 Proteins)/CD30L that contributes to proinflammatory immune responses
The TNFSF8 polymorphisms rs927374 and rs2295800 were associated with neutrophil count. This finding suggests that post-MI inflammatory response is genetically modulated.
Positional candidate gene screening in the SPA2 locus allowed us to identify and replicate an association between a rare SNP located in TNFSF8 and spondylarthritis.
a possible role of novel TNFSF8 variants in susceptibility to lung cancer.
capability to up-regulate expression of CD30 (show TNFRSF8 Proteins), release of soluble CD30 (show TNFRSF8 Proteins) and production of IL-4 (show IL4 Proteins) in pre-activated T cells upon co-culture
only in a subset of both benign and malignant thyroid nodules the interleukin-6/interleukin-6 (show IL6 Proteins) receptor (show IL6ST Proteins) signal could be induced by the CD30 ligand/CD30 (show TNFRSF8 Proteins)
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene.
tumor necrosis factor (ligand) superfamily, member 8
, CD30 antigen ligand
, CD30 ligand
, tumor necrosis factor ligand superfamily member 8
, CD153 antigen