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TNFSF9 Proteins

(Tumor Necrosis Factor (Ligand) Superfamily, Member 9 (TNFSF9))
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.[provided by RefSeq, Oct 2008].
TNFSF9 Protein (Trimer) (Fc Tag) TNFSF9 Protein (Trimer) (Fc Tag) TNFSF9 Protein (Trimer) (Fc Tag) (ABIN7273929)

TNFSF9 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE

TNFSF9 Protein (Trimer) (His tag) TNFSF9 Protein (Trimer) (His tag) TNFSF9 Protein (Trimer) (His tag) (ABIN7273928)

TNFSF9 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

TNFSF9 Protein (AA 68-251) (Fc Tag) TNFSF9 Protein (AA 68-251) (Fc Tag) TNFSF9 Protein (AA 68-251) (Fc Tag) (ABIN7273927)

TNFSF9 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

TNFSF9 Proteins by Grade

Find TNFSF9 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

TNFSF9 Proteins by Origin

Find TNFSF9 Proteins for a variety of species such as anti-Human TNFSF9, anti-Mouse TNFSF9, anti-Cynomolgus TNFSF9. The species listed below are among those available. Click on a link to go to the corresponding products.

TNFSF9 Proteins by Source

Here you will find TNFSF9 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

TNFSF9 Proteins by Protein Type

Here you can find TNFSF9 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

TNFSF9 Proteins by Application

Find TNFSF9 Proteins validated for a specific application such as SDS, WB, ELISA, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

TNFSF9 Proteins by Biological Activity

Find TNFSF9 Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular TNFSF9 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7273929
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7273928
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7273927
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7273930
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN6961118
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293T Cells
Validations
  • (2)
Cat. No. ABIN4369886
Quantity 2 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (2)
Cat. No. ABIN7319954
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320663
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125533
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1323254
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3074145
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3134007
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3097645
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3134006
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN6952261
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our TNFSF9 Proteins

Won, Cha, Byun, Kim, Shin, Ahn, Kim, Rice, Walz, Kwon, Cho: "The structure of the trimer of human 4-1BB ligand is unique among members of the tumor necrosis factor superfamily." in: The Journal of biological chemistry, Vol. 285, Issue 12, pp. 9202-10, (2010) (PubMed).

Rabu, Quéméner, Jacques, Echasserieau, Vusio, Lang: "Production of recombinant human trimeric CD137L (4-1BBL). Cross-linking is essential to its T cell co-stimulation activity." in: The Journal of biological chemistry, Vol. 280, Issue 50, pp. 41472-81, (2005) (PubMed).

Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).

Xu, Zhang, Han, Zhang: "[Binding between alpha 1A-adrenergic receptor and segment of bone morphogenetic protein-1 in human embryonic cell 293]." in: Sheng li xue bao : [Acta physiologica Sinica], Vol. 55, Issue 6, pp. 692-8, (2003) (PubMed).

Alderson, Smith, Tough, Davis-Smith, Armitage, Falk, Roux, Baker, Sutherland, Din: "Molecular and biological characterization of human 4-1BB and its ligand." in: European journal of immunology, Vol. 24, Issue 9, pp. 2219-27, (1994) (PubMed).

Aliases for TNFSF9 Proteins

TNF superfamily member 9 (Tnfsf9) Proteins
TNF superfamily member 9 (LOC476729) Proteins
TNF superfamily member 9 (TNFSF9) Proteins
tumor necrosis factor (ligand) superfamily, member 9 (Tnfsf9) Proteins
4-1BB-L Proteins
4-1BBL Proteins
AI848817 Proteins
Cd137l Proteins
CD137L Proteins
Ly63l Proteins
TNFSF9 Proteins
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