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anti-Tumor Necrosis Factor (Ligand) Superfamily Member 14 (TNFSF14) Antibodies

The protein encoded by TNFSF14 is a member of the tumor necrosis factor (TNF) ligand family.

list all antibodies Gene Name GeneID UniProt
Anti-Human TNFSF14 TNFSF14 8740 O43557
Anti-Rat TNFSF14 TNFSF14 301133  
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More Antibodies against Tumor Necrosis Factor (Ligand) Superfamily Member 14 Interaction Partners

Human Tumor Necrosis Factor (Ligand) Superfamily Member 14 (TNFSF14) interaction partners

  1. LIGHT, via LTbetaR signaling, may contribute to exacerbation of airway neutrophilic inflammation through cytokine and chemokine (show CCL1 Antibodies) production by bronchial epithelial cells.

  2. LIGHT controls TSLP (show TSLP Antibodies) to drive pulmonary fibrosis.

  3. The tumor necrosis factor (show TNF Antibodies) superfamily molecule LIGHT promotes keratinocyte activity and skin fibrosis.

  4. proliferation and migration would be enhanced in Tca8113 cells with over-expressed TNFSF14

  5. LIGHT, a TNF (show TNF Antibodies) superfamily member, is involved in T-cell homeostasis and erosive bone disease associated with rheumatoid arthritis.

  6. Crystal structures of LIGHT and the LIGHT:DcR3 complex reveal the structural basis for the DcR3 (show TNFRSF6B Antibodies)-mediated neutralization of LIGHT.

  7. regulation by NK cell licensing helps to safeguard against TNFSF14 production in response to healthy tissues.

  8. TNFSF14 has an effect on the activation of basophils and eosinophils interacting with bronchial epithelial cells

  9. Triggering of LIGHT induced production of pro-inflammatory mediators such as interleukin-8 (show IL8 Antibodies) and matrix metalloproteinase-9 (show MMP9 Antibodies) while suppressing the phagocytic activity.

  10. findings show that LIGHT is not inhibited by the soluble RANKL (show TNFSF11 Antibodies) receptor OPG (show TNFRSF11B Antibodies) and that LIGHT is a potent osteoclastogenesis factor that activates the Akt (show AKT1 Antibodies), NFkappaB (show NFKB1 Antibodies) and JNK (show MAPK8 Antibodies) pathways

Tumor Necrosis Factor (Ligand) Superfamily Member 14 (TNFSF14) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.

Gene names and symbols associated with TNFSF14

  • tumor necrosis factor (ligand) superfamily, member 14 (TNFSF14) antibody
  • tumor necrosis factor (ligand) superfamily, member 14 (Tnfsf14) antibody
  • tumor necrosis factor ligand superfamily, member 14 (LOC100347876) antibody
  • CD258 antibody
  • HVEML antibody
  • LIGHT antibody
  • LTg antibody
  • TNFSF14 antibody
  • TR2 antibody

Protein level used designations for TNFSF14

delta transmembrane LIGHT , herpes virus entry mediator ligand , herpesvirus entry mediator A , herpesvirus entry mediator ligand , herpesvirus entry mediator-ligand , ligand for herpesvirus entry mediator , tumor necrosis factor ligand superfamily member 14 , tumor necrosis factor receptor-like 2 , tumor necrosis factor superfamily member LIGHT , tumor necrosis factor ligand superfamily, member 14 , tumor necrosis factor (ligand) superfamily, member 14

GENE ID SPECIES
8740 Homo sapiens
301133 Rattus norvegicus
468687 Pan troglodytes
505521 Bos taurus
611306 Canis lupus familiaris
701451 Macaca mulatta
100347876 Oryctolagus cuniculus
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