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anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (Osteoprotegerin) (TNFRSF11B) Antibodies

Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Additionally we are shipping Tumor Necrosis Factor Receptor Superfamily, Member 11b (Osteoprotegerin) Proteins (13) and Tumor Necrosis Factor Receptor Superfamily, Member 11b (Osteoprotegerin) Kits (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TNFRSF11B 690  
TNFRSF11B 25341 O08727
TNFRSF11B 18383 O08712
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Top anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (Osteoprotegerin) Antibodies at antibodies-online.com

Showing 10 out of 49 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-TNFRSF11B Antibody Titration: 1.25ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Mouse Un-conjugated ICC, FACS, ELISA, WB Figure 1: Flow cytometric analysis of HL-60 cells using TNFRSF11B mouse mAb (green) and negative control (purple) . Figure 2: Immunofluorescence analysis of HL-60 cells using TNFRSF11B mouse mAb (green) . Blue: DRAQ5 fluorescent DNA dye. 100 μL Log in to see 3 to 4 Days
$393.80
Details
Human Mouse Un-conjugated IHC, ELISA, WB Figure 1: Immunohistochemical analysis of paraffin-embedded mammary cancer tissues (left) and lung cancer tissues (right) using TNFRSF11B mouse mAb with DAB staining. Figure 2: Western blot analysis using TNFRSF11B mAb against HEK293 (1) and TNFRSF11B (AA: 22-401) -hIgGFc transfected HEK293 (2) cell lysate. 100 μL Log in to see 3 to 4 Days
$393.80
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Confocal immunofluorescent analysis of TNFRSF11B Antibody (Center) (ABIN657660) with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$200.00
Details
Gibbon Mouse Un-conjugated IHC, WB 0.05 mg Log in to see 2 to 3 Days
$481.25
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Mouse Un-conjugated IHC, ELISA, WB 0.1 mL Log in to see 6 to 11 Days
$478.57
Details
Mouse Rabbit Un-conjugated IHC, WB Immunohistochemistry of paraffin-embedded human stomach cancer using TNFRSF11B antibody at dilution of 1:200 (x400 lens) Western blot analysis of extracts of various cell lines, using TNFRSF11B antibody. 100 μL Log in to see 9 Days
$302.50
Details

TNFRSF11B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine) ,
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Top referenced anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (Osteoprotegerin) Antibodies

  1. Human Monoclonal TNFRSF11B Primary Antibody for ICC, FACS - ABIN969439 : Golledge, Biros, Clancy, Cooper, Palmer, Norman: A single-nucleotide polymorphism in the gene encoding osteoprotegerin is associated with diastolic blood pressure in older men. in American journal of hypertension 2009 (PubMed)
    Show all 2 references for ABIN969439

  2. Human Monoclonal TNFRSF11B Primary Antibody for IHC, ELISA - ABIN969440 : Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ... in American journal of human genetics 2009 (PubMed)
    Show all 2 references for ABIN969440

  3. Dog (Canine) Polyclonal TNFRSF11B Primary Antibody for WB - ABIN2792104 : Cross, Yang, Brown, Balasubramanian, Evans, Woodward, Neville-Webbe, Lippitt, Reed, Coleman, Holen: Osteoprotegerin (OPG)--a potential new role in the regulation of endothelial cell phenotype and tumour angiogenesis? in International journal of cancer. Journal international du cancer 2006 (PubMed)

More Antibodies against Tumor Necrosis Factor Receptor Superfamily, Member 11b (Osteoprotegerin) Interaction Partners

Pig (Porcine) Tumor Necrosis Factor Receptor Superfamily, Member 11b (Osteoprotegerin) (TNFRSF11B) interaction partners

  1. Regional variation of periosteal activity at the mandibular ramus is regulated by differential expression of osteoprotegerin.

Rabbit Tumor Necrosis Factor Receptor Superfamily, Member 11b (Osteoprotegerin) (TNFRSF11B) interaction partners

  1. Low-frequency vibration may promote the osteogenic differentiation capability of BMSC probably through regulating the OPG/RANKL (show TNFSF11 Antibodies) mRNA expression.

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 11b (Osteoprotegerin) (TNFRSF11B) interaction partners

  1. OPG (show TNFSF11 Antibodies) expression in chondrocyte increases bone mass in the proximal metaphysis of tibiae through negative regulation of osteoclast formation.

  2. the generation of Rag2GFP+ regulatory T cells is unaltered in Tnfrsf11b(-/-) mice

  3. identify osteoprotegerin as a HIF target gene capable of directing osteoblast-mediated osteoclastogenesis to regulate bone homeostasis

  4. Osteoprotegerin is increased in metabolic syndrome and promotes adipose tissue proinflammatory changes.

  5. Osteoprotegerin inhibits vascular calcification by regulating the procalcific effects of RANKL (show TNFSF11 Antibodies) and Il6 (show IL6 Antibodies) on vascular smooth muscle cells.

  6. These results indicate that OPG (show TNFSF11 Antibodies) derived either from the bone marrow or from the vessel wall is sufficient to slow down lesion progression and vascular calcification independent of bone turnover.

  7. High concentrations of alendronate decrease the expressions of OPG (show TNFSF11 Antibodies) and RANKL (show TNFSF11 Antibodies) in cultured osteoblasts.

  8. In a xenograft model, increased osteoprotegerin expression correlated with a delay to pathologic fracture suggesting a potential role for mTOR (show FRAP1 Antibodies) inhibitors in the treatment of neuroblastoma (show ARHGEF16 Antibodies) bone metastases.

  9. Data indicate in TLR4 (show TLR4 Antibodies)(-/-) mice, higher expression levels of IL-1beta (show IL1B Antibodies) and lower expression levels of VEGF (show VEGFA Antibodies), RANK, RANKL (show TNFSF11 Antibodies) and OPG (show TNFSF11 Antibodies) were detected at late time points (> postoperative 4 days).

  10. Coptisine inhibits RANKL (show TNFSF11 Antibodies)-induced NF-kappaB (show NFKB1 Antibodies) phosphorylation in osteoclast precursors and suppresses function through the regulation of RANKL (show TNFSF11 Antibodies) and OPG (show TNFSF11 Antibodies) gene expression in osteoblastic cells.

Tumor Necrosis Factor Receptor Superfamily, Member 11b (Osteoprotegerin) (TNFRSF11B) Antigen Profile

Protein Summary

Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis (By similarity).

Gene names and symbols associated with TNFRSF11B

  • basic transcription factor 3 pseudogene 11 (BTF3P11) antibody
  • tumor necrosis factor receptor superfamily, member 11b (TNFRSF11B) antibody
  • tumor necrosis factor receptor superfamily, member 11b (Tnfrsf11b) antibody
  • tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) (Tnfrsf11b) antibody
  • BTF3L1 antibody
  • HUMBTFB antibody
  • OCIF antibody
  • Opg antibody
  • TNFRSF11B antibody
  • TR1 antibody

Protein level used designations for TNFRSF11B

tumor necrosis factor receptor superfamily, member 11b , tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) , osteoprotegerin , Osteoprotegerin , tumor necrosis factor receptor superfamily member 11B , osteoclastogenesis inhibitory factor

GENE ID SPECIES
690 Homo sapiens
482025 Canis lupus familiaris
100049688 Sus scrofa
100348133 Oryctolagus cuniculus
25341 Rattus norvegicus
18383 Mus musculus
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