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anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Antibodies

The protein encoded by TNFRSF11B is a member of the TNF-receptor superfamily. Additionally we are shipping Tumor Necrosis Factor Receptor Superfamily, Member 11b Kits (60) and Tumor Necrosis Factor Receptor Superfamily, Member 11b Proteins (29) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TNFRSF11B 4982 O00300
TNFRSF11B 25341 O08727
TNFRSF11B 18383 O08712
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Top anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b Antibodies at antibodies-online.com

Showing 10 out of 119 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated ICC, FACS, IHC (fro), IF, IHC (p), IP, IHC, WB Western blot analysis for OPG with IMG-103A antibody against Daudi cell lysate. Daudi cell lysate blot was incubated with ABIN252469 at a dilution of 1 µg/ml and the immunoreactivity was detected by enhanced chemiluminescence. Flow Cytometry: Osteoprotegerin/TNFRSF11B Antibody (98A1071) [ABIN2524695] - Intracellular staining of 10^6 HeLa cells using 0.2 ug of OPG antibody, 0.5 ul of PE secondary. 0.1 mg Log in to see 5 to 7 Days
$408.19
Details
Cow Rabbit Un-conjugated IHC, ELISA, WB Osteoprotegerin staining of rat articular cartilage disk. Paraffin-embedded rat articular cartilage disk tissue is stained with Osteoprotegerin Antibody used at 1:200 dilution. 0.1 mg Log in to see 2 to 6 Days
$327.00
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated EIA, WB   0.1 mg Log in to see 6 to 8 Days
$478.50
Details
Human Mouse Un-conjugated EIA, WB   0.1 mg Log in to see 6 to 8 Days
$478.50
Details
Human Mouse Un-conjugated WB   0.1 mg Log in to see 5 to 6 Days
$346.50
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated EIA, FACS, IF, WB 0.1 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IHC (p), WB Human Liver (formalin-fixed, paraffin-embedded) stained with TNFRSF11B antibody ABIN296455 at 5 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. Human Heart (formalin-fixed, paraffin-embedded) stained with TNFRSF11B antibody ABIN296455 at 5 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of Osteoprotegerin staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of Osteoprotegerin staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 9 Days
$487.50
Details

TNFRSF11B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus)
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Mouse (Murine)


Top referenced anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b Antibodies

  1. Human Monoclonal TNFRSF11B Primary Antibody for ICC, FACS - ABIN252469 : Kobayashi, Hashimoto, Miyamoto, Kanaoka, Miyazaki-Kawashita, Nakashima, Shibata, Kobayashi, Kato, Sakai: Force-induced osteoclast apoptosis in vivo is accompanied by elevation in transforming growth factor beta and osteoprotegerin expression. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001 (PubMed)
    Show all 25 references for ABIN252469

  2. Human Monoclonal TNFRSF11B Primary Antibody for WB - ABIN108499 : Simonet, Lacey, Dunstan, Kelley, Chang, Lüthy, Nguyen, Wooden, Bennett, Boone, Shimamoto, DeRose, Elliott, Colombero, Tan, Trail, Sullivan, Davy, Bucay, Renshaw-Gegg, Hughes, Hill, Pattison, Campbell et al.: Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. ... in Cell 1997 (PubMed)
    Show all 5 references for ABIN108499

  3. Human Monoclonal TNFRSF11B Primary Antibody for EIA, WB - ABIN114693 : Bolten, Weissbach, Kaden: [Cryopreserved human sperm deposits: usability after decades of storage] in Der Urologe. Ausg. A 2005 (PubMed)
    Show all 3 references for ABIN114693

  4. Human Monoclonal TNFRSF11B Primary Antibody for EIA, WB - ABIN114706 : Yasuda, Shima, Nakagawa, Mochizuki, Yano, Fujise, Sato, Goto, Yamaguchi, Kuriyama, Kanno, Murakami, Tsuda, Morinaga, Higashio: Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG): a mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitro. in Endocrinology 1998 (PubMed)
    Show all 3 references for ABIN114706

  5. Human Monoclonal TNFRSF11B Primary Antibody for EIA, FACS - ABIN1108534 : Golledge, Biros, Clancy, Cooper, Palmer, Norman: A single-nucleotide polymorphism in the gene encoding osteoprotegerin is associated with diastolic blood pressure in older men. in American journal of hypertension 2009 (PubMed)
    Show all 2 references for ABIN1108534

  6. Human Monoclonal TNFRSF11B Primary Antibody for EIA, IHC (p) - ABIN1108535 : Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ... in American journal of human genetics 2009 (PubMed)
    Show all 2 references for ABIN1108535

  7. Cow (Bovine) Polyclonal TNFRSF11B Primary Antibody for IHC, ELISA - ABIN1582232 : Fradet, Sorel, Bouazza, Goehrig, Dépalle, Bellahcène, Castronovo, Follet, Descotes, Aubin, Clézardin, Bonnelye: Dual function of ERRα in breast cancer and bone metastasis formation: implication of VEGF and osteoprotegerin. in Cancer research 2011 (PubMed)
    Show all 2 references for ABIN1582232

More Antibodies against Tumor Necrosis Factor Receptor Superfamily, Member 11b Interaction Partners

Human Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. Osteoprotegerin reduction seems to play a pivotal role in the progression of arthropathy in hemophilia A.

  2. Recurrent amplification of MYC (show MYC Antibodies) and TNFRSF11B in 8q24 is associated with poor survival in patients with gastric cancer.

  3. this study shows that OPG constitutes a novel biomarker with prognostic significance in patients with severe malaria

  4. Overexpression of OPG in OCCM (show LAMC3 Antibodies)-30 cells promotes cementoblastic activity

  5. This study demonstrates that clodronate decreases the compression-induced RANKL/OPG (show TNFSF11 Antibodies) ratio expressed by human osteoblasts.

  6. OPG and RANKL (show TNFSF11 Antibodies) may play an integral role in breast cancer cells homing to the bone environment

  7. This study implicates that osteoprotegerin gene variants may be associated with early-onset severe pre-eclampsia.

  8. In lung cancer, serum OPG levels in the BM and BM- groups were significantly increased compared with healthy controls.

  9. Alendronate stimulated OPG mRNA and protein expression, but not RANKL (show TNFSF11 Antibodies) expression, in fibroblasts from patients with aseptic loosening following total hip arthroplasty.

  10. Single nucleotide polymorphisms (SNPs) rs1035798 in RAGE (show AGER Antibodies) gene, rs2073617 and rs2073618 in TNFRSF11B, and rs3732410 in Golgb1 (show GOLGB1 Antibodies) will be investigated on whether there is an association with hemorrhagic stroke (HS) in Chinese population.

Rabbit Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. The OPG (show TNFSF11 Antibodies) expression levels decreased while those of RANKL (show TNFSF11 Antibodies) and RUNX2 (show RUNX2 Antibodies) increased during orthodontic tooth movement, which suggested that they play a role in the osteogenesis process and the reconstruction of periodontal tissue.

  2. Low-frequency vibration may promote the osteogenic differentiation capability of BMSC probably through regulating the OPG/RANKL (show TNFSF11 Antibodies) mRNA expression.

Pig (Porcine) Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. Regional variation of periosteal activity at the mandibular ramus is regulated by differential expression of osteoprotegerin.

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. Data show that p38alpha (show MAPK14 Antibodies) mitogen-activated protein kinase (show MAPK1 Antibodies) (MAPK (show MAPK1 Antibodies)) in paired related homeobox 1 (show PRRX1 Antibodies) protein (Prx1 (show PRDX1 Antibodies)+) bone marrow-derived mesenchymal stromal cells acts to preserve the bone by sustaining osteoprotegerin (OPG) production.

  2. OPG (show TNFSF11 Antibodies) expression in chondrocyte increases bone mass in the proximal metaphysis of tibiae through negative regulation of osteoclast formation.

  3. the generation of Rag2GFP+ regulatory T cells is unaltered in Tnfrsf11b(-/-) mice

  4. identify osteoprotegerin as a HIF target gene capable of directing osteoblast-mediated osteoclastogenesis to regulate bone homeostasis

  5. Osteoprotegerin is increased in metabolic syndrome and promotes adipose tissue proinflammatory changes.

  6. Osteoprotegerin inhibits vascular calcification by regulating the procalcific effects of RANKL (show TNFSF11 Antibodies) and Il6 (show IL6 Antibodies) on vascular smooth muscle cells.

  7. These results indicate that OPG (show TNFSF11 Antibodies) derived either from the bone marrow or from the vessel wall is sufficient to slow down lesion progression and vascular calcification independent of bone turnover.

  8. High concentrations of alendronate decrease the expressions of OPG (show TNFSF11 Antibodies) and RANKL (show TNFSF11 Antibodies) in cultured osteoblasts.

  9. In a xenograft model, increased osteoprotegerin expression correlated with a delay to pathologic fracture suggesting a potential role for mTOR (show FRAP1 Antibodies) inhibitors in the treatment of neuroblastoma (show ARHGEF16 Antibodies) bone metastases.

  10. Data indicate in TLR4 (show TLR4 Antibodies)(-/-) mice, higher expression levels of IL-1beta (show IL1B Antibodies) and lower expression levels of VEGF (show VEGFA Antibodies), RANK, RANKL (show TNFSF11 Antibodies) and OPG (show TNFSF11 Antibodies) were detected at late time points (> postoperative 4 days).

Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

Gene names and symbols associated with TNFRSF11B

  • tumor necrosis factor receptor superfamily, member 11b (TNFRSF11B) antibody
  • tumor necrosis factor receptor superfamily, member 11b (tnfrsf11b) antibody
  • osteoprotegerin (LOC100037695) antibody
  • tumor necrosis factor receptor superfamily, member 11b (Tnfrsf11b) antibody
  • tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) (Tnfrsf11b) antibody
  • OCIF antibody
  • Opg antibody
  • TR1 antibody

Protein level used designations for TNFRSF11B

osteoprotegerin , tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) , Osteoprotegerin , tumor necrosis factor receptor superfamily, member 11b , tumor necrosis factor receptor superfamily member 11B-like , osteoclastogenesis inhibitory factor , tumor necrosis factor receptor superfamily member 11B

GENE ID SPECIES
464351 Pan troglodytes
444716 Xenopus laevis
482025 Canis lupus familiaris
701850 Macaca mulatta
100399751 Callithrix jacchus
100433420 Pongo abelii
100465761 Ailuropoda melanoleuca
100599407 Nomascus leucogenys
100037695 Ovis aries
4982 Homo sapiens
100348133 Oryctolagus cuniculus
25341 Rattus norvegicus
100860896 Capra hircus
100049688 Sus scrofa
523822 Bos taurus
100065885 Equus caballus
18383 Mus musculus
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