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Tumor Necrosis Factor Receptor Superfamily, Member 11b Proteins (TNFRSF11B)

The protein encoded by TNFRSF11B is a member of the TNF-receptor superfamily. Additionally we are shipping Tumor Necrosis Factor Receptor Superfamily, Member 11b Antibodies (119) and Tumor Necrosis Factor Receptor Superfamily, Member 11b Kits (60) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TNFRSF11B 4982 O00300
TNFRSF11B 25341 O08727
Mouse TNFRSF11B TNFRSF11B 18383 O08712
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Top Tumor Necrosis Factor Receptor Superfamily, Member 11b Proteins at antibodies-online.com

Showing 10 out of 29 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag 100 μg Log in to see 2 to 3 Days
$198.00
Details
HOST_Hi-5 Human His tag 30 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Mammalian Cells Human His tag   50 μg Log in to see 5 Days
$170.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$225.75
Details
HOST_HEK-293 Human His tag   20 μg Log in to see 2 to 3 Days
$183.75
Details
HOST_HEK-293 Human His tag   0.1 mg Log in to see 2 to 3 Days
$378.13
Details
HOST_HEK-293 Human Fc Tag   0.1 mg Log in to see 2 to 3 Days
$378.13
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 7 to 9 Days
$413.21
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,045.17
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,048.83
Details

TNFRSF11B Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
,
Rat (Rattus)

Top referenced Tumor Necrosis Factor Receptor Superfamily, Member 11b Proteins

  1. Human TNFRSF11B Protein expressed in HEK-293 Cells - ABIN2181847 : Tsuda, Goto, Mochizuki, Yano, Kobayashi, Morinaga, Higashio: Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesis. in Biochemical and biophysical research communications 1997 (PubMed)
    Show all 4 references for ABIN2181847

  2. Human TNFRSF11B Protein expressed in Hi-5 - ABIN666742 : Yasuda, Shima, Nakagawa, Yamaguchi, Kinosaki, Mochizuki, Tomoyasu, Yano, Goto, Murakami, Tsuda, Morinaga, Higashio, Udagawa, Takahashi, Suda: Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. in Proceedings of the National Academy of Sciences of the United States of America 1998 (PubMed)
    Show all 3 references for ABIN666742

More Proteins for Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Interaction Partners

Human Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. Osteoprotegerin reduction seems to play a pivotal role in the progression of arthropathy in hemophilia A.

  2. Recurrent amplification of MYC (show MYC Proteins) and TNFRSF11B in 8q24 is associated with poor survival in patients with gastric cancer.

  3. this study shows that OPG constitutes a novel biomarker with prognostic significance in patients with severe malaria

  4. Overexpression of OPG in OCCM (show LAMC3 Proteins)-30 cells promotes cementoblastic activity

  5. This study demonstrates that clodronate decreases the compression-induced RANKL/OPG (show TNFSF11 Proteins) ratio expressed by human osteoblasts.

  6. OPG and RANKL (show TNFSF11 Proteins) may play an integral role in breast cancer cells homing to the bone environment

  7. This study implicates that osteoprotegerin gene variants may be associated with early-onset severe pre-eclampsia.

  8. In lung cancer, serum OPG levels in the BM and BM- groups were significantly increased compared with healthy controls.

  9. Alendronate stimulated OPG mRNA and protein expression, but not RANKL (show TNFSF11 Proteins) expression, in fibroblasts from patients with aseptic loosening following total hip arthroplasty.

  10. Single nucleotide polymorphisms (SNPs) rs1035798 in RAGE gene, rs2073617 and rs2073618 in TNFRSF11B, and rs3732410 in Golgb1 will be investigated on whether there is an association with hemorrhagic stroke (HS) in Chinese population.

Rabbit Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. The OPG (show TNFSF11 Proteins) expression levels decreased while those of RANKL (show TNFSF11 Proteins) and RUNX2 (show RUNX2 Proteins) increased during orthodontic tooth movement, which suggested that they play a role in the osteogenesis process and the reconstruction of periodontal tissue.

  2. Low-frequency vibration may promote the osteogenic differentiation capability of BMSC probably through regulating the OPG/RANKL (show TNFSF11 Proteins) mRNA expression.

Pig (Porcine) Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. Regional variation of periosteal activity at the mandibular ramus is regulated by differential expression of osteoprotegerin.

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. Data show that p38alpha (show MAPK14 Proteins) mitogen-activated protein kinase (show MAPK1 Proteins) (MAPK (show MAPK1 Proteins)) in paired related homeobox 1 (show PRRX1 Proteins) protein (Prx1 (show PRDX1 Proteins)+) bone marrow-derived mesenchymal stromal cells acts to preserve the bone by sustaining osteoprotegerin (OPG) production.

  2. OPG (show TNFSF11 Proteins) expression in chondrocyte increases bone mass in the proximal metaphysis of tibiae through negative regulation of osteoclast formation.

  3. the generation of Rag2GFP+ regulatory T cells is unaltered in Tnfrsf11b(-/-) mice

  4. identify osteoprotegerin as a HIF target gene capable of directing osteoblast-mediated osteoclastogenesis to regulate bone homeostasis

  5. Osteoprotegerin is increased in metabolic syndrome and promotes adipose tissue proinflammatory changes.

  6. Osteoprotegerin inhibits vascular calcification by regulating the procalcific effects of RANKL (show TNFSF11 Proteins) and Il6 (show IL6 Proteins) on vascular smooth muscle cells.

  7. These results indicate that OPG (show TNFSF11 Proteins) derived either from the bone marrow or from the vessel wall is sufficient to slow down lesion progression and vascular calcification independent of bone turnover.

  8. High concentrations of alendronate decrease the expressions of OPG (show TNFSF11 Proteins) and RANKL (show TNFSF11 Proteins) in cultured osteoblasts.

  9. In a xenograft model, increased osteoprotegerin expression correlated with a delay to pathologic fracture suggesting a potential role for mTOR (show FRAP1 Proteins) inhibitors in the treatment of neuroblastoma (show ARHGEF16 Proteins) bone metastases.

  10. Data indicate in TLR4 (show TLR4 Proteins)(-/-) mice, higher expression levels of IL-1beta (show IL1B Proteins) and lower expression levels of VEGF (show VEGFA Proteins), RANK, RANKL (show TNFSF11 Proteins) and OPG (show TNFSF11 Proteins) were detected at late time points (> postoperative 4 days).

Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

Gene names and symbols associated with TNFRSF11B

  • tumor necrosis factor receptor superfamily, member 11b (TNFRSF11B)
  • tumor necrosis factor receptor superfamily, member 11b (tnfrsf11b)
  • osteoprotegerin (LOC100037695)
  • tumor necrosis factor receptor superfamily, member 11b (Tnfrsf11b)
  • tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) (Tnfrsf11b)
  • OCIF protein
  • Opg protein
  • TR1 protein

Protein level used designations for TNFRSF11B

osteoprotegerin , tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) , Osteoprotegerin , tumor necrosis factor receptor superfamily, member 11b , tumor necrosis factor receptor superfamily member 11B-like , osteoclastogenesis inhibitory factor , tumor necrosis factor receptor superfamily member 11B

GENE ID SPECIES
464351 Pan troglodytes
444716 Xenopus laevis
482025 Canis lupus familiaris
701850 Macaca mulatta
100399751 Callithrix jacchus
100433420 Pongo abelii
100465761 Ailuropoda melanoleuca
100599407 Nomascus leucogenys
100037695 Ovis aries
4982 Homo sapiens
100348133 Oryctolagus cuniculus
25341 Rattus norvegicus
100860896 Capra hircus
100049688 Sus scrofa
523822 Bos taurus
100065885 Equus caballus
18383 Mus musculus
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