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Tumor Necrosis Factor Receptor Superfamily, Member 11b Proteins (TNFRSF11B)

The protein encoded by TNFRSF11B is a member of the TNF-receptor superfamily. Additionally we are shipping Tumor Necrosis Factor Receptor Superfamily, Member 11b Antibodies (119) and Tumor Necrosis Factor Receptor Superfamily, Member 11b Kits (64) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TNFRSF11B 4982 O00300
TNFRSF11B 25341 O08727
Mouse TNFRSF11B TNFRSF11B 18383 O08712
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Top Tumor Necrosis Factor Receptor Superfamily, Member 11b Proteins at antibodies-online.com

Showing 10 out of 28 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human Fc Tag Human Osteoprotegerin, Fc Tag on SDS-PAGE under reducing (R) and no-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 92%. 100 μg Log in to see 2 to 3 Days
$198.00
Details
HOST_Hi-5 Human His tag 30 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Mammalian Cells Human His tag   50 μg Log in to see 5 Days
$170.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$225.75
Details
HOST_HEK-293 Human His tag   0.1 mg Log in to see 2 to 3 Days
$378.13
Details
HOST_HEK-293 Human Fc Tag   0.1 mg Log in to see 2 to 3 Days
$378.13
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 7 to 9 Days
$413.21
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,045.17
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,048.83
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   0.01 mg Log in to see 2 to 3 Days
$178.75
Details

TNFRSF11B Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
,
Rat (Rattus)

Top referenced Tumor Necrosis Factor Receptor Superfamily, Member 11b Proteins

  1. Human TNFRSF11B Protein expressed in HEK-293 Cells - ABIN2181849 : Tsuda, Goto, Mochizuki, Yano, Kobayashi, Morinaga, Higashio: Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesis. in Biochemical and biophysical research communications 1997 (PubMed)
    Show all 4 references for ABIN2181849

  2. Human TNFRSF11B Protein expressed in Hi-5 - ABIN666742 : Yasuda, Shima, Nakagawa, Yamaguchi, Kinosaki, Mochizuki, Tomoyasu, Yano, Goto, Murakami, Tsuda, Morinaga, Higashio, Udagawa, Takahashi, Suda: Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. in Proceedings of the National Academy of Sciences of the United States of America 1998 (PubMed)
    Show all 3 references for ABIN666742

More Proteins for Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Interaction Partners

Human Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. the OPG/RANKL (show TNFSF11 Proteins)/RANK system might be directly influenced by genetic variants of NOTCH1 (show NOTCH1 Proteins) in aortic valve calcification.

  2. results suggest that serum OPG and RANKL (show TNFSF11 Proteins) levels are inversely associated with bone loss in men with advanced stage COPD (show ARCN1 Proteins).

  3. These data show that the osteoprotegerin and receptor-activator of nuclear factor-kappaB ligand system is associated with bone markers and bone mineral density at the lumbar spine after obesity surgery.

  4. Serum OPG level is associated with disease progression and death and enhance risk prediction in non-dialysis chronic kidney disease stages 3-5.

  5. OPG/TRAIL ratio can be proposed as a predictor of cardiovascular dysfunction and mortality.

  6. In ankylosing spondylitis patients, the serum OPG levels were not significantly correlated with pulse wave velocity and carotid intima-media thickness, but were significantly correlated with erthrocyte sedimentation rate, Bath Ankylosing Spondylitis Functional Index, and Ankylosing Spondylitis Disease Activity Score.

  7. The expression of Lrp6 (show LRP6 Proteins) was unaltered in the osteometastatic lesions. This negative regulation was associated with a lowered expression of osteoprotegerin in the osteometastatic lesions, an observation that was previously reported to promote osteoclastogenesis.

  8. OPG and RANKL (show TNFSF11 Proteins) polymorphisms were associated with the occurrence of alcohol-induced ONFH.

  9. Results demonstrated that the type of inflammatory infiltrate present in periradicular cysts appears to influence the expression of RANK, RANKL (show TNFSF11 Proteins), and osteoprotegerin

  10. The aim of this meta-analysis was to determine whether genetic polymorphisms in the osteoprotegerin (OPG) gene contribute to increased risk of cardiovascular disease (CVD). The results indicated that OPG gene polymorphism might be closely associated with susceptibility to CVD, especially for rs2073617 T>C and rs2073618 G>C polymorphisms.

Rabbit Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. The OPG (show TNFSF11 Proteins) expression levels decreased while those of RANKL (show TNFSF11 Proteins) and RUNX2 (show RUNX2 Proteins) increased during orthodontic tooth movement, which suggested that they play a role in the osteogenesis process and the reconstruction of periodontal tissue.

  2. Low-frequency vibration may promote the osteogenic differentiation capability of BMSC probably through regulating the OPG/RANKL (show TNFSF11 Proteins) mRNA expression.

Pig (Porcine) Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. Regional variation of periosteal activity at the mandibular ramus is regulated by differential expression of osteoprotegerin.

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. OPG (show TNFSF11 Proteins) plays an important role in regulating bone marrow mesenchymal stem cells differentiation and bone marrow adipogenesis.

  2. These data suggested that OPG (show TNFSF11 Proteins) played an important role in maintaining the homeostasis of articular cartilage of femoral head.

  3. Data show that p38alpha (show MAPK14 Proteins) mitogen-activated protein kinase (show MAPK1 Proteins) (MAPK (show MAPK1 Proteins)) in paired related homeobox 1 (show PRRX1 Proteins) protein (Prx1 (show PRDX1 Proteins)+) bone marrow-derived mesenchymal stromal cells acts to preserve the bone by sustaining osteoprotegerin (OPG) production.

  4. OPG (show TNFSF11 Proteins) expression in chondrocyte increases bone mass in the proximal metaphysis of tibiae through negative regulation of osteoclast formation.

  5. the generation of Rag2GFP+ regulatory T cells is unaltered in Tnfrsf11b(-/-) mice

  6. identify osteoprotegerin as a HIF target gene capable of directing osteoblast-mediated osteoclastogenesis to regulate bone homeostasis

  7. Osteoprotegerin is increased in metabolic syndrome and promotes adipose tissue proinflammatory changes.

  8. Osteoprotegerin inhibits vascular calcification by regulating the procalcific effects of RANKL (show TNFSF11 Proteins) and Il6 (show IL6 Proteins) on vascular smooth muscle cells.

  9. These results indicate that OPG (show TNFSF11 Proteins) derived either from the bone marrow or from the vessel wall is sufficient to slow down lesion progression and vascular calcification independent of bone turnover.

  10. High concentrations of alendronate decrease the expressions of OPG (show TNFSF11 Proteins) and RANKL (show TNFSF11 Proteins) in cultured osteoblasts.

Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

Gene names and symbols associated with TNFRSF11B

  • tumor necrosis factor receptor superfamily, member 11b (TNFRSF11B)
  • tumor necrosis factor receptor superfamily, member 11b (tnfrsf11b)
  • osteoprotegerin (LOC100037695)
  • tumor necrosis factor receptor superfamily, member 11b (Tnfrsf11b)
  • tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) (Tnfrsf11b)
  • OCIF protein
  • Opg protein
  • TR1 protein

Protein level used designations for TNFRSF11B

osteoprotegerin , tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) , Osteoprotegerin , tumor necrosis factor receptor superfamily, member 11b , tumor necrosis factor receptor superfamily member 11B-like , osteoclastogenesis inhibitory factor , tumor necrosis factor receptor superfamily member 11B

GENE ID SPECIES
464351 Pan troglodytes
444716 Xenopus laevis
482025 Canis lupus familiaris
701850 Macaca mulatta
100399751 Callithrix jacchus
100433420 Pongo abelii
100465761 Ailuropoda melanoleuca
100599407 Nomascus leucogenys
100037695 Ovis aries
4982 Homo sapiens
100348133 Oryctolagus cuniculus
25341 Rattus norvegicus
100860896 Capra hircus
100049688 Sus scrofa
523822 Bos taurus
100065885 Equus caballus
18383 Mus musculus
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