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The protein encoded by TNFRSF11B is a member of the TNF-receptor superfamily. Additionally we are shipping Tumor Necrosis Factor Receptor Superfamily, Member 11b Antibodies (119) and Tumor Necrosis Factor Receptor Superfamily, Member 11b Kits (60) and many more products for this protein.
Showing 10 out of 29 products:
Human TNFRSF11B Protein expressed in HEK-293 Cells - ABIN2181847
Tsuda, Goto, Mochizuki, Yano, Kobayashi, Morinaga, Higashio: Isolation of a novel cytokine from human fibroblasts that specifically inhibits osteoclastogenesis. in Biochemical and biophysical research communications 1997
Show all 4 references for ABIN2181847
Human TNFRSF11B Protein expressed in Hi-5 - ABIN666742
Yasuda, Shima, Nakagawa, Yamaguchi, Kinosaki, Mochizuki, Tomoyasu, Yano, Goto, Murakami, Tsuda, Morinaga, Higashio, Udagawa, Takahashi, Suda: Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. in Proceedings of the National Academy of Sciences of the United States of America 1998
Show all 3 references for ABIN666742
Osteoprotegerin reduction seems to play a pivotal role in the progression of arthropathy in hemophilia A.
Recurrent amplification of MYC (show MYC Proteins) and TNFRSF11B in 8q24 is associated with poor survival in patients with gastric cancer.
this study shows that OPG constitutes a novel biomarker with prognostic significance in patients with severe malaria
Overexpression of OPG in OCCM (show LAMC3 Proteins)-30 cells promotes cementoblastic activity
This study demonstrates that clodronate decreases the compression-induced RANKL/OPG (show TNFSF11 Proteins) ratio expressed by human osteoblasts.
OPG and RANKL (show TNFSF11 Proteins) may play an integral role in breast cancer cells homing to the bone environment
This study implicates that osteoprotegerin gene variants may be associated with early-onset severe pre-eclampsia.
In lung cancer, serum OPG levels in the BM and BM- groups were significantly increased compared with healthy controls.
Alendronate stimulated OPG mRNA and protein expression, but not RANKL (show TNFSF11 Proteins) expression, in fibroblasts from patients with aseptic loosening following total hip arthroplasty.
Single nucleotide polymorphisms (SNPs) rs1035798 in RAGE gene, rs2073617 and rs2073618 in TNFRSF11B, and rs3732410 in Golgb1 will be investigated on whether there is an association with hemorrhagic stroke (HS) in Chinese population.
The OPG (show TNFSF11 Proteins) expression levels decreased while those of RANKL (show TNFSF11 Proteins) and RUNX2 (show RUNX2 Proteins) increased during orthodontic tooth movement, which suggested that they play a role in the osteogenesis process and the reconstruction of periodontal tissue.
Low-frequency vibration may promote the osteogenic differentiation capability of BMSC probably through regulating the OPG/RANKL (show TNFSF11 Proteins) mRNA expression.
Regional variation of periosteal activity at the mandibular ramus is regulated by differential expression of osteoprotegerin.
Data show that p38alpha (show MAPK14 Proteins) mitogen-activated protein kinase (show MAPK1 Proteins) (MAPK (show MAPK1 Proteins)) in paired related homeobox 1 (show PRRX1 Proteins) protein (Prx1 (show PRDX1 Proteins)+) bone marrow-derived mesenchymal stromal cells acts to preserve the bone by sustaining osteoprotegerin (OPG) production.
OPG (show TNFSF11 Proteins) expression in chondrocyte increases bone mass in the proximal metaphysis of tibiae through negative regulation of osteoclast formation.
the generation of Rag2GFP+ regulatory T cells is unaltered in Tnfrsf11b(-/-) mice
identify osteoprotegerin as a HIF target gene capable of directing osteoblast-mediated osteoclastogenesis to regulate bone homeostasis
Osteoprotegerin is increased in metabolic syndrome and promotes adipose tissue proinflammatory changes.
Osteoprotegerin inhibits vascular calcification by regulating the procalcific effects of RANKL (show TNFSF11 Proteins) and Il6 (show IL6 Proteins) on vascular smooth muscle cells.
These results indicate that OPG (show TNFSF11 Proteins) derived either from the bone marrow or from the vessel wall is sufficient to slow down lesion progression and vascular calcification independent of bone turnover.
High concentrations of alendronate decrease the expressions of OPG (show TNFSF11 Proteins) and RANKL (show TNFSF11 Proteins) in cultured osteoblasts.
In a xenograft model, increased osteoprotegerin expression correlated with a delay to pathologic fracture suggesting a potential role for mTOR (show FRAP1 Proteins) inhibitors in the treatment of neuroblastoma (show ARHGEF16 Proteins) bone metastases.
Data indicate in TLR4 (show TLR4 Proteins)(-/-) mice, higher expression levels of IL-1beta (show IL1B Proteins) and lower expression levels of VEGF (show VEGFA Proteins), RANK, RANKL (show TNFSF11 Proteins) and OPG (show TNFSF11 Proteins) were detected at late time points (> postoperative 4 days).
The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
, tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
, tumor necrosis factor receptor superfamily, member 11b
, tumor necrosis factor receptor superfamily member 11B-like
, osteoclastogenesis inhibitory factor
, tumor necrosis factor receptor superfamily member 11B