anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Antibodies

The protein encoded by TNFRSF11B is a member of the TNF-receptor superfamily. Additionally we are shipping Tumor Necrosis Factor Receptor Superfamily, Member 11b Kits (80) and Tumor Necrosis Factor Receptor Superfamily, Member 11b Proteins (41) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TNFRSF11B 4982 O00300
TNFRSF11B 18383 O08712
TNFRSF11B 25341 O08727
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Top anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b Antibodies at antibodies-online.com

Showing 10 out of 174 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB <b>WB Suggested Anti-TNFRSF11B Antibody Titration: </b>1.25ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Mouse Un-conjugated CyTOF, FACS, ICC, IF, IHC, IHC (fro), IHC (p), IP, WB Western blot analysis for OPG with IMG-103A antibody against Daudi cell lysate. Daudi cell lysate blot was incubated with ABIN252469 at a dilution of 1 µg/ml and the immunoreactivity was detected by enhanced chemiluminescence. Flow Cytometry: Osteoprotegerin/TNFRSF11B Antibody (98A1071) [ABIN2524695] - Intracellular staining of 10^6 HeLa cells using 0.2 ug of OPG antibody, 0.5 ul of PE secondary. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Human Mouse Un-conjugated ICC, FACS, ELISA, WB Figure 1: Flow cytometric analysis of HL-60 cells using TNFRSF11B mouse mAb (green) and negative control (purple) . Figure 2: Immunofluorescence analysis of HL-60 cells using TNFRSF11B mouse mAb (green) . Blue: DRAQ5 fluorescent DNA dye. 100 μL Log in to see 2 to 3 Days
$393.80
Details
Human Mouse Un-conjugated IHC, ELISA, WB Figure 1: Immunohistochemical analysis of paraffin-embedded mammary cancer tissues (left) and lung cancer tissues (right) using TNFRSF11B mouse mAb with DAB staining. Figure 2: Western blot analysis using TNFRSF11B mAb against HEK293 (1) and TNFRSF11B (AA: 22-401) -hIgGFc transfected HEK293 (2) cell lysate. 100 μL Log in to see 2 to 3 Days
$393.80
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Confocal immunofluorescent analysis of TNFRSF11B Antibody (Center) (ABIN657660) with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Rabbit Un-conjugated IHC, ELISA, WB Osteoprotegerin staining of rat articular cartilage disk. Paraffin-embedded rat articular cartilage disk tissue is stained with Osteoprotegerin Antibody used at 1:200 dilution. 0.1 mg Log in to see 2 to 6 Days
$327.00
Details
Human Mouse Un-conjugated EIA, WB   0.1 mg Log in to see 6 to 8 Days
$478.50
Details
Human Rabbit Un-conjugated IF, IHC, WB Western blot analysis of extracts of various cell lines, using TNFRSF11B antibody. Immunohistochemistry of paraffin-embedded human stomach cancer using TNFRSF11B antibody at dilution of 1:200 (x400 lens) 100 μL Log in to see 16 Days
$323.13
Details
Human Mouse Un-conjugated IHC (p), WB Human Heart (formalin-fixed, paraffin-embedded) stained with TNFRSF11B antibody ABIN296455 at 5 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. Human Liver (formalin-fixed, paraffin-embedded) stained with TNFRSF11B antibody ABIN296455 at 5 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$451.00
Details

TNFRSF11B Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b Antibodies

  1. Human Monoclonal TNFRSF11B Primary Antibody for CyTOF, FACS - ABIN252469 : Kobayashi, Hashimoto, Miyamoto, Kanaoka, Miyazaki-Kawashita, Nakashima, Shibata, Kobayashi, Kato, Sakai: Force-induced osteoclast apoptosis in vivo is accompanied by elevation in transforming growth factor beta and osteoprotegerin expression. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001 (PubMed)
    Show all 25 Pubmed References

  2. Cow (Bovine) Polyclonal TNFRSF11B Primary Antibody for IHC, ELISA - ABIN1582232 : Fradet, Sorel, Bouazza, Goehrig, Dépalle, Bellahcène, Castronovo, Follet, Descotes, Aubin, Clézardin, Bonnelye: Dual function of ERRα in breast cancer and bone metastasis formation: implication of VEGF and osteoprotegerin. in Cancer research 2011 (PubMed)
    Show all 2 Pubmed References

  3. Human Monoclonal TNFRSF11B Primary Antibody for ICC, FACS - ABIN969439 : Golledge, Biros, Clancy, Cooper, Palmer, Norman: A single-nucleotide polymorphism in the gene encoding osteoprotegerin is associated with diastolic blood pressure in older men. in American journal of hypertension 2009 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal TNFRSF11B Primary Antibody for IHC, ELISA - ABIN969440 : Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ... in American journal of human genetics 2009 (PubMed)
    Show all 2 Pubmed References

  5. Human Monoclonal TNFRSF11B Primary Antibody for ELISA, WB - ABIN2475981 : Westheimer: Why nature chose phosphates. in Science (New York, N.Y.) 1987 (PubMed)
    Show all 3 Pubmed References

  6. Human Monoclonal TNFRSF11B Primary Antibody for WB - ABIN2668734 : Sood, Balasubramanian, Higham, Fernando, Harrison: Osteoprotegerin (OPG) and related proteins (RANK, RANKL and TRAIL) in thyroid disease. in World journal of surgery 2011 (PubMed)

More Antibodies against Tumor Necrosis Factor Receptor Superfamily, Member 11b Interaction Partners

Human Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. Formulation and in vitro and in vivo evaluation of a new osteoprotegerin-chitosan gel for bone tissue regeneration

  2. The RANKL/OPG (show TNFSF11 Antibodies) ratio significantly increased in the presence of bone metastasis with appropriate sensitivity and specificity (73% and 72%, respectively) at a cutoff of >/=0.14 for the detection of bone metastasis. Serum OPG and RANKL/OPG (show TNFSF11 Antibodies) ratios are promising biomarkers for detecting bone metastasis in breast cancer patients.

  3. Osteoprotegerin facilitates pulmonary arterial hypertension pathogenesis by regulating pulmonary arterial smooth muscle cell proliferation via integrin alphavbeta3 (show ITGAV Antibodies)/FAK (show PTK2 Antibodies)/AKT (show AKT1 Antibodies) signaling pathway.

  4. Elevated osteoprotegerin concentration is associated with an increased risk of incident cardiovascular disease in the general population

  5. Physical activity does not increase circulating osteoprotegerin level.

  6. OPG may be a potential driver of lung cancer cells and therefore might have potential in therapy and diagnostics.

  7. our findings suggest OPG is a downstream effector of IL1B (show IL1B Antibodies)-mediated invasion in breast cancer cells.

  8. measurement of serum osteoprotegerin concentration might be useful as a surrogate marker for determining bone loss in patients with chronic kidney disease, especially for women, although not so much for men.

  9. In patients with tightly controlled rheumatoid arthritis, serum OPG was inversely associated with progression of joint destruction.

  10. estrogen may post-transcriptionally regulate OPG expression through suppression of miR (show MLXIP Antibodies)-145 expression.

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. RANK/RANKL (show TNFSF11 Antibodies) signaling is involved in the androgen deprivation therapy-induced acceleration of bone metastasis in castration-insensitive prostate cancer and is inhibited by osteoprotegerin to prevent bone metastasis.

  2. endocortical resorption is driven by reduced OPG (show TNFSF11 Antibodies) rather than elevated RANKL (show TNFSF11 Antibodies) expression

  3. Diabetes significantly increased OPG (show TNFSF11 Antibodies) and the OPG (show TNFSF11 Antibodies)/TRAIL ratio expression in the aorta, while dyslipidemia was the major determinant of the changes observed in the heart, where it significantly increased OPG (show TNFSF11 Antibodies) and reduced TRAIL expression, thus increasing cardiac OPG (show TNFSF11 Antibodies)/TRAIL ratio.

  4. These discoveries strongly suggest that Heparan Sulfate plays an active role in regulating OPG-RANKL (show TNFSF11 Antibodies) interaction and osteoclastogenesis.

  5. OPG (show TNFSF11 Antibodies) plays an important role in regulating bone marrow mesenchymal stem cells differentiation and bone marrow adipogenesis.

  6. These data suggested that OPG (show TNFSF11 Antibodies) played an important role in maintaining the homeostasis of articular cartilage of femoral head.

  7. Data show that p38alpha (show MAPK14 Antibodies) mitogen-activated protein kinase (show MAPK1 Antibodies) (MAPK (show MAPK1 Antibodies)) in paired related homeobox 1 (show PRRX1 Antibodies) protein (Prx1 (show PRDX1 Antibodies)+) bone marrow-derived mesenchymal stromal cells acts to preserve the bone by sustaining osteoprotegerin (OPG) production.

  8. OPG (show TNFSF11 Antibodies) expression in chondrocyte increases bone mass in the proximal metaphysis of tibiae through negative regulation of osteoclast formation.

  9. the generation of Rag2GFP+ regulatory T cells is unaltered in Tnfrsf11b(-/-) mice

  10. identify osteoprotegerin as a HIF target gene capable of directing osteoblast-mediated osteoclastogenesis to regulate bone homeostasis

Rabbit Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. The OPG (show TNFSF11 Antibodies) expression levels decreased while those of RANKL (show TNFSF11 Antibodies) and RUNX2 (show RUNX2 Antibodies) increased during orthodontic tooth movement, which suggested that they play a role in the osteogenesis process and the reconstruction of periodontal tissue.

  2. Low-frequency vibration may promote the osteogenic differentiation capability of BMSC probably through regulating the OPG/RANKL (show TNFSF11 Antibodies) mRNA expression.

Pig (Porcine) Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. Regional variation of periosteal activity at the mandibular ramus is regulated by differential expression of osteoprotegerin.

Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Antigen Profile

Protein Summary

Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis (By similarity).

Gene names and symbols associated with TNFRSF11B

  • tumor necrosis factor receptor superfamily, member 11b (TNFRSF11B) antibody
  • basic transcription factor 3 pseudogene 11 (BTF3P11) antibody
  • tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) (Tnfrsf11b) antibody
  • tumor necrosis factor receptor superfamily, member 11b (Tnfrsf11b) antibody
  • osteoprotegerin (LOC100037695) antibody
  • tumor necrosis factor receptor superfamily, member 11b (tnfrsf11b) antibody
  • BTF3L1 antibody
  • HUMBTFB antibody
  • ocif antibody
  • opg antibody
  • TNFRSF11B antibody
  • tr1 antibody

Protein level used designations for TNFRSF11B

osteoclastogenesis inhibitory factor , osteoprotegerin , tumor necrosis factor receptor superfamily member 11B , Osteoprotegerin , tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) , tumor necrosis factor receptor superfamily, member 11b , tumor necrosis factor receptor superfamily member 11B-like

GENE ID SPECIES
4982 Homo sapiens
690 Homo sapiens
18383 Mus musculus
25341 Rattus norvegicus
464351 Pan troglodytes
523822 Bos taurus
100037695 Ovis aries
444716 Xenopus laevis
482025 Canis lupus familiaris
701850 Macaca mulatta
100399751 Callithrix jacchus
100433420 Pongo abelii
100465761 Ailuropoda melanoleuca
100599407 Nomascus leucogenys
100348133 Oryctolagus cuniculus
100049688 Sus scrofa
100860896 Capra hircus
100065885 Equus caballus
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