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anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Antibodies

The protein encoded by TNFRSF11B is a member of the TNF-receptor superfamily. Additionally we are shipping Tumor Necrosis Factor Receptor Superfamily, Member 11b Kits (70) and Tumor Necrosis Factor Receptor Superfamily, Member 11b Proteins (27) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TNFRSF11B 4982 O00300
TNFRSF11B 25341 O08727
TNFRSF11B 18383 O08712
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Top anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b Antibodies at antibodies-online.com

Showing 10 out of 117 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated CyTOF, FACS, ICC, IF, IHC, IHC (fro), IHC (p), IP, WB Western blot analysis for OPG with IMG-103A antibody against Daudi cell lysate. Daudi cell lysate blot was incubated with ABIN252469 at a dilution of 1 µg/ml and the immunoreactivity was detected by enhanced chemiluminescence. Flow Cytometry: Osteoprotegerin/TNFRSF11B Antibody (98A1071) [ABIN2524695] - Intracellular staining of 10^6 HeLa cells using 0.2 ug of OPG antibody, 0.5 ul of PE secondary. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Cow Rabbit Un-conjugated IHC, ELISA, WB Osteoprotegerin staining of rat articular cartilage disk. Paraffin-embedded rat articular cartilage disk tissue is stained with Osteoprotegerin Antibody used at 1:200 dilution. 0.1 mg Log in to see 2 to 6 Days
$327.00
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated EIA, WB   0.1 mg Log in to see 6 to 8 Days
$478.50
Details
Human Mouse Un-conjugated IHC (p), WB Human Heart (formalin-fixed, paraffin-embedded) stained with TNFRSF11B antibody ABIN296455 at 5 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. Human Liver (formalin-fixed, paraffin-embedded) stained with TNFRSF11B antibody ABIN296455 at 5 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Mouse Un-conjugated EIA, WB   0.1 mg Log in to see 6 to 8 Days
$478.50
Details
Human Mouse Un-conjugated WB   0.1 mg Log in to see 6 to 7 Days
$346.50
Details
Human Mouse Un-conjugated EIA, FACS, IF, WB 0.1 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of Osteoprotegerin staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of Osteoprotegerin staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
$487.50
Details

TNFRSF11B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine)


Top referenced anti-Tumor Necrosis Factor Receptor Superfamily, Member 11b Antibodies

  1. Human Monoclonal TNFRSF11B Primary Antibody for CyTOF, FACS - ABIN252469 : Kobayashi, Hashimoto, Miyamoto, Kanaoka, Miyazaki-Kawashita, Nakashima, Shibata, Kobayashi, Kato, Sakai: Force-induced osteoclast apoptosis in vivo is accompanied by elevation in transforming growth factor beta and osteoprotegerin expression. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001 (PubMed)
    Show all 25 references for ABIN252469

  2. Human Monoclonal TNFRSF11B Primary Antibody for WB - ABIN108499 : Simonet, Lacey, Dunstan, Kelley, Chang, Lüthy, Nguyen, Wooden, Bennett, Boone, Shimamoto, DeRose, Elliott, Colombero, Tan, Trail, Sullivan, Davy, Bucay, Renshaw-Gegg, Hughes, Hill, Pattison, Campbell et al.: Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. ... in Cell 1997 (PubMed)
    Show all 5 references for ABIN108499

  3. Human Monoclonal TNFRSF11B Primary Antibody for EIA, WB - ABIN114706 : Bolten, Weissbach, Kaden: [Cryopreserved human sperm deposits: usability after decades of storage] in Der Urologe. Ausg. A 2005 (PubMed)
    Show all 3 references for ABIN114706

  4. Human Monoclonal TNFRSF11B Primary Antibody for EIA, WB - ABIN114693 : Yasuda, Shima, Nakagawa, Mochizuki, Yano, Fujise, Sato, Goto, Yamaguchi, Kuriyama, Kanno, Murakami, Tsuda, Morinaga, Higashio: Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG): a mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitro. in Endocrinology 1998 (PubMed)
    Show all 3 references for ABIN114693

  5. Cow (Bovine) Polyclonal TNFRSF11B Primary Antibody for IHC, ELISA - ABIN1582232 : Fradet, Sorel, Bouazza, Goehrig, Dépalle, Bellahcène, Castronovo, Follet, Descotes, Aubin, Clézardin, Bonnelye: Dual function of ERRα in breast cancer and bone metastasis formation: implication of VEGF and osteoprotegerin. in Cancer research 2011 (PubMed)
    Show all 2 references for ABIN1582232

  6. Human Monoclonal TNFRSF11B Primary Antibody for EIA, IHC (p) - ABIN1108535 : Golledge, Biros, Clancy, Cooper, Palmer, Norman: A single-nucleotide polymorphism in the gene encoding osteoprotegerin is associated with diastolic blood pressure in older men. in American journal of hypertension 2009 (PubMed)
    Show all 2 references for ABIN1108535

  7. Human Monoclonal TNFRSF11B Primary Antibody for EIA, FACS - ABIN1108534 : Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ... in American journal of human genetics 2009 (PubMed)
    Show all 2 references for ABIN1108534

More Antibodies against Tumor Necrosis Factor Receptor Superfamily, Member 11b Interaction Partners

Human Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. measurement of serum osteoprotegerin concentration might be useful as a surrogate marker for determining bone loss in patients with chronic kidney disease, especially for women, although not so much for men.

  2. In patients with tightly controlled rheumatoid arthritis, serum OPG was inversely associated with progression of joint destruction.

  3. estrogen may post-transcriptionally regulate OPG expression through suppression of miR (show MLXIP Antibodies)-145 expression.

  4. TNFRSF11B mutation is associated with Juvenile Paget's disease.

  5. Review: OPG, RANKL (show TNFSF11 Antibodies) and TRAIL are involved in vascular calcification.

  6. we report the involvement of OPG in cellular and molecular changes in MVP (show MVP Antibodies) isolated cells. In addition, we detected elevated circulating OPG levels in MVP (show MVP Antibodies) patients when compared to controls, which supports the hypothesis that OPG is involved in MVP (show MVP Antibodies) development and progression.

  7. Our results suggest that the polymorphism of the RANKL (show TNFSF11 Antibodies), RANK, and OPG genes does not make a significant genetic contribution to heel ultrasound measurements in a population of young Caucasian adults. Further studies replicating the results in independent populations are needed to support these initial findings.

  8. The study results showed that people carrying the CC genotype of rs2073618 were more likely to have peri (show PLIN1 Antibodies)-implantitis than GG genotype carriers (OR=2.18). Patients with the C allele had 1.47 times the risk of suffering from peri (show PLIN1 Antibodies)-implantitis (OR=1.47), but not rs2073617 polymorphism. The G-C haplotype frequency of rs2073618-rs2073617 in OPG was significantly correlated to the increased susceptibility of peri (show PLIN1 Antibodies)-implantitis.

  9. OPG rs2073618, RANK rs75404003, and RANKL (show TNFSF11 Antibodies) rs9594782 single nucleotide poymorphisms may predispose LVH in thalassemia patients.

  10. The expression for RANKL (show TNFSF11 Antibodies) and OPG and the RANKL/OPG (show TNFSF11 Antibodies) ratio were not significantly different between symptomatic and asymptomatic periapical lesions.

Rabbit Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. The OPG (show TNFSF11 Antibodies) expression levels decreased while those of RANKL (show TNFSF11 Antibodies) and RUNX2 (show RUNX2 Antibodies) increased during orthodontic tooth movement, which suggested that they play a role in the osteogenesis process and the reconstruction of periodontal tissue.

  2. Low-frequency vibration may promote the osteogenic differentiation capability of BMSC probably through regulating the OPG/RANKL (show TNFSF11 Antibodies) mRNA expression.

Pig (Porcine) Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. Regional variation of periosteal activity at the mandibular ramus is regulated by differential expression of osteoprotegerin.

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. endocortical resorption is driven by reduced OPG (show TNFSF11 Antibodies) rather than elevated RANKL (show TNFSF11 Antibodies) expression

  2. Diabetes significantly increased OPG (show TNFSF11 Antibodies) and the OPG (show TNFSF11 Antibodies)/TRAIL ratio expression in the aorta, while dyslipidemia was the major determinant of the changes observed in the heart, where it significantly increased OPG (show TNFSF11 Antibodies) and reduced TRAIL expression, thus increasing cardiac OPG (show TNFSF11 Antibodies)/TRAIL ratio.

  3. These discoveries strongly suggest that Heparan Sulfate plays an active role in regulating OPG-RANKL (show TNFSF11 Antibodies) interaction and osteoclastogenesis.

  4. OPG (show TNFSF11 Antibodies) plays an important role in regulating bone marrow mesenchymal stem cells differentiation and bone marrow adipogenesis.

  5. These data suggested that OPG (show TNFSF11 Antibodies) played an important role in maintaining the homeostasis of articular cartilage of femoral head.

  6. Data show that p38alpha (show MAPK14 Antibodies) mitogen-activated protein kinase (show MAPK1 Antibodies) (MAPK (show MAPK1 Antibodies)) in paired related homeobox 1 (show PRRX1 Antibodies) protein (Prx1 (show PRDX1 Antibodies)+) bone marrow-derived mesenchymal stromal cells acts to preserve the bone by sustaining osteoprotegerin (OPG) production.

  7. OPG (show TNFSF11 Antibodies) expression in chondrocyte increases bone mass in the proximal metaphysis of tibiae through negative regulation of osteoclast formation.

  8. the generation of Rag2GFP+ regulatory T cells is unaltered in Tnfrsf11b(-/-) mice

  9. identify osteoprotegerin as a HIF target gene capable of directing osteoblast-mediated osteoclastogenesis to regulate bone homeostasis

  10. Osteoprotegerin is increased in metabolic syndrome and promotes adipose tissue proinflammatory changes.

Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

Gene names and symbols associated with TNFRSF11B

  • tumor necrosis factor receptor superfamily, member 11b (TNFRSF11B) antibody
  • tumor necrosis factor receptor superfamily, member 11b (tnfrsf11b) antibody
  • osteoprotegerin (LOC100037695) antibody
  • tumor necrosis factor receptor superfamily, member 11b (Tnfrsf11b) antibody
  • tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) (Tnfrsf11b) antibody
  • OCIF antibody
  • Opg antibody
  • TR1 antibody

Protein level used designations for TNFRSF11B

osteoprotegerin , tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) , Osteoprotegerin , tumor necrosis factor receptor superfamily, member 11b , tumor necrosis factor receptor superfamily member 11B-like , osteoclastogenesis inhibitory factor , tumor necrosis factor receptor superfamily member 11B

GENE ID SPECIES
464351 Pan troglodytes
444716 Xenopus laevis
482025 Canis lupus familiaris
701850 Macaca mulatta
100399751 Callithrix jacchus
100433420 Pongo abelii
100465761 Ailuropoda melanoleuca
100599407 Nomascus leucogenys
100037695 Ovis aries
4982 Homo sapiens
100348133 Oryctolagus cuniculus
25341 Rattus norvegicus
100860896 Capra hircus
100049688 Sus scrofa
523822 Bos taurus
100065885 Equus caballus
18383 Mus musculus
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