Tumor Necrosis Factor Receptor Superfamily, Member 13B Proteins (TNFRSF13B)

The protein encoded by TNFRSF13B is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. Additionally we are shipping TNFRSF13B Antibodies (173) and TNFRSF13B Kits (20) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TNFRSF13B 23495 O14836
TNFRSF13B 57916 Q9ET35
Rat TNFRSF13B TNFRSF13B 691719  
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Top TNFRSF13B Proteins at antibodies-online.com

Showing 10 out of 23 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human Fc Tag   50 μg Log in to see 5 to 8 Days
$336.00
Details
HOST_Human Cells Human His tag 100 μg Log in to see 20 to 21 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$319.00
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,244.78
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Escherichia coli (E. coli) Mouse Fc Tag   10 μg Log in to see 10 to 12 Days
$135.88
Details
HOST_Mammalian Cells Human His tag   50 μg Log in to see 4 Days
$313.50
Details
HOST_Mammalian Cells Mouse Fc Tag   50 μg Log in to see 4 Days
$329.18
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 2 to 3 Days
$815.00
Details
HOST_HEK293 Human His-DYKDDDDK-Strep II Tag 2 μg Log in to see 11 to 12 Days
$673.68
Details

TNFRSF13B Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
, , ,
Mouse (Murine) , , , ,
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Top referenced TNFRSF13B Proteins

  1. Mouse (Murine) TNFRSF13B Protein expressed in Escherichia coli (E. coli) - ABIN2667577 : He, Santamaria, Xu, Cols, Chen, Puga, Shan, Xiong, Bussel, Chiu, Puel, Reichenbach, Marodi, Döffinger, Vasconcelos, Issekutz, Krause, Davies, Li, Grimbacher, Plebani, Meffre, Picard et al.: The transmembrane activator TACI triggers immunoglobulin class switching by activating B cells through the adaptor MyD88. ... in Nature immunology 2010 (PubMed)
    Show all 6 references for 2667577

  2. Human TNFRSF13B Protein expressed in Human Cells - ABIN2004906 : Wu, Bressette, Carrell, Kaufman, Feng, Taylor, Gan, Cho, Garcia, Gollatz, Dimke, LaFleur, Migone, Nardelli, Wei, Ruben, Ullrich, Olsen, Kanakaraj, Moore, Baker: Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS. in The Journal of biological chemistry 2000 (PubMed)
    Show all 4 references for 2004906

  3. Human TNFRSF13B Protein expressed in Escherichia coli (E. coli) - ABIN1098781 : von Bülow, Bram: NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor receptor superfamily. in Science (New York, N.Y.) 1997 (PubMed)
    Show all 2 references for 1098781

  4. Human TNFRSF13B Protein expressed in HEK-293 Cells - ABIN1344232 : Huard, Tran, Benkhoucha, Manzin-Lorenzi, Santiago-Raber: Selective APRIL blockade delays systemic lupus erythematosus in mouse. in PLoS ONE 2012 (PubMed)

More Proteins for Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B) Interaction Partners

Human Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B) interaction partners

  1. results suggest that TACI A181E heterozygosity results in TACI haploinsufficiency with increased susceptibility to pneumococcal infection

  2. The expression levels of serum BAFF (show TNFSF13B Proteins) and the three receptors (TACI, BCMA (show TNFRSF17 Proteins) and BAFF-R (show TNFRSF13C Proteins)) in non-Hodgkin lymphoma patients were significantly higher than in healthy controls.

  3. 11% of common variable immunodeficiency patients and 13% of antibody deficiency syndromes patients carried at least one mutated TNFRSF13B allele.

  4. SNPs rs9514828 (BAFF (show TNFSF13B Proteins)), rs3803800 (APRIL) and rs4985726 (TACI) may be associated with the risk of development of B-cell chronic lymphocytic leukemia in a Polish population.

  5. serum levels not associated with disease activity in MPO (show MPO Proteins)-ANCA-associated renal vasculitis

  6. In this review, we aim at giving an insight into the genetics underlying the CVID and particularly at outlining the role of TACI and its relative contribution to the development of CVID-like phenotypes in human.

  7. TNFRSF13B hemizygosity does not recapitulate autoimmune features of common variable immune deficiency -associated C104R and A181E TNFRSF13B mutations, which likely encode dominant negative products, but instead reveals selective TACI haploinsufficiency at later stages of B-cell development.

  8. Common variable immune d (show TNFSF13B Proteins)eficiency patients with heterozygous mutations in TACI alleles increase susceptibility to autoimmune diseases.

  9. The study demonstrated that there is a remarkable interindividual variability of TACI expression in chronic lymphocytic leukemia, although the majority of patients display low to undetectable TACI.

  10. Variants of TNFRSF13B were associated with common variable immunodeficiency.

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 13B (TNFRSF13B) interaction partners

  1. findings highlight a novel mechanism through which BAFF (show TNFSF13B Proteins) promotes humoral autoimmunity via direct, TACI-dependent activation of transitional B cells

  2. results suggest that TACI A181E heterozygosity results in TACI haploinsufficiency with increased susceptibility to pneumococcal infection

  3. this study shows that increased TACI expression in B cells derived from non-obese diabetic mice contributes to the pathogenesis of type 1 diabetes NOD mice

  4. splenic B cells from TACI-deficient (TACI- / -) mice were unable to secrete IL-10 (show IL10 Proteins) following TLR stimulation, and TACI- / - mice had undetectable basal serum concentrations of IL-10 (show IL10 Proteins).

  5. Data show that production of autoantibodies in B cell-activating factor (show TNFSF13B Proteins) of the TNF (show TNF Proteins) family (BAFF (show TNFSF13B Proteins)) is dependent on tumor necrosis factor (show TNF Proteins) receptor superfamily, member 13b protein (TACI) expression by B cells.

  6. Taci (-/-) mice and BAFF (show TNFSF13B Proteins) transgenic mice both develop signs of human Systemic Lupus Erythematosus.

  7. Elimination of B lymphocyte stimulator (show TNFSF13B Proteins) receptor 3 (BR-3) and TACI inhibits the development of SLE in NZM mice.

  8. TACI deficiency has a role in alternatively activated macrophage phenotype and susceptibility to Leishmania infection

  9. Heteromers consisting of one BAFF (show TNFSF13B Proteins) and two APRIL bind to receptor TACI, BCMA (show TNFRSF17 Proteins) but not to BAFFR (show TNFRSF13C Proteins).

  10. Mice lacking TACI are able to clear Citrobacter rodentium, a model pathogen for severe human enteritis, more rapidly than did wild type mice.

TNFRSF13B Protein Profile

Protein Summary

The protein encoded by this gene is a lymphocyte-specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein induces activation of the transcription factors NFAT, AP1, and NF-kappa-B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith-Magenis syndrome region on chromosome 17.

Gene names and symbols associated with TNFRSF13B

  • tumor necrosis factor receptor superfamily, member 13B (TNFRSF13B)
  • tumor necrosis factor receptor superfamily, member 13b (Tnfrsf13b)
  • tumor necrosis factor receptor superfamily, member 13B (Tnfrsf13b)
  • 1200009E08Rik protein
  • CD267 protein
  • CVID protein
  • CVID2 protein
  • RYZN protein
  • Taci protein
  • TNFRSF13B protein
  • TNFRSF14B protein

Protein level used designations for TNFRSF13B

tumor necrosis factor receptor superfamily, member 13B , tumor necrosis factor receptor superfamily member 13B , transmembrane activator and CAML interactor , tumor necrosis factor receptor 13B , transmembrane activator and calcium-modulating and cyclophilin ligand interactor

GENE ID SPECIES
609580 Canis lupus familiaris
617948 Bos taurus
744388 Pan troglodytes
770275 Gallus gallus
23495 Homo sapiens
57916 Mus musculus
691719 Rattus norvegicus
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