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Tumor Necrosis Factor Receptor Superfamily, Member 17 Proteins (TNFRSF17)

The protein encoded by TNFRSF17 is a member of the TNF-receptor superfamily. Additionally we are shipping TNFRSF17 Antibodies (108) and TNFRSF17 Kits (15) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TNFRSF17 287034  
TNFRSF17 608 Q02223
TNFRSF17 21935 O88472
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Top TNFRSF17 Proteins at antibodies-online.com

Showing 10 out of 40 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Human Fc Tag   50 μg Log in to see 5 to 8 Days
$351.75
Details
HOST_HEK-293 Cells Human Fc Tag 100 μg Log in to see 2 to 3 Days
$275.00
Details
HOST_Human Cells Cynomolgus Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Human Cells Rat Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Human Cells Mouse His tag,Fc Tag 100 μg Log in to see 16 Days
$382.80
Details

TNFRSF17 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Human , , , , , ,
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Mouse (Murine) , , ,
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Top referenced TNFRSF17 Proteins

  1. Human TNFRSF17 Protein expressed in Human - ABIN1344234 : Rennert, Schneider, Cachero, Thompson, Trabach, Hertig, Holler, Qian, Mullen, Strauch, Browning, Ambrose, Tschopp: A soluble form of B cell maturation antigen, a receptor for the tumor necrosis factor family member APRIL, inhibits tumor cell growth. in The Journal of experimental medicine 2000 (PubMed)
    Show all 4 references for ABIN1344234

  2. Human TNFRSF17 Protein expressed in HEK-293 Cells - ABIN2180644 : Gross, Johnston, Mudri, Enselman, Dillon, Madden, Xu, Parrish-Novak, Foster, Lofton-Day, Moore, Littau, Grossman, Haugen, Foley, Blumberg, Harrison, Kindsvogel, Clegg: TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease. in Nature 2000 (PubMed)
    Show all 4 references for ABIN2180644

  3. Human TNFRSF17 Protein expressed in Escherichia coli (E. coli) - ABIN1098476 : Barone, Patel, Sanderson, Spencer: Gut-associated lymphoid tissue contains the molecular machinery to support T-cell-dependent and T-cell-independent class switch recombination. in Mucosal immunology 2009 (PubMed)
    Show all 2 references for ABIN1098476

  4. Rat (Rattus) TNFRSF17 Protein expressed in Human Cells - ABIN2009225 : Liu, Hong, Kappler, Jiang, Zhang, Xu, Pan, Martin, Murphy, Shu, Dai, Zhang: Ligand-receptor binding revealed by the TNF family member TALL-1. in Nature 2003 (PubMed)
    Show all 2 references for ABIN2009225

  5. Cynomolgus TNFRSF17 Protein expressed in Human Cells - ABIN2009845 : Hymowitz, Patel, Wallweber, Runyon, Yan, Yin, Shriver, Gordon, Pan, Skelton, Kelley, Starovasnik: Structures of APRIL-receptor complexes: like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding. in The Journal of biological chemistry 2005 (PubMed)
    Show all 2 references for ABIN2009845

More Proteins for Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) Interaction Partners

Human Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) interaction partners

  1. shedding of BCMA by gamma-secretase controls plasma cells in the bone marrow and yields a potential biomarker for B-cell involvement in human autoimmune diseases

  2. Data show significant differences in expression of tumour necrosis factor (show TNF Proteins) family (BAFF (show TNFSF13B Proteins)) receptors BAFF-R (show TNFRSF13C Proteins), BCMA and TACI (show TNFRSF13B Proteins) in patients with and without anti-Jo-1 or anti-Ro52 (show TRIM21 Proteins)/anti-Ro60 (show TROVE2 Proteins) autoantibodies.

  3. High BCMA expression is associated with breast cancer.

  4. BAFF (show TNFSF13B Proteins) and APRIL as well as their cognate receptors (BCMA, TACI (show TNFRSF13B Proteins)) correlate with glioma grade. (Meta-analysis)

  5. The B cell maturation antigen (BCMA) is a tumor necrosis family receptor member that is predominantly expressed on terminally differentiated B cells and, upon binding to its ligands B cell activator of the TNF (show TNF Proteins) family and a proliferation inducing ligand (show TNFSF13 Proteins).

  6. Activation of B cells through BCMA regulates spinal cord injury-induced autoimmunity via a proliferation-inducing ligand (show TNFSF13 Proteins) (APRIL) and B-cell-activating factor (BAFF (show TNFSF13B Proteins)).

  7. Data indicate that MAGE3 (show MAGEA3 Proteins), Survivin (show BIRC5 Proteins) and B-cell maturation antigen (BCMA) mRNA-pulsed dendritic cells (DCs) are capable of stimulating tumor-associated antigens (TAA)-specific T-cell responses in multiple myeloma (MM) patients.

  8. Data indicate that B-cell maturation antigen (BCMA) is a suitable target for chimeric antigen receptor (CAR)-expressing T cells, and adoptive transfer of anti-BCMA-CAR-expressing T cells is a promising new strategy for treating multiple myeloma.

  9. B-cell maturation antigen (BCMA), an essential membrane protein for maintaining the survival of plasma cells, was identified as a glycoprotein exhibiting complex-type N-glycans at a single N-glycosylation site, asparagine 42.

  10. the effect of APRIL is mediated via BCMA, which does not activate the classical NF-kappaB (show NFKB1 Proteins) pathway, whereas it induces a novel signaling pathway, which involves JNK2 (show MAPK9 Proteins) phosphorylation, FOXO3A (show FOXO3 Proteins) activation, and GADD45 (show GADD45A Proteins) transcription

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 17 (TNFRSF17) interaction partners

  1. high affinity antibody blocks the binding of the native ligands APRIL and BAFF (show TNFSF13B Proteins) to BCMA. This finding is rationalized by the high resolution crystal structure of the Fab (show FANCB Proteins) fragment in complex with the extracellular domain of BCMA

  2. Elimination of B lymphocyte stimulator (show TNFSF13B Proteins) receptor 3 (BR-3) and BCMA inhibits the development of SLE in NZM mice.

  3. we have identified a novel role for BCMA to control excess BAFF (show TNFSF13B Proteins) production in murine lupus through restraining the accumulation of BAFF (show TNFSF13B Proteins)-producing neutrophils.

  4. Heteromers consisting of one BAFF (show TNFSF13B Proteins) and two APRIL bind to receptor TACI (show TNFRSF13B Proteins), BCMA but not to BAFFR (show TNFRSF13C Proteins).

  5. BCMA is dispensable for the development of SLE in NZM mice. BAFF (show TNFSF13B Proteins)-BCMA interactions contribute to SLE.

  6. Study reveals that BCMA works to control B cell homeostasis and self-tolerance in systemic autoimmunity.

  7. Blimp-1 (show PRDM1 Proteins) is a positive regulator of the expression of BCMA gene in mouse plasma cells.

  8. The 5'-flanking sequence from -820 to +145 bp of BCMA is of promoter activity.

  9. A vital role of BCMA in bone marrow plasma cell survival.

  10. B cell maturation antigen, the receptor for a proliferation-inducing ligand (show TNFSF13 Proteins) and B cell-activating factor (show TNFSF13B Proteins) of the TNF (show TNF Proteins) family, induces antigen presentation in B cells.

TNFRSF17 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.

Gene names and symbols associated with TNFRSF17

  • tumor necrosis factor receptor superfamily, member 17 (Tnfrsf17)
  • tumor necrosis factor receptor superfamily, member 17 (TNFRSF17)
  • BCM protein
  • BCMA protein
  • CD269 protein
  • Tnfrsf13 protein
  • Tnfrsf13a protein
  • TNFRSF17 protein

Protein level used designations for TNFRSF17

tumor necrosis factor receptor superfamily member 17 , tumor necrosis factor receptor superfamily, member 17 , B cell maturation antigen , B-cell maturation factor , B-cell maturation protein

GENE ID SPECIES
287034 Rattus norvegicus
467905 Pan troglodytes
712212 Macaca mulatta
608 Homo sapiens
21935 Mus musculus
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