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Tumor Necrosis Factor Receptor Superfamily, Member 18 Proteins (TNFRSF18)

TNFRSF18 encodes a member of the TNF-receptor superfamily. Additionally we are shipping TNFRSF18 Antibodies (211) and TNFRSF18 Kits (18) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TNFRSF18 21936 O35714
TNFRSF18 8784 Q9Y5U5
TNFRSF18 500598  
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Top TNFRSF18 Proteins at antibodies-online.com

Showing 10 out of 23 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag 100 μg Log in to see 5 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Human Mouse Fc Tag   50 μg Log in to see 5 to 8 Days
$351.75
Details
HOST_Human Human Fc Tag   50 μg Log in to see 5 to 8 Days
$383.25
Details
HOST_Human Cells Human Fc Tag 100 μg Log in to see 16 Days
$250.80
Details
HOST_Human Cells Rat Fc Tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

TNFRSF18 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , , , ,
, , ,
Human , , , , , ,
, , , ,
Rat (Rattus) ,

Top referenced TNFRSF18 Proteins

  1. Human TNFRSF18 Protein expressed in HEK-293 Cells - ABIN2181162 : Gurney, Marsters, Huang, Pitti, Mark, Baldwin, Gray, Dowd, Brush, Heldens, Schow, Goddard, Wood, Baker, Godowski, Ashkenazi: Identification of a new member of the tumor necrosis factor family and its receptor, a human ortholog of mouse GITR. in Current biology : CB 1999 (PubMed)

More Proteins for Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) Interaction Partners

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) interaction partners

  1. GITR appears as a potential target for intervention during infection by the parasite Toxoplasma gondii, even though further studies are still necessary to better characterize the immune response triggered by GITR activation during T. gondii infection

  2. our data suggest a critical role for GITR in Treg cell homeostasis and indicate that Ptpn22 (show PTPN22 Proteins) independently affects the differentiation status of Treg cells and their homeostatic behavior

  3. These findings provide further support for the continued development of agonist anti-GITR antibodies as an immunotherapeutic strategy for osteosarcoma. We suggest that our proposed immunotherapy could be developed further to improve osteosarcoma treatment

  4. Th9 cells and iTregs are developmentally linked and GITR can subvert tolerogenic conditions to boost Th9 immunity.

  5. GITR is a crucial player in differentiation of thymic regulatory T cells and expansion of regulatory T cells, including both thymic regulatory T cells and peripheral regulatory T cells.

  6. enhanced GITR-triggering mediates its protective, anti-viral effect on the CD8 (show CD8A Proteins) T cell compartment by boosting CD4 (show CD4 Proteins) T cell help.

  7. A CD4 (show CD4 Proteins) T cell-intrinsic role for GITR in sustaining early CD8 (show CD8A Proteins) and late humoral responses to collectively promote control of chronic LCMV clone 13 infection.

  8. GITRL (show TNFSF18 Proteins) expressed on macrophages drives cytokine release and T cell activation, resulting in neuropathic pain via GITR-dependent actions. The GITRL (show TNFSF18 Proteins)-GITR pathway might represent a novel target for the treatment of neuropathic pain.

  9. Data show that GITR agonist antibody alters Treg lineage stability inducing an inflammatory effector T cell phenotype. The resultant loss of lineage stability causes Treg to lose their intra-tumor immune suppressive function.

  10. Gene expression in the Gitr locus is regulated by NF-kappaB (show NFKB1 Proteins) and Foxp3 (show FOXP3 Proteins) through an enhancer.

Human Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) interaction partners

  1. GITR expression can enhance the sensitivity to Bortezomib by inhibiting Bortezomib-induced NF-kappaB (show NFKB1 Proteins) activation.

  2. GITR is a crucial player in differentiation of thymic regulatory T cells and expansion of regulatory T cells, including both thymic regulatory T cells and peripheral regulatory T cells.

  3. Data may suggest a key role of regulatory GITR+CD25 (show IL2RA Proteins) low/-CD4 (show CD4 Proteins)+ T cells subset in the modulation of the abnormal immune response in lupus erythematosus (SLE) patients.

  4. results suggest that the GITR rs3753348 polymorphism may be involved in the development and susceptibility of CWP.

  5. these results show a higher susceptibility to apoptosis in patients' versus controls' T(reg (show EXTL3 Proteins)) cells, suggesting that GITR is a T(reg (show EXTL3 Proteins))-cell marker that would be primarily involved in T(reg (show EXTL3 Proteins))-cell survival rather than in their suppressor function.

  6. Our findings indicate the possible involvement of GITR-GITRL (show TNFSF18 Proteins) pathway in the pathogenesis of pSS (show CDSN Proteins).

  7. GITR acts as a potential tumor suppressor in MM.

  8. Data indicate that the mRNAs of CTLA-4 (show CTLA4 Proteins) and GITR genes were expressed at lower levels in CVID (show TNFRSF13B Proteins) patients compared to control group.

  9. GITR is pathologically expressed on Treg cells in systemic lupus erythematosus.

  10. Liver tumor Tregs up-regulate the expression of glucocorticoid-induced tumor necrosis factor (show TNF Proteins) receptor compared with Tregs in tumor-free liver tissue and blood.

TNFRSF18 Protein Profile

Protein Summary

This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Gene names and symbols associated with TNFRSF18

  • tumor necrosis factor receptor superfamily, member 18 (TNFRSF18)
  • tumor necrosis factor receptor superfamily, member 18 (Tnfrsf18)
  • AITR protein
  • CD357 protein
  • Gitr protein
  • GITR-D protein
  • TNFRSF18 protein

Protein level used designations for TNFRSF18

tumor necrosis factor receptor superfamily member 18 , glucocorticoid-induced TNFR-related , tumor necrosis factor receptor superfamily, member 18 , glucocorticoid-induced TNFR-related protein , TNF receptor superfamily activation-inducible protein , activation-inducible TNFR family receptor

GENE ID SPECIES
419424 Gallus gallus
516256 Bos taurus
606971 Canis lupus familiaris
699559 Macaca mulatta
741567 Pan troglodytes
21936 Mus musculus
8784 Homo sapiens
500598 Rattus norvegicus
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