Tumor Necrosis Factor Receptor Superfamily, Member 18 Proteins (TNFRSF18)

TNFRSF18 encodes a member of the TNF-receptor superfamily. Additionally we are shipping TNFRSF18 Antibodies (340) and TNFRSF18 Kits (19) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TNFRSF18 21936 O35714
TNFRSF18 8784 Q9Y5U5
TNFRSF18 500598  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top TNFRSF18 Proteins at antibodies-online.com

Showing 10 out of 36 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag Human GITR, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 92%. Immobilized Human GITR, His Tag (Cat# GIR-H5228) at 2 μg/mL (100 μl/well) can bind Human GITR Ligand, Fc Tag (Cat# GIL-H526a ) with a linear range of 0.8-25 ng/mL. 100 μg Log in to see 5 Days
$319.00
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,244.78
Details
HOST_Human Cells Human His tag,ECD 100 μg Log in to see 20 to 21 Days
$250.80
Details
HOST_HEK-293 Cells Rat His tag Rat GITR, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 100 μg Log in to see 5 Days
$319.00
Details
HOST_HEK-293 Cells Mouse Fc Tag   50 μg Log in to see 5 to 8 Days
$351.75
Details
HOST_HEK-293 Cells Human Fc Tag   50 μg Log in to see 5 to 8 Days
$383.25
Details
HOST_HEK-293 Cells Rhesus Monkey Fc Tag Rhesus macaque GITR, Fc Tag on SDS-PAGE under reducing (R) and no-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 100 μg Log in to see 5 Days
$385.00
Details
HOST_Mammalian Cells Mouse Fc Tag,His tag   50 μg Log in to see 4 Days
$313.50
Details
HOST_Human Cells Rat Fc Tag 100 μg Log in to see 20 to 21 Days
$382.80
Details

TNFRSF18 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , , ,
, , ,
Human , , , , ,
, , , , ,
Rat (Rattus) ,
,

More Proteins for Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) Interaction Partners

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) interaction partners

  1. Expression of human GITR was comparable with that of mouse GITR in tumor-infiltrating Tregs despite being drastically lower in other human TILs and in many human peripheral blood populations.

  2. anti-GITR mAb shifts Treg populations to enable immune attack on tumors, with clinical implications for molecular markers to modify emerging treatments.

  3. Continuous GITR stimulation through B cell Gitrl (show TNFSF18 Proteins) acts protective in a mouse model of atherosclerosis by regulating the balance between regulatory and effector memory CD4 (show CD4 Proteins)(+) T cells.

  4. these results indicate that blockade of GITR signaling can ameliorate arthritis progression mainly by modulating the follicular helper T cell response

  5. GITR appears as a potential target for intervention during infection by the parasite Toxoplasma gondii, even though further studies are still necessary to better characterize the immune response triggered by GITR activation during T. gondii infection

  6. our data suggest a critical role for GITR in Treg cell homeostasis and indicate that Ptpn22 (show PTPN22 Proteins) independently affects the differentiation status of Treg cells and their homeostatic behavior

  7. These findings provide further support for the continued development of agonist anti-GITR antibodies as an immunotherapeutic strategy for osteosarcoma. We suggest that our proposed immunotherapy could be developed further to improve osteosarcoma treatment

  8. Th9 cells and iTregs are developmentally linked and GITR can subvert tolerogenic conditions to boost Th9 immunity.

  9. GITR is a crucial player in differentiation of thymic regulatory T cells and expansion of regulatory T cells, including both thymic regulatory T cells and peripheral regulatory T cells.

  10. enhanced GITR-triggering mediates its protective, anti-viral effect on the CD8 (show CD8A Proteins) T cell compartment by boosting CD4 (show CD4 Proteins) T cell help.

Human Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) interaction partners

  1. HTLV-1 infection can modify the expression of main functional transcription factors, FOXP3 (show FOXP3 Proteins) and GITR

  2. a novel molecular mechanism by which MBD4 (show MBD4 Proteins) inhibits GITR expression in a DNMT1 (show DNMT1 Proteins)-dependent manner

  3. Aberrant expression of GITR may contribute to systemic lupus erithematosus pathogenesis. Glucocorticoid may achieve its therapeutic effect partly by inducing GITR expression on Tresps rather than Tregs, which initiates the apoptosis of Tresp cells in SLE patients.

  4. GITR expression can enhance the sensitivity to Bortezomib by inhibiting Bortezomib-induced NF-kappaB (show NFKB1 Proteins) activation.

  5. GITR is a crucial player in differentiation of thymic regulatory T cells and expansion of regulatory T cells, including both thymic regulatory T cells and peripheral regulatory T cells.

  6. Data may suggest a key role of regulatory GITR+CD25 (show IL2RA Proteins) low/-CD4 (show CD4 Proteins)+ T cells subset in the modulation of the abnormal immune response in lupus erythematosus (SLE) patients.

  7. results suggest that the GITR rs3753348 polymorphism may be involved in the development and susceptibility of CWP.

  8. these results show a higher susceptibility to apoptosis in patients' versus controls' T(reg (show EXTL3 Proteins)) cells, suggesting that GITR is a T(reg (show EXTL3 Proteins))-cell marker that would be primarily involved in T(reg (show EXTL3 Proteins))-cell survival rather than in their suppressor function.

  9. Our findings indicate the possible involvement of GITR-GITRL (show TNFSF18 Proteins) pathway in the pathogenesis of pSS (show CDSN Proteins).

  10. GITR acts as a potential tumor suppressor in MM.

TNFRSF18 Protein Profile

Protein Summary

This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Gene names and symbols associated with TNFRSF18

  • tumor necrosis factor receptor superfamily, member 18 (TNFRSF18)
  • tumor necrosis factor receptor superfamily, member 18 (Tnfrsf18)
  • AITR protein
  • CD357 protein
  • Gitr protein
  • GITR-D protein
  • TNFRSF18 protein

Protein level used designations for TNFRSF18

tumor necrosis factor receptor superfamily member 18 , glucocorticoid-induced TNFR-related , tumor necrosis factor receptor superfamily, member 18 , glucocorticoid-induced TNFR-related protein , TNF receptor superfamily activation-inducible protein , activation-inducible TNFR family receptor

GENE ID SPECIES
419424 Gallus gallus
516256 Bos taurus
606971 Canis lupus familiaris
699559 Macaca mulatta
741567 Pan troglodytes
21936 Mus musculus
8784 Homo sapiens
500598 Rattus norvegicus
Selected quality suppliers for TNFRSF18 Proteins (TNFRSF18)
Did you look for something else?