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Involved in calcium binding and microtubule stabilization (By similarity). Additionally we are shipping Tumor Protein, Translationally-Controlled 1 Proteins (49) and Tumor Protein, Translationally-Controlled 1 Kits (20) and many more products for this protein.
Showing 10 out of 155 products:
Human Polyclonal TPT1 Primary Antibody for FACS - ABIN2666237
Bommer, Borovjagin, Greagg, Jeffrey, Russell, Laing, Lee, Clemens: The mRNA of the translationally controlled tumor protein P23/TCTP is a highly structured RNA, which activates the dsRNA-dependent protein kinase PKR. in RNA (New York, N.Y.) 2002
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Human Polyclonal TPT1 Primary Antibody for EIA, IHC (p) - ABIN1449687
Gross, Gaestel, Böhm, Bielka: cDNA sequence coding for a translationally controlled human tumor protein. in Nucleic acids research 1989
Show all 3 references for ABIN1449687
Human Polyclonal TPT1 Primary Antibody for IHC, ELISA - ABIN1533616
Dunham, Matthews, Burton, Ashurst, Howe, Ashcroft, Beare, Burford, Hunt, Griffiths-Jones, Jones, Keenan, Oliver, Scott, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey et al.: The DNA sequence and analysis of human chromosome 13. ... in Nature 2004
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Human Polyclonal TPT1 Primary Antibody for ICC, IF - ABIN408173
Kim, Nam, Li, Park, Lee, Kim, Kim, Kang, Han, Yoo, Han, Kang: Translationally controlled tumour protein is associated with podocyte hypertrophy in a mouse model of type 1 diabetes. in Diabetologia 2012
Human Monoclonal TPT1 Primary Antibody for IF, IP - ABIN967997
MacDonald, Rafnar, Langdon, Lichtenstein: Molecular identification of an IgE-dependent histamine-releasing factor. in Science (New York, N.Y.) 1995
TCTP may promote the progression of epithelial ovarian cancer and reduce the sensitiveness of HO8910 cells to cisplatin.
TCTP has a role in regulating ATM (show ATM Antibodies) activity to control genome stability and organ development in Drosophila melanogaster
Our studies identify TCTP as a direct regulator of Rheb (show RHEB Antibodies) and a potential therapeutic target for tuberous sclerosis disease.
Drosophila TCTP (dTCTP) displays GEF (show SLC2A4RG Antibodies) activity to Rheb (show RHEB Antibodies) and is essential for Rheb (show RHEB Antibodies) activation in organ growth
pretreatment of donor cells with phosphorylated TCTP peptide has a beneficial effect on the potential of bovine somatic cell nuclei to develop into normal cloned calves.
A 'Y' transition single feature polymorphism in TCTP between Meishan and white composite swine breeds was identified by expression profiling using the in silico procedure Click-'N-SNP.
This work describes the cloning and structural analysis of a Tpt1 cDNA coding for the porcine translationally controlled tumor protein (TCTP) molecule and its expression in porcine cells and tissues.
BmTCTP as a dual-functional protein involved in both the cellular and the humoral immune response of the silkworm
TCTP has molecular properties similar to animal TCTPs, such as tubulin (show TUBB Antibodies)- and calcium-binding, and that it functions in ABA-mediated stomatal movement, in addition to regulating the growth of plants.
The results identify TCTP as an important regulator of growth in plants and imply a function of plant TCTP as a mediator of TOR activity similar to that known in nonplant systems.
Downregulation of the expression of TCTP inhibits the migration and invasion of glioma cells.
These data may suggest an involvement of translationally controlled tumor protein in normal physiology and carcinogenesis.
High HRF expression is associated with non-Hodgkin lymphomas.
Results demonstrate that TCTP mRNA translation is regulated by signalling through the PI3-K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies)/mTORC1 pathway in neoplasms.
High phospho-TCTP expression levels are associated with aggressive breast cancer.
TCTP binds to hemin and functions as a "buffer protein", controlling cellular homeostasis.
analysis of how TCTP-PTD (show BCS1L Antibodies) penetrates A549 human lung cancer cell membranes and promotes protein internalization
Data indicate that Tanshinone IIA (Tan-IIA)T upregulated the protein expression of CHOP (show DDIT3 Antibodies) and Bax (show BAX Antibodies), but downregulated the protein expression of BiP (show GDF10 Antibodies), TCTP, Mcl-1 (show MCL1 Antibodies) and Bcl-xL (show BCL2L1 Antibodies).
Targeting Hsp27 (show HSPB1 Antibodies) interaction with TCTP, a partner protein identified in a genetic screen, increases therapy sensitivity, and could decrease or abolish toxicity to normal cells.
TCTP is functionally implicated in the progression of NF1 (show NF1 Antibodies)-associated tumors.
results demonstrate that TCTP is a microtubule-associating protein required to regulate spindle microtubule dynamics during meiotic maturation in mouse oocytes.
TCTP over-expression-induced RhoA (show RHOA Antibodies) activation indicates that silencing of cellular TCTP may offer therapeutic approaches for the regulation of hypertension by inhibiting RhoA (show RHOA Antibodies)/Rho kinase (show ROCK2 Antibodies) pathway and modulating vascular contractility.
osteoclastogenic activity of translationally-controlled tumor protein (TCTP) with reciprocal repression of p21 (show D4S234E Antibodies)
TPT1 is a p53 (show TP53 Antibodies) target gene that promotes cell survival.
Fortilin, induced in the proatherosclerotic microenvironment in macrophages, protects macrophages against Bax (show BAX Antibodies)-induced apoptosis, allows them to propagate, and accelerates atherosclerosis.
Overexpression of translationally controlled tumor protein increases the severity of atherosclerosis and hypertension in apolipoprotein E (show APOE Antibodies) knock-out mice
These findings suggest that TCTP might play an important role in the process of podocyte hypertrophy under diabetic conditions via the regulation of mTORC1 activity and the induction of cell-cycle arrest.
The TCTP downregulates the Oct4 (show POU5F1 Antibodies) expression by binding the Sf1 (show SF1 Antibodies) site of Oct4 (show POU5F1 Antibodies) promoter in mouse pluripotent cells.
TCTP may play a significant role in embryo implantation in mice
knockdown of Tctp resulted in increased amounts of P53 (show TP53 Antibodies) accompanied by a 50% reduction in the efficiency of tumor mammosphere formation
Tctp supports the development of the retinotectal projection via its regulation of pro-survival signalling and axonal mitochondrial homeostasis, and establish a novel and fundamental role for Tctp in vertebrate neural circuitry assembly.
Tpt1 activates transcription of oct4 and nanog in transplanted somatic nuclei.
Involved in calcium binding and microtubule stabilization (By similarity).
translationally-controlled tumor protein homolog
, translationally controlled tumor protein
, tumor protein, translationally-controlled 1
, translationally-controlled tumor protein
, histamine-releasing factor
, 21 kDa polypeptide under translational control
, translationally regulated transcript (21 kDa)
, lens epithelial protein
, growth-related translationally controlled tumor protein
, growth-related translationally-controlled tumor protein
, translationally controlled tumor protein (TCTP)
, translationally controlled tumor protein 3
, translationally controlled tumor protein 4