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anti-Tumor Protein P53 Binding Protein 2 (TP53BP2) Antibodies

TP53BP2 encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. Additionally we are shipping Tumor Protein P53 Binding Protein 2 Kits (5) and Tumor Protein P53 Binding Protein 2 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TP53BP2 21981 Q62415
TP53BP2 7159 Q13625
TP53BP2 305025  
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Top anti-Tumor Protein P53 Binding Protein 2 Antibodies at antibodies-online.com

Showing 10 out of 63 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB TP53BP2 Antibody (N-term) western blot analysis in T47D cell line lysa... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Dog Rabbit Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Human Mouse Un-conjugated IF, WB Western blot analysis of 53BP2 on human endothelial lysate. Lane 1: 1:... Endothelial Cells 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated IHC, ELISA, WB ASPP2 staining in human uterine cancer tissue. Paraffin-embedded human... 0.1 mg Log in to see 2 to 6 Days
$359.70
Details
Human Rabbit Un-conjugated WB TP53BP2 Antibody (N-term)  western blot analysis in T47D cell line lys... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: NT2D1 7.5% SDS PAGE an... 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated ELISA, WB Western blot using Protein A purified anti-ASPP2 to detect over-expres... 100 μg Log in to see 2 to 3 Days
$369.00
Details
Dog Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse lung labeled with Rabbit An... Lane 1: Mouse spleen lysate Lane 2: Mouse thymus lysate Lane 3: Mouse ... 100 μL Log in to see 3 to 7 Days
$269.50
Details

TP53BP2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) , , , ,

Human , , , ,
,
Rat (Rattus) , , , ,

Top referenced anti-Tumor Protein P53 Binding Protein 2 Antibodies

  1. Dog (Canine) Polyclonal TP53BP2 Primary Antibody for EIA, WB - ABIN401045 : Liu, Lu, Zhang, Zhong, Gu, Zhang, Yang, Xin: Downregulated mRNA expression of ASPP and the hypermethylation of the 5'-untranslated region in cancer cell lines retaining wild-type p53. in FEBS letters 2005 (PubMed)
    Show all 5 references for ABIN401045

  2. Human Monoclonal TP53BP2 Primary Antibody for IF, WB - ABIN968491 : Iwabuchi, Li, Massa, Trask, Date, Fields: Stimulation of p53-mediated transcriptional activation by the p53-binding proteins, 53BP1 and 53BP2. in The Journal of biological chemistry 1998 (PubMed)
    Show all 3 references for ABIN968491

  3. Human Polyclonal TP53BP2 Primary Antibody for EIA, WB - ABIN955298 : Hirata, Hinoda, Nakajima, Kikuno, Suehiro, Tabatabai, Ishii, Dahiya: The bcl2 -938CC genotype has poor prognosis and lower survival in renal cancer. in The Journal of urology 2009 (PubMed)
    Show all 3 references for ABIN955298

  4. Cow (Bovine) Polyclonal TP53BP2 Primary Antibody for WB - ABIN2780683 : Ju, Lee, Yang, Kim, Kang, Sohn, Rhee, Kang, Kim: TP53BP2 locus is associated with gastric cancer susceptibility. in International journal of cancer. Journal international du cancer 2005 (PubMed)

  5. Human Polyclonal TP53BP2 Primary Antibody for IHC, ELISA - ABIN1584022 : Matsumoto, Weckbecker, Cory: Antineoplastic effect of the combination of 2,3-dihydro-1H-pyrazole[2,3a]imidazole plus deoxyadenosine/erythro-9-(2-hydroxyl-3-nonyl)adenine in mice with L1210 leukemia cells. in Cancer communications 1990 (PubMed)

More Antibodies against Tumor Protein P53 Binding Protein 2 Interaction Partners

Zebrafish Tumor Protein P53 Binding Protein 2 (TP53BP2) interaction partners

  1. These findings uncover a novel role of Aspp2 in regulating vertebrate embryonic growth.

Mouse (Murine) Tumor Protein P53 Binding Protein 2 (TP53BP2) interaction partners

  1. After genotoxic stress, Aspp1 (show PPP1R13B Antibodies) promotes hematopoietic stem cell (HSC (show FUT1 Antibodies)) cycling and induces p53 (show TP53 Antibodies)-dependent apoptosis in cells with persistent DNA damage foci. Aspp1 (show PPP1R13B Antibodies) also attenuates HSC (show FUT1 Antibodies) self-renewal and accumulation of DNA damage in p53 (show TP53 Antibodies) null HSCs.

  2. ASPP2 may participate in the lipid metabolism of non-alcoholic steatohepatitis and attenuate liver failure.

  3. ASPP2 prevents beta-catenin (show CTNNB1 Antibodies) from transactivating ZEB1 (show ZEB1 Antibodies) directly by forming an ASPP2-beta-catenin (show CTNNB1 Antibodies)-E-cadherin (show CDH1 Antibodies) ternary complex

  4. findings suggest that the identified STAT1 (show STAT1 Antibodies)/ASPP2 pathway may connect tumor suppression and cell polarity to neuroinflammation

  5. our studies demonstrate the role of Siah2 (show SIAH2 Antibodies) in regulation of tight junction integrity and cell polarity under hypoxia, through its regulation of ASPP2 stability.

  6. ASPP2 is a tumor suppressor that suppresses squamous cell carcinoma via inflammatory signaling through NF-kappaB (show NFKB1 Antibodies)-mediated repression of p63 (show CKAP4 Antibodies).

  7. Our study demonstrates a novel role for ASPP1 (show PPP1R13B Antibodies) and ASPP2 in the death of retinal ganglion cells.

  8. regulates epithelial cell polarity in cooperation with PAR-3 (show F2RL2 Antibodies) to form an active PAR (show AFG3L2 Antibodies) complex

  9. Consistent with its role in cell polarity, ASPP2 influences interkinetic nuclear migration and lamination during CNS development.

  10. ASPP2 is a haploinsufficient tumor suppressor that shares overlapping function(s) with p53 (show TP53 Antibodies) in mouse development and tumor suppression.

Human Tumor Protein P53 Binding Protein 2 (TP53BP2) interaction partners

  1. ASSP2 expression is lower in cancerous tissues and decreased ASPP2 lead to higher cancer cells proliferation and autophagic flux, which contribute to the gemcitabine resistance.

  2. this study revealed a novel function of ASPP2 in modulating autophagy and apoptosis.

  3. ASPP2 may participate in the lipid metabolism of non-alcoholic steatohepatitis and attenuate liver failure.

  4. These results identify previously uncharacterized regions distributed throughout the protein sequence of ASPP2 as determinants of CagA (show S100A8 Antibodies) binding, providing mechanistic insight into apoptosis reprogramming by CagA (show S100A8 Antibodies).

  5. ASPP2 directly induces the dephosphorylation and activation of junctional YAP (show YAP1 Antibodies)

  6. CHOP (show DDIT3 Antibodies) is critical for mediating ASPP2-induced autophagic apoptosis by decreasing Bcl-2 (show BCL2 Antibodies) expression and maintaining nuclear ASPP2-Bcl-2 (show BCL2 Antibodies) complexes.

  7. ASPP1 (show PPP1R13B Antibodies)/2 interacted with centrosome linker protein (show LAT Antibodies) C (show PROC Antibodies)-Nap1 (show CEP250 Antibodies). Co-depletion of ASPP1 (show PPP1R13B Antibodies) and ASPP2 inhibited re-association of C-Nap1 (show CEP250 Antibodies) with centrosome at the end of mitosis.

  8. these observations reveal that Itch and Yap1 (show YAP1 Antibodies) have antagonistic roles in the regulation of ASPP2 protein stability through competing post-translational regulatory mechanism of ASPP2.

  9. ASPP2 prevents beta-catenin (show CTNNB1 Antibodies) from transactivating ZEB1 (show ZEB1 Antibodies) directly by forming an ASPP2-beta-catenin (show CTNNB1 Antibodies)-E-cadherin (show CDH1 Antibodies) ternary complex

  10. phosphorylation of ASPP2 by RAS/MAPK (show MAPK1 Antibodies) pathway provides a novel link between RAS and p53 (show TP53 Antibodies) in regulating apoptosis

Tumor Protein P53 Binding Protein 2 (TP53BP2) Antigen Profile

Protein Summary

This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with TP53BP2

  • tumor protein p53 binding protein, 2 (TP53BP2) antibody
  • tumor protein p53 binding protein, 2 (tp53bp2) antibody
  • si:dkeyp-34c12.2 (si:dkeyp-34c12.2) antibody
  • protein phosphatase 1, regulatory (inhibitor) subunit 13B (Ppp1r13b) antibody
  • transformation related protein 53 binding protein 2 (Trp53bp2) antibody
  • tumor protein p53 binding protein, 2 (Tp53bp2) antibody
  • 53BP2 antibody
  • AI449786 antibody
  • AI746547 antibody
  • ASPP1 antibody
  • ASPP2 antibody
  • AW545810 antibody
  • BBP antibody
  • P53BP2 antibody
  • p85 antibody
  • PPP1R13A antibody
  • Tp53bp2 antibody
  • Trp53bp2 antibody
  • wu:fa09h08 antibody
  • wu:fb04e08 antibody
  • X98550 antibody
  • zgc:85720 antibody

Protein level used designations for TP53BP2

tumor protein p53 binding protein, 2 , apoptosis-stimulating of p53 protein 2-like , apoptosis-stimulating of p53 protein 1 , protein phosphatase 1 regulatory subunit 13B , transformation related protein 53 binding protein 2 , tumor protein p53-binding protein, 2 , apoptosis-stimulating of p53 protein 2 , p53-binding protein 2 , p53BP2 , tumor suppressor p53-binding protein 2 , fb04e08 , BCL2-binding protein , apoptosis-stimulating protein of p53, 2 , renal carcinoma antigen NY-REN-51

GENE ID SPECIES
421329 Gallus gallus
457766 Pan troglodytes
548790 Xenopus (Silurana) tropicalis
568138 Danio rerio
705383 Macaca mulatta
100055278 Equus caballus
100221962 Taeniopygia guttata
100445132 Pongo abelii
100519863 Sus scrofa
21981 Mus musculus
209456 Mus musculus
407983 Danio rerio
446947 Xenopus laevis
7159 Homo sapiens
490397 Canis lupus familiaris
514474 Bos taurus
305025 Rattus norvegicus
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