anti-Tumor Protein P63 (TP63) Antibodies

TP63 encodes a member of the p53 family of transcription factors. Additionally we are shipping p63 Kits (30) and p63 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TP63 8626 Q9H3D4
TP63 246334 Q9JJP6
TP63 21454 P11983
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Top anti-p63 Antibodies at antibodies-online.com

Showing 10 out of 79 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB TP63 Antibody (C-term) (ABIN657886) western blot analysis in MDA-MB231 cell line lysates (35 µg/lane). This demonstrates the TP63 antibody detected the TP63 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ICC, IHC (p), WB Anti-p63 Picoband antibody,  IHC(P): Human Oesophagus Squama Cancer Tissue Anti-p63 Picoband antibody,  All lanes: Anti P63  at 0.5ug/ml WB: Recombinant Human P63 Protein 0.5ng Predicted bind size: 39KD Observed bind size: 39KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated ICC, IHC (p), WB Anti-p63 antibody, IHC(P) IHC(P): Human Lung Cancer Tissue Anti-p63 antibody, Western blotting Lane 1: HELA Cell Lysate Lane 2: SMMC Cell Lysate Lane 3: COLO320 Cell Lysate Lane 4: A549 Cell Lysate Lane 5: SGC Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Mouse Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$481.25
Details
Human Mouse Un-conjugated IHC (p) Detection of p63 protein in nucleus of epidermis stained with anti-p63 antibody 10 mL Log in to see 5 to 6 Days
$474.38
Details
Human Mouse Un-conjugated WB TP63 Antibody (Ascites) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the TP63 antibody detected the TP63 protein (arrow). 0.1 mL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemistry of paraffin-embedded rat kidney using TP63 antibody at dilution of 1:100 (x400 lens). 100 μL Log in to see 16 Days
$334.02
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged TP73L is approximately 0.3 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated ELISA, WB   50 μg Log in to see 2 to 3 Days
$192.50
Details

TP63 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-p63 Antibodies

  1. Human Polyclonal p63 Primary Antibody for WB - ABIN657886 : Miki, Kubo, Takahashi, Yoon, Kim, Lee, Zo, Lee, Hosono, Morizono, Tsunoda, Kamatani, Chayama, Takahashi, Inazawa, Nakamura, Daigo: Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations. in Nature genetics 2010 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal p63 Primary Antibody for IHC, WB - ABIN2673817 : Zhang, Wei, Dang, Xie, Zhong, Ma, Chen: Primary urinary bladder adenosquamous carcinoma complicated with lower limb deep venous thromboses: a case report. in International journal of clinical and experimental pathology 2015 (PubMed)

More Antibodies against p63 Interaction Partners

Human Tumor Protein P63 (TP63) interaction partners

  1. Dysregulation of JAM-A (show F11R Antibodies) via p63 (show RPE65 Antibodies)/GATA-3 (show GATA3 Antibodies) signaling pathway occurs in squamous cell carcinomas of the head and neck.

  2. This study investigated the expression of p40 (show IL9 Antibodies) protein in meningiomas and explored its usefulness as prognostic marker in addition to PgR (show PGR Antibodies) and Ki67 (show MKI67 Antibodies).

  3. the transactivation inhibitory (TI) domains within the alpha-isoform-specific C termini of p63 (show RPE65 Antibodies) and p73 (show TP73 Antibodies) are essential for binding to p53R175H.

  4. Data show that a two-marker panel of p40 (show IL9 Antibodies) (DeltaNp63) and CDX2 (show CDX2 Antibodies) is highly sensitive and specific.

  5. DeltaNp63alpha (TP63) is co-expressed with FAT2 and Slug in patient tumors and the elevated expression of DeltaNp63alpha, FAT2 and Slug correlated with poor patient outcome.

  6. Keratin14/p63 (show RPE65 Antibodies)-positive epithelial proliferations suggest benign breast disease.

  7. Yes associated protein 1 (YAP (show YAP1 Antibodies)) activation led to excessive accumulation of reactive oxygen species (ROS (show ROS1 Antibodies)) by downregulating the antioxidant enzyme glutathione peroxidase GPX2 (show GPX1 Antibodies) in a manner related to tumor protein p63 blockade.

  8. We identified a previously unreported variant in TP63 gene which seems to be involved in the somatic malformations found in the AEC syndrome. The absence of this variant in both parents suggests that the variant appeared de novo.

  9. Allele-specific silencing of ectrodactily-ectodermal dysplasia and cleft lip/palate syndrome p63 (show RPE65 Antibodies) mutant R304W restores p63 (show RPE65 Antibodies) transcriptional activity.

  10. Data suggest that this the selective targeting of genes by tumor suppressor protein (show TP53 Antibodies) p63 (p63 (show RPE65 Antibodies)) correlates with subtle, but measurable transcriptional differences in mouse and human keratinocytes that converges on major metabolic processes, which often exhibit species-specific trends.

Horse (Equine) Tumor Protein P63 (TP63) interaction partners

  1. p63 expression was significantly lower in the chronic laminitic hoof than in that of control horses

Zebrafish Tumor Protein P63 (TP63) interaction partners

  1. they unravel essential roles of TAp63 and p53 (show TP53 Antibodies) to promote both keratinocyte proliferation and their terminal differentiation by promoting Notch (show NOTCH1 Antibodies) signalling and caspase 3 (show CASP3 Antibodies) activity.

  2. the p63 transcription factor is upregulated to initiate this apoptotic pathway and directly activates puma (show BBC3 Antibodies) transcription in response to ER stress.

  3. Early zebrafish embryos express a dominant-negative form of p63 (DeltaNp63), which accumulates in the nucleus just as epidermal growth begins. (p63)

  4. DeltaNp63 expression blocks neural development and promotes nonneural development, even in the absence of Bmp signaling. (DeltaNp63)

  5. rps19 (show RPS19 Antibodies)-deficient phenotype is mediated by dysregulation of deltaNp63 and p53 (show TP53 Antibodies) and results in hematopoietic and developmental abnormalities resembling Diamond-Blackfan anemia

Mouse (Murine) Tumor Protein P63 (TP63) interaction partners

  1. cells expressing both p63 (show CKAP4 Antibodies) and p73 (show ARHGAP24 Antibodies) exist in mouse epidermis and hair follicle and that hetero-tetramer complexes can be detected by immunoprecipitation in differentiating keratinocytes.

  2. Data suggest that this the selective targeting of genes by tumor suppressor protein (show TP53 Antibodies) p63 (p63 (show CKAP4 Antibodies)) correlates with subtle, but measurable transcriptional differences in mouse and human keratinocytes that converges on major metabolic processes, which often exhibit species-specific trends.

  3. p63alpha protein up-regulates heat shock protein 70 (show HSP70 Antibodies) expression via E2F1 transcription factor (show E2F1 Antibodies) 1 (show HNF1A Antibodies), promoting Wasf3/Wave3 (show WASF3 Antibodies)/MMP9 (show MMP9 Antibodies) signaling and bladder cancer invasion

  4. these results therefore highlight an unanticipated role for p53 (show TP53 Antibodies) family proteins in a regulatory network that integrates essential Wnt (show WNT2 Antibodies)-Tcf (show HNF4A Antibodies) and nodal-Smad (show SMAD1 Antibodies) inputs.

  5. the double mutant spermatocytes apoptosed at late pachynema because of sex body deficiency; thus p53 (show TP53 Antibodies) and TAp63 are dispensable for arrest caused by sex body defects. These data affirm that recombination-dependent and sex body-deficient arrests occur via genetically separable mechanisms.

  6. TGFb3 (show TGFB3 Antibodies)-induced down-regulation of p63 (show CKAP4 Antibodies) in the medial edge epithelia of the palatal shelves is a pre-requisite for palatal fusion by facilitating periderm migration from, and reducing the proliferative potential of, the midline epithelial seam thereby preventing cleft palate.

  7. miR (show MLXIP Antibodies)-20a-5p contributes to hepatic glycogen (show GYS1 Antibodies) synthesis through targeting p63 (show CKAP4 Antibodies) to regulate p53 (show TP53 Antibodies) and PTEN (show PTEN Antibodies) expression.

  8. this study shows that CCTalpha (show PCYT1A Antibodies) is required for antigen-specific, germinal center-derived memory B cells

  9. Taken together, these data show that p63 (show CKAP4 Antibodies) regulates the self-renewal and differentiation of oesophageal stem cells in humans and mice.

  10. IL-6 (show IL6 Antibodies)/P-STAT3 (show STAT3 Antibodies) activation influences p63 (show CKAP4 Antibodies) isoform expression in healing wounds, which may contribute to wound-induced hair follicle neogenesis.

Xenopus laevis Tumor Protein P63 (TP63) interaction partners

  1. Data indicate that pluripotency genes sox2, p63 and oct60 are upregulated early during the process of lens regeneration.

  2. The results suggest that DeltaNp63 is an essential gene in early epidermal specification under the control of BMP4 (show BMP4 Antibodies).

  3. The role of p63 as a negative Wnt (show WNT2 Antibodies)-regulator thus matches with the frequently observed downregulation of p63 during tumor progression, when cancer cells adopt a more mesenchymal, invasive phenotype.

p63 (TP63) Antigen Profile

Protein Summary

This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3)\; split-hand/foot malformation 4 (SHFM4)\; ankyloblepharon-ectodermal defects-cleft lip/palate\; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth)\; limb-mammary syndrome\; Rap-Hodgkin syndrome (RHS)\; and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined.

Gene names and symbols associated with TP63

  • tumor protein p63 (TP63) antibody
  • tumor protein p63 (tp63) antibody
  • tumor protein p63 (Tp63) antibody
  • tumor protein p73 (TP73) antibody
  • tumor protein p73 (tp73) antibody
  • cellular tumor antigen p53 (LOC100577122) antibody
  • tumor protein p73 (LOC100594205) antibody
  • cellular tumor antigen p53 (LOC100648488) antibody
  • t-complex protein 1 (Tcp1) antibody
  • transformation related protein 63 (Trp63) antibody
  • tumor protein p63 L homeolog (tp63.L) antibody
  • AI462811 antibody
  • AI528772 antibody
  • AIS antibody
  • B(p51A) antibody
  • B(p51B) antibody
  • c-cpn antibody
  • CCT antibody
  • Cct1 antibody
  • Ccta antibody
  • DNp63 antibody
  • EEC3 antibody
  • id:ibd3516 antibody
  • ket antibody
  • LMS antibody
  • NBP antibody
  • np63 antibody
  • OFC8 antibody
  • p40 antibody
  • p51 antibody
  • P51/P63 antibody
  • p53CP antibody
  • P63 antibody
  • p73H antibody
  • P73l antibody
  • RHS antibody
  • SHFM4 antibody
  • Tcp-1 antibody
  • TP53CP antibody
  • TP53L antibody
  • Tp63 antibody
  • Tp73l antibody
  • tp73l-A antibody
  • TRic antibody
  • Trp53rp1 antibody
  • trp63 antibody
  • wu:fc89f04 antibody
  • wu:fk85h07 antibody
  • wu:fk88b02 antibody
  • Xp63 antibody

Protein level used designations for TP63

CUSP , amplified in squamous cell carcinoma , chronic ulcerative stomatitis protein , keratinocyte transcription factor KET , transformation-related protein 63 , tumor protein 63 , tumor protein p53-competing protein , tumor protein p63 deltaN isoform delta , tumor protein p63 , delta-Np63 , fc89f04 , transformation related protein 63 , tumor protein 63 kDa , tumor protein 63-like , tumor protein p73-like , CCT-alpha , T-complex protein 1 subunit alpha , T-complex protein 1 subunit alpha A , T-complex protein 1 subunit alpha B , TCP-1-A , TCP-1-B , TCP-1-alpha , t-complex polypeptide 1 , tailless complex polypeptide 1A , tailless complex polypeptide 1B

GENE ID SPECIES
8626 Homo sapiens
100059752 Equus caballus
100170632 Oryzias latipes
260407 Danio rerio
703997 Macaca mulatta
615335 Bos taurus
246334 Rattus norvegicus
374269 Gallus gallus
460930 Pan troglodytes
488125 Canis lupus familiaris
100227936 Taeniopygia guttata
100386953 Callithrix jacchus
100393670 Callithrix jacchus
100433100 Pongo abelii
100444448 Pongo abelii
100480840 Ailuropoda melanoleuca
100496308 Xenopus (Silurana) tropicalis
100545037 Meleagris gallopavo
100577122 Apis mellifera
100594205 Nomascus leucogenys
100606847 Nomascus leucogenys
100611345 Pan troglodytes
100648488 Bombus terrestris
21454 Mus musculus
22061 Mus musculus
373640 Xenopus laevis
100625258 Sus scrofa
100355881 Oryctolagus cuniculus
100732143 Cavia porcellus
101108874 Ovis aries
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