anti-Tumor Protein P63 (TP63) Antibodies

TP63 encodes a member of the p53 family of transcription factors. Additionally we are shipping p63 Kits (28) and p63 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TP63 21454 P11983
TP63 8626 Q9H3D4
TP63 246334 Q9JJP6
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Top anti-p63 Antibodies at antibodies-online.com

Showing 10 out of 79 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB TP63 Antibody (C-term) (ABIN657886) western blot analysis in MDA-MB231 cell line lysates (35 µg/lane). This demonstrates the TP63 antibody detected the TP63 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ICC, IHC (p), WB Anti-p63 Picoband antibody,  IHC(P): Human Oesophagus Squama Cancer Tissue Anti-p63 Picoband antibody,  All lanes: Anti P63  at 0.5ug/ml WB: Recombinant Human P63 Protein 0.5ng Predicted bind size: 39KD Observed bind size: 39KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated ICC, IHC (p), WB Anti-p63 antibody, IHC(P) IHC(P): Human Lung Cancer Tissue Anti-p63 antibody, Western blotting Lane 1: HELA Cell Lysate Lane 2: SMMC Cell Lysate Lane 3: COLO320 Cell Lysate Lane 4: A549 Cell Lysate Lane 5: SGC Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Mouse Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$481.25
Details
Human Mouse Un-conjugated IHC (p) Detection of p63 protein in nucleus of epidermis stained with anti-p63 antibody 10 mL Log in to see 5 to 6 Days
$433.13
Details
Human Mouse Un-conjugated WB TP63 Antibody (Ascites) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the TP63 antibody detected the TP63 protein (arrow). 0.1 mL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemistry of paraffin-embedded rat kidney using TP63 antibody at dilution of 1:100 (x400 lens). 100 μL Log in to see 16 Days
$323.13
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged TP73L is approximately 0.3 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated IHC (p)   5 mL Log in to see 5 to 6 Days
$216.56
Details

TP63 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,
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Top referenced anti-p63 Antibodies

  1. Human Polyclonal p63 Primary Antibody for WB - ABIN657886 : Miki, Kubo, Takahashi, Yoon, Kim, Lee, Zo, Lee, Hosono, Morizono, Tsunoda, Kamatani, Chayama, Takahashi, Inazawa, Nakamura, Daigo: Variation in TP63 is associated with lung adenocarcinoma susceptibility in Japanese and Korean populations. in Nature genetics 2010 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal p63 Primary Antibody for IHC, WB - ABIN2673817 : Zhang, Wei, Dang, Xie, Zhong, Ma, Chen: Primary urinary bladder adenosquamous carcinoma complicated with lower limb deep venous thromboses: a case report. in International journal of clinical and experimental pathology 2015 (PubMed)

More Antibodies against p63 Interaction Partners

Horse (Equine) Tumor Protein P63 (TP63) interaction partners

  1. p63 expression was significantly lower in the chronic laminitic hoof than in that of control horses

Mouse (Murine) Tumor Protein P63 (TP63) interaction partners

  1. Data suggest that this the selective targeting of genes by tumor suppressor protein (show TP53 Antibodies) p63 (p63 (show CKAP4 Antibodies)) correlates with subtle, but measurable transcriptional differences in mouse and human keratinocytes that converges on major metabolic processes, which often exhibit species-specific trends.

  2. p63alpha protein up-regulates heat shock protein 70 (show HSP70 Antibodies) expression via E2F1 transcription factor (show E2F1 Antibodies) 1 (show HNF1A Antibodies), promoting Wasf3/Wave3 (show WASF3 Antibodies)/MMP9 (show MMP9 Antibodies) signaling and bladder cancer invasion

  3. these results therefore highlight an unanticipated role for p53 (show TP53 Antibodies) family proteins in a regulatory network that integrates essential Wnt (show WNT2 Antibodies)-Tcf (show HNF4A Antibodies) and nodal-Smad (show SMAD1 Antibodies) inputs.

  4. the double mutant spermatocytes apoptosed at late pachynema because of sex body deficiency; thus p53 (show TP53 Antibodies) and TAp63 are dispensable for arrest caused by sex body defects. These data affirm that recombination-dependent and sex body-deficient arrests occur via genetically separable mechanisms.

  5. TGFb3 (show TGFB3 Antibodies)-induced down-regulation of p63 (show CKAP4 Antibodies) in the medial edge epithelia of the palatal shelves is a pre-requisite for palatal fusion by facilitating periderm migration from, and reducing the proliferative potential of, the midline epithelial seam thereby preventing cleft palate.

  6. miR (show MLXIP Antibodies)-20a-5p contributes to hepatic glycogen (show GYS1 Antibodies) synthesis through targeting p63 (show CKAP4 Antibodies) to regulate p53 (show TP53 Antibodies) and PTEN (show PTEN Antibodies) expression.

  7. this study shows that CCTalpha (show PCYT1A Antibodies) is required for antigen-specific, germinal center-derived memory B cells

  8. Taken together, these data show that p63 (show CKAP4 Antibodies) regulates the self-renewal and differentiation of oesophageal stem cells in humans and mice.

  9. IL-6 (show IL6 Antibodies)/P-STAT3 (show STAT3 Antibodies) activation influences p63 (show CKAP4 Antibodies) isoform expression in healing wounds, which may contribute to wound-induced hair follicle neogenesis.

  10. In vivo inhibition of both p63 (show CKAP4 Antibodies) and p73 (show ARHGAP24 Antibodies) in combination accelerates tumor regression and increases survival of p53 (show TP53 Antibodies)-deficient mice.

Human Tumor Protein P63 (TP63) interaction partners

  1. Allele-specific silencing of ectrodactily-ectodermal dysplasia and cleft lip/palate syndrome p63 (show RPE65 Antibodies) mutant R304W restores p63 (show RPE65 Antibodies) transcriptional activity.

  2. Data suggest that this the selective targeting of genes by tumor suppressor protein (show TP53 Antibodies) p63 (p63 (show RPE65 Antibodies)) correlates with subtle, but measurable transcriptional differences in mouse and human keratinocytes that converges on major metabolic processes, which often exhibit species-specific trends.

  3. This report illustrates the potential severity of urogenital defects in TP63-related disorders, which may be detectable with fetal ultrasonography. It highlights the need to counsel for the possibility of germline mosaicism in TP63-associated disorders.

  4. p63alpha protein up-regulates heat shock protein 70 (show HSP70 Antibodies) expression via E2F1 transcription factor (show E2F1 Antibodies) 1 (show HNF1A Antibodies), promoting Wasf3/Wave3 (show WASF3 Antibodies)/MMP9 (show MMP9 Antibodies) signaling and bladder cancer invasion

  5. High TP63 expression is associated with growth, metastasis and stemness of oral squamous cell carcinoma.

  6. present observations strongly suggest that RUNX2 (show RUNX2 Antibodies)/mutant p53 (show TP53 Antibodies)/TAp63-regulatory axis is one of the key determinants of SAHA sensitivity of p53 (show TP53 Antibodies)-mutated pancreatic cancer cells

  7. a major effect of p63 (show RPE65 Antibodies) is regulation of cell adhesion, a process important in metastasis and invasion of tumour cells. That this effect is not seen in mesenchymal-type TNBC cells suggests lineage-dependent functions, mirroring the expression of Np63alpha in primary human breast cancers.

  8. p63 (show RPE65 Antibodies) is a master regulator in epidermal biology and regulates glycolysis sugar taste in the epidermis.

  9. Anaplastic large cell lymphomas without TP63 rearrangements may express TAp63 isoforms of p63 (show RPE65 Antibodies) and this expression is associated with extra copies of TP63, probably due to widespread genomic copy number abnormalities rather than focal gains.

  10. Up-regulation of transcription factor DeltaNp63 led to the decline of miR (show MLXIP Antibodies)-181a expression, resulting in an overexpression of the antiaging protein Sirt1 (show SIRT1 Antibodies), in CD4 (show CD4 Antibodies)(+) T cells from HCV-infected individuals. Either reconstituting miR (show MLXIP Antibodies)-181a or silencing DeltaNp63 or Sirt1 (show SIRT1 Antibodies) expression in CD4 (show CD4 Antibodies)(+) T cells led to accelerated T cell senescence.

Zebrafish Tumor Protein P63 (TP63) interaction partners

  1. they unravel essential roles of TAp63 and p53 (show TP53 Antibodies) to promote both keratinocyte proliferation and their terminal differentiation by promoting Notch (show NOTCH1 Antibodies) signalling and caspase 3 (show CASP3 Antibodies) activity.

  2. the p63 transcription factor is upregulated to initiate this apoptotic pathway and directly activates puma (show BBC3 Antibodies) transcription in response to ER stress.

  3. Early zebrafish embryos express a dominant-negative form of p63 (DeltaNp63), which accumulates in the nucleus just as epidermal growth begins. (p63)

  4. DeltaNp63 expression blocks neural development and promotes nonneural development, even in the absence of Bmp signaling. (DeltaNp63)

  5. rps19 (show RPS19 Antibodies)-deficient phenotype is mediated by dysregulation of deltaNp63 and p53 (show TP53 Antibodies) and results in hematopoietic and developmental abnormalities resembling Diamond-Blackfan anemia

Xenopus laevis Tumor Protein P63 (TP63) interaction partners

  1. Data indicate that pluripotency genes sox2, p63 and oct60 are upregulated early during the process of lens regeneration.

  2. The results suggest that DeltaNp63 is an essential gene in early epidermal specification under the control of BMP4 (show BMP4 Antibodies).

  3. The role of p63 as a negative Wnt (show WNT2 Antibodies)-regulator thus matches with the frequently observed downregulation of p63 during tumor progression, when cancer cells adopt a more mesenchymal, invasive phenotype.

p63 (TP63) Antigen Profile

Protein Summary

This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3)\; split-hand/foot malformation 4 (SHFM4)\; ankyloblepharon-ectodermal defects-cleft lip/palate\; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth)\; limb-mammary syndrome\; Rap-Hodgkin syndrome (RHS)\; and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined.

Gene names and symbols associated with TP63

  • tumor protein p63 (TP63) antibody
  • tumor protein p63 (tp63) antibody
  • tumor protein p63 (LOC100227936) antibody
  • tumor protein p73-like (LOC100393670) antibody
  • tumor protein p73-like (LOC100433100) antibody
  • tumor protein p73-like (LOC100480840) antibody
  • tumor protein p73-like (LOC100496308) antibody
  • tumor protein p73-like (LOC100512967) antibody
  • tumor protein p73-like (LOC100545037) antibody
  • tumor protein p73-like (LOC100577122) antibody
  • tumor protein p73-like (LOC100594205) antibody
  • tumor protein p73-like (LOC100611345) antibody
  • tumor protein p73-like (LOC100624851) antibody
  • tumor protein p73-like (LOC100648488) antibody
  • t-complex protein 1 (Tcp1) antibody
  • transformation related protein 63 (Trp63) antibody
  • tumor protein p63 (Tp63) antibody
  • tumor protein p63-like (LOC100355881) antibody
  • AI462811 antibody
  • AI528772 antibody
  • AIS antibody
  • B(p51A) antibody
  • B(p51B) antibody
  • c-cpn antibody
  • CCT antibody
  • Cct1 antibody
  • Ccta antibody
  • DNp63 antibody
  • EEC3 antibody
  • id:ibd3516 antibody
  • ket antibody
  • LMS antibody
  • NBP antibody
  • np63 antibody
  • OFC8 antibody
  • p40 antibody
  • p51 antibody
  • P51/P63 antibody
  • p53CP antibody
  • P63 antibody
  • p73H antibody
  • p73L antibody
  • RHS antibody
  • SHFM4 antibody
  • Tcp-1 antibody
  • TP53CP antibody
  • TP53L antibody
  • Tp63 antibody
  • tp73l antibody
  • tp73l-A antibody
  • TRic antibody
  • Trp53rp1 antibody
  • TRP63 antibody
  • wu:fc89f04 antibody
  • wu:fk85h07 antibody
  • wu:fk88b02 antibody
  • Xp63 antibody

Protein level used designations for TP63

tumor protein p63 , tumor protein 63 , p63 gamma , tumor protein p73-like , tumor protein 63-like , CCT-alpha , T-complex protein 1 subunit alpha , T-complex protein 1 subunit alpha A , T-complex protein 1 subunit alpha B , TCP-1-A , TCP-1-B , TCP-1-alpha , t-complex polypeptide 1 , tailless complex polypeptide 1A , tailless complex polypeptide 1B , transformation-related protein 63 , CUSP , amplified in squamous cell carcinoma , chronic ulcerative stomatitis protein , keratinocyte transcription factor KET , tumor protein p53-competing protein , tumor protein p63 deltaN isoform delta , transformation related protein 63 , tumor protein 63 kDa , delta-Np63 , fc89f04

GENE ID SPECIES
100059752 Equus caballus
100170632 Oryzias latipes
703997 Macaca mulatta
100048992 Ovis aries
460930 Pan troglodytes
100227936 Taeniopygia guttata
100386953 Callithrix jacchus
100393670 Callithrix jacchus
100433100 Pongo abelii
100444448 Pongo abelii
100480840 Ailuropoda melanoleuca
100496308 Xenopus (Silurana) tropicalis
100512967 Sus scrofa
100545037 Meleagris gallopavo
100577122 Apis mellifera
100594205 Nomascus leucogenys
100606847 Nomascus leucogenys
100611345 Pan troglodytes
100624851 Sus scrofa
100648488 Bombus terrestris
21454 Mus musculus
22061 Mus musculus
8626 Homo sapiens
246334 Rattus norvegicus
260407 Danio rerio
373640 Xenopus laevis
374269 Gallus gallus
100732143 Cavia porcellus
100625258 Sus scrofa
488125 Canis lupus familiaris
615335 Bos taurus
101108874 Ovis aries
100355881 Oryctolagus cuniculus
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