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TUSC2 is a highly conserved lung cancer candidate gene. Additionally we are shipping Tumor Suppressor Candidate 2 Antibodies (47) and Tumor Suppressor Candidate 2 Proteins (3) and many more products for this protein.
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FOXP1 (show FOXP1 ELISA Kits), TP53INP1 (show TP53INP1 ELISA Kits), TNFAIP3 (show TNFAIP3 ELISA Kits), and TUSC2 were identified as miR (show MLXIP ELISA Kits)-19a targets.
The therapeutic activity of TUSC2 could extend the use of erlotinib to lung cancer patients with wildtype EGFR (show EGFR ELISA Kits).
TUSC2P and TUSC2 3'-UTR (show UTS2R ELISA Kits) expression inhibits cell proliferation, survival, migration, invasion and colony formation, and increases tumor cell death. TUSC2P and TUSC2 3'-UTR (show UTS2R ELISA Kits) bind to miRNAs and arrest their functions, leading to increased TUSC2 translation.
The tumor suppressor gene TUSC2 (FUS1) sensitizes NSCLC to the AKT (show AKT1 ELISA Kits) inhibitor MK2206 in LKB1 (show STK11 ELISA Kits)-dependent manner.
RNA sequence elements in FUS1 (show FUS ELISA Kits) UTRs that regulate FUS1 (show FUS ELISA Kits) protein express were identified.
Absence of tumor suppressor FUS1 (show FUS ELISA Kits) protein expression is associated with bone and soft tissue sarcomas.
Data show that the recombinant FUS1 (show FUS ELISA Kits) plasmid has been successfully cloned, which allows highly efficient FUS1 (show FUS ELISA Kits) expression in E.coli strain Rosetta (DE3)2 plys.
The goal of this study was to analyze possible involvement of TUSC2 in malignant pleural mesothelioma.
Myristoylation is required for Fus1 (show FUS ELISA Kits)-mediated tumor-suppressing activity and suggest a novel mechanism for the inactivation of tumor suppressors in lung cancer.
These results suggest that miR (show MLXIP ELISA Kits)-378 enhances cell survival, tumor growth, and angiogenesis through repression of the expression of two tumor suppressors, Sufu (show SUFUH ELISA Kits) and Fus-1 (show FUS ELISA Kits).
Fus1 achieves its protective role in inflammation, autoimmunity, and cancer via the regulation of mitochondrial calcium and calcium-coupled parameters.
This gene is a highly conserved lung cancer candidate gene. No other information about this gene is currently available.
tumor suppressor candidate 2
, PDGFA associated protein 2
, PDGFA-associated protein 2
, fus-1 protein
, fusion 1 protein
, lung cancer candidiate, FUS