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anti-Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) Antibodies

This intronless gene encodes a carcinoma-associated antigen. Additionally we are shipping TACSTD2 Proteins (16) and TACSTD2 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TACSTD2 22004 P58774
TACSTD2 4070 P09758
TACSTD2 494343 Q6P9Z6
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Top anti-TACSTD2 Antibodies at antibodies-online.com

Showing 10 out of 121 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of TROP2 antibody (Center) in HL60 cell line lysates (35ug/lane). TROP2 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated ELISA, WB ABIN308423 (0.2 ug/ml) staining of Human Prostate lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of TROP2 antibody (Center) (ABIN390632) in HL60 cell line lysates (35 µg/lane). TROP2 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human prostate carcinoma with TROP2 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from A549/NIH-3T3 cells, using TACD2 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Mouse Rabbit Un-conjugated WB Mouse Crkl Antibody (C-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the Crkl antibody detected the Crkl protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated FACS, IHC (p), ELISA Immunochemical staining of human TROP2 in human placenta with mouse monoclonal antibody (15 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to membrane of cytotrophoblast. Immunochemical staining of human TROP2 in human mammary gland with mouse monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to membrane of alveolus epithelium. 100 μg Log in to see 16 Days
$218.90
Details
Human Goat Un-conjugated IHC (p), ELISA, WB Anti-TROP2 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN962687 concentration 41396 ug/ml. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of TACSTD2 staining in A549 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a hidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of TACSTD2 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 9 Days
$487.50
Details
Human Mouse FITC FACS, IF Immunofluorescence staining of Human TROP2 in MCF7 cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with Mouse anti-Human TROP2 monoclonal antibody (FITC-conjugated, 10 µg/ml) at 37℃ 1 hour. Positive staining was localized to pla 50 Tests Log in to see 16 Days
$198.00
Details

TACSTD2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-TACSTD2 Antibodies

  1. Human Polyclonal TACSTD2 Primary Antibody for EIA, WB - ABIN453439 : Goldstein, Lawson, Cheng, Sun, Garraway, Witte: Trop2 identifies a subpopulation of murine and human prostate basal cells with stem cell characteristics. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

  2. Human Polyclonal TACSTD2 Primary Antibody for WB - ABIN375030 : Shimada, Kano, Ishiyama, Okubo, Iijima, Morishita, Minami, Inadome, Shu, Sugita, Takeuchi, Noguchi: Establishment of an immortalized cell line from a precancerous lesion of lung adenocarcinoma, and genes highly expressed in the early stages of lung adenocarcinoma development. in Cancer science 2005 (PubMed)

More Antibodies against TACSTD2 Interaction Partners

Mouse (Murine) Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) interaction partners

  1. Trop-2 promotes an alpha5beta1 integrin-dependent pro-metastatic signaling pathway in PCa (show ENPP1 Antibodies) cells and that the altered expression of Trop-2 may be utilized for early identification of capsule-invading PCa (show ENPP1 Antibodies).

  2. studies have begun to identify the mechanisms underlying TROP2's functions, including regulated intramembrane proteolysis or specific interactions with integrin b1 and claudin proteins.

  3. our findings help to establish a close functional link between Trop2 and MSCs, and to provide a tool for future investigation of Trop2 in other types of stem cells

  4. data suggest that Trop2 regulates cell proliferation and motility and that it does so by regulating the ERK (show EPHB2 Antibodies) pathway and several critical components of the cell migration apparatus

  5. Trop2 plays a cardioprotective role by promoting cardiac c-kit (show KIT Antibodies)+ cell proliferation and inhibition of apoptosis in the acute phase of myocardial infarction.

  6. Trop2 is a regulator of self-renewal, proliferation, and transformation

  7. TROP2 modulates the interaction between the cells and matrix and regulates the formation of the ureteric duct by suppressing branching from the trunk during kidney development.

  8. these results uncover a role for Trop2 loss in tumorigenesis and the mesenchymal transdifferentiation observed in a subset of squamous cell carcinomas.

  9. In human and mouse, Trop2 is highly expressed at both the transcript and protein levels on several essential normal tissues.

  10. Study also provides the first indication of a molecular signaling pathway activated by Trop2 which has important implications for cancer cell growth and survival.

Human Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) interaction partners

  1. Trop-2 is a novel target for ADC (show ADC Antibodies) therapy because of its high expression by many solid cancers.

  2. TROP2 is epigenetically down-regulated and operates as a negative regulator of cell proliferation and migration in liver fluke-associated cholangiocarcinoma.

  3. TROP-2 is specifically expressed in papillary thyroid carcinoma.

  4. overexpression of TROP2 appears to be an independent predictor for poor clinical outcome in nasopharyngeal carcinoma

  5. Lower GA733-2 (show EPCAM Antibodies) expression in cancer tissues appeared to correlate with lymph node metastases (P < 0.05). GA733-1 gene expression was significantly higher in cancerous samples

  6. TROP-2 can be used as well as HBME-1 in thyroid cytology to detect PTC (show F9 Antibodies).

  7. Altogether, our data suggest that TROP2 plays an important role in promoting ADC (show ADC Antibodies) and may represent a novel prognostic biomarker and therapeutic target for the disease.

  8. TROP2 protein is expressed at high levels in the colon cancer tissues.

  9. TACSTD2 protein, human is predicting lymph node metastases in OSCC, overall survival and disease-free survival.

  10. The amino acid exchange resulting from 4461T[C does not appear to alter binding of HO-3 (show HARS2 Antibodies), suggesting that treatment with catumaxomab can be offered to patients regardless of their TACSTD1 (show EPCAM Antibodies)-genotype.

TACSTD2 Antigen Profile

Protein Summary

This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.

Gene names and symbols associated with TACSTD2

  • tropomyosin 2, beta (Tpm2) antibody
  • tumor-associated calcium signal transducer 2 (TACSTD2) antibody
  • tumor-associated calcium signal transducer 2 (Tacstd2) antibody
  • C80403 antibody
  • EGP-1 antibody
  • EGP1 antibody
  • GA733-1 antibody
  • GA7331 antibody
  • GP50 antibody
  • Ly97 antibody
  • M1S1 antibody
  • Prp1 antibody
  • Tpm-2 antibody
  • Trop-2 antibody
  • TROP2 antibody

Protein level used designations for TACSTD2

tropomyosin beta chain , 40kD glycoprotein, identified by monoclonal antibody GA733 , cell surface glycoprotein TROP2 , cell surface glycoprotein Trop-2 , epithelial glycoprotein-1 , gastrointestinal tumor-associated antigen GA7331 , membrane component chromosome 1 surface marker 1 , membrane component, chromosome 1, surface marker 1 , pancreatic carcinoma marker protein GA733-1 , pancreatic carcinoma marker protein GA7331 , lymphocyte antigen 97 , tunor-associated calcium signal transducer 2 , parturition-related protein 1

GENE ID SPECIES
22004 Mus musculus
4070 Homo sapiens
56753 Mus musculus
494343 Rattus norvegicus
Selected quality suppliers for anti-TACSTD2 (TACSTD2) Antibodies
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