anti-Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) Antibodies

This intronless gene encodes a carcinoma-associated antigen. Additionally we are shipping TACSTD2 Proteins (19) and TACSTD2 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TACSTD2 22004 P58774
TACSTD2 4070 P09758
TACSTD2 494343 Q6P9Z6
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Top anti-TACSTD2 Antibodies at antibodies-online.com

Showing 10 out of 171 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of TROP2 antibody (Center) in HL60 cell line lysates (35ug/lane). TROP2 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated ELISA, WB ABIN308423 (0.2 ug/ml) staining of Human Prostate lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$326.89
Details
Human Mouse Allophycocyanin FACS Detection of TROP-2 in PC-3 Human Cell Line by Flow Cytometry. PC-3 human prostate cancer cell line was stained with Mouse Anti-Human TROP-2 APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$372.75
Details
Mouse Goat Fluorescein FACS Detection of TROP-2 in XB2 Mouse Cell Line by Flow Cytometry. XB2 mouse teratoma keratinocyte cell line was stained with Goat Anti-Mouse TROP-2 Fluorescein-conjugated Antigen Affinity-purified Polyclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$267.75
Details
Human Mouse Un-conjugated FACS, WB Detection of TROP-2 in PC-3 Human Cell Line by Flow Cytometry. PC-3 human prostate cancer cell line was stained with Mouse Anti-Human TROP-2 Monoclonal Antibody. 100 μg Log in to see 8 to 9 Days
$294.00
Details
Mouse Goat Allophycocyanin FACS Detection of TROP-2 in XB2 Mouse Cell Line by Flow Cytometry. XB2 mouse teratoma keratinocyte cell line was stained with Goat Anti-Mouse TROP-2 APC-conjugated Antigen Affinity-purified Polyclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$367.50
Details
Human Goat Un-conjugated FACS, IHC, WB Detection of TROP-2 in PC-3 Human Cell Line by Flow Cytometry. PC-3 human prostate cancer cell line was stained with Goat Anti-Human TROP-2 Antigen Affinity-purified Polyclonal Antibody. TROP-2 in Human Brain. TROP-2 was detected in immersion fixed paraffin-embedded sections of human brain (frontal cortex) using Goat Anti-Human TROP-2 Antigen Affinity-purified Polyclonal Antibody. 100 μg Log in to see 8 to 9 Days
$388.50
Details
Mouse Goat Un-conjugated FACS, ICC, IHC, WB Detection of TROP-2 in XB2 Mouse Cell Line by Flow Cytometry. XB2 mouse teratoma keratinocyte cell line was stained with Goat Anti-Mouse TROP-2 Antigen Affinity-purified Polyclonal Antibody. TROP-2 in XB2 Mouse Cell Line. TROP-2 was detected in immersion fixed XB2 mouse teratoma keratinocyte cell line using Goat Anti-Mouse TROP-2 Antigen Affinity-purified Polyclonal Antibody. 100 μg Log in to see 8 to 9 Days
$393.75
Details
Human Goat Un-conjugated ELISA, WB Western Blot: TROP-2 Antibody [NBP1-05036] - (0.2ug/ml) staining of Human Prostate lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of TROP2 antibody (Center) (ABIN390632) in HL60 cell line lysates (35 µg/lane). TROP2 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human prostate carcinoma with TROP2 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details

TACSTD2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-TACSTD2 Antibodies

  1. Human Polyclonal TACSTD2 Primary Antibody for FACS, IHC - ABIN4900496 : Ambrogi, Fornili, Boracchi, Trerotola, Relli, Simeone, La Sorda, Lattanzio, Querzoli, Pedriali, Piantelli, Biganzoli, Alberti: Trop-2 is a determinant of breast cancer survival. in PLoS ONE 2014 (PubMed)
    Show all 8 references for 4900496

  2. Mouse (Murine) Polyclonal TACSTD2 Primary Antibody for FACS, ICC - ABIN4900492 : Eisenwort, Jurkin, Yasmin, Bauer, Gesslbauer, Strobl: Identification of TROP2 (TACSTD2), an EpCAM-like molecule, as a specific marker for TGF-?1-dependent human epidermal Langerhans cells. in The Journal of investigative dermatology 2011 (PubMed)
    Show all 5 references for 4900492

  3. Human Monoclonal TACSTD2 Primary Antibody for FACS, WB - ABIN4900015 : Yamaguchi, Nishii, Nakamura, Aoki, Hirai, Uchida, Sakuma, Hamada: Development of a sensitive screening method for selecting monoclonal antibodies to be internalized by cells. in Biochemical and biophysical research communications 2016 (PubMed)
    Show all 3 references for 4900015

  4. Human Monoclonal TACSTD2 Primary Antibody for FACS - ABIN4897042 : Hussain, Lawrence, Taylor, Lo, Frydenberg, Ellem, Furic, Risbridger: Estrogen receptor β activation impairs prostatic regeneration by inducing apoptosis in murine and human stem/progenitor enriched cell populations. in PLoS ONE 2012 (PubMed)
    Show all 2 references for 4897042

  5. Human Polyclonal TACSTD2 Primary Antibody for ELISA, WB - ABIN316346 : Shimada, Kano, Ishiyama, Okubo, Iijima, Morishita, Minami, Inadome, Shu, Sugita, Takeuchi, Noguchi: Establishment of an immortalized cell line from a precancerous lesion of lung adenocarcinoma, and genes highly expressed in the early stages of lung adenocarcinoma development. in Cancer science 2005 (PubMed)

  6. Mouse (Murine) Polyclonal TACSTD2 Primary Antibody for FACS - ABIN4897799 : Stoyanova, Goldstein, Cai, Drake, Huang, Witte: Regulated proteolysis of Trop2 drives epithelial hyperplasia and stem cell self-renewal via β-catenin signaling. in Genes & development 2012 (PubMed)

  7. Human Polyclonal TACSTD2 Primary Antibody for EIA, WB - ABIN453439 : Goldstein, Lawson, Cheng, Sun, Garraway, Witte: Trop2 identifies a subpopulation of murine and human prostate basal cells with stem cell characteristics. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)

More Antibodies against TACSTD2 Interaction Partners

Mouse (Murine) Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) interaction partners

  1. Trop-2 promotes an alpha5beta1 integrin-dependent pro-metastatic signaling pathway in PCa (show ENPP1 Antibodies) cells and that the altered expression of Trop-2 may be utilized for early identification of capsule-invading PCa (show ENPP1 Antibodies).

  2. studies have begun to identify the mechanisms underlying TROP2's functions, including regulated intramembrane proteolysis or specific interactions with integrin b1 and claudin proteins.

  3. our findings help to establish a close functional link between Trop2 and MSCs, and to provide a tool for future investigation of Trop2 in other types of stem cells

  4. data suggest that Trop2 regulates cell proliferation and motility and that it does so by regulating the ERK (show EPHB2 Antibodies) pathway and several critical components of the cell migration apparatus

  5. Trop2 plays a cardioprotective role by promoting cardiac c-kit (show KIT Antibodies)+ cell proliferation and inhibition of apoptosis in the acute phase of myocardial infarction.

  6. Trop2 is a regulator of self-renewal, proliferation, and transformation

  7. TROP2 modulates the interaction between the cells and matrix and regulates the formation of the ureteric duct by suppressing branching from the trunk during kidney development.

  8. these results uncover a role for Trop2 loss in tumorigenesis and the mesenchymal transdifferentiation observed in a subset of squamous cell carcinomas.

  9. In human and mouse, Trop2 is highly expressed at both the transcript and protein levels on several essential normal tissues.

  10. Study also provides the first indication of a molecular signaling pathway activated by Trop2 which has important implications for cancer cell growth and survival.

Human Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) interaction partners

  1. TROP2 was overexpressed specifically in the majority of epithelial ovarian cancer and may be a novel prognostic biomarker

  2. we compared the diagnostic value of TROP-2 expression in distinguishing between benign and malignant thyroid lesions to those of HBME-1, CK19 (show KRT19 Antibodies) and galectin-3 (show LGALS3 Antibodies)

  3. TROP-2 membranous staining is a very sensitive and specific marker for the classic and tall cell variants of papillary thyroid carcinoma, and for papillary microcarcinomas , with high overall specificity for papillary thyroid carcinoma

  4. The results suggested that trop2 facilitated neovascularization of non-small-cell lung cancer via activating ERK1/2 (show MAPK1/3 Antibodies) signaling pathway.

  5. We identified a homozygous TACSTD2 missense mutation, c.551A>G, p.(Tyr184Cys), in the affected family members. Both parents were heterozygous for the mutation, and unaffected siblings were either heterozygous or homozygous wild-type for this allele.

  6. Our results expand the mutational spectrum of TACSTD2 in patients with gelatinous drop-like corneal dystrophy (GDLD).

  7. Trop2 expression was higher in GC tissues than in neighboring non-tumor tissues. Increased Trop2 protein levels in GC were associated with increased differentiation, tumor node metastasis stage, tumor size, lymph node metastasis, distant metastasis, and H. pylori infection.

  8. Trop-2 is a novel target for ADC (show ADC Antibodies) therapy because of its high expression by many solid cancers.

  9. TROP2 is epigenetically down-regulated and operates as a negative regulator of cell proliferation and migration in liver fluke-associated cholangiocarcinoma.

  10. TROP-2 is specifically expressed in papillary thyroid carcinoma.

TACSTD2 Antigen Profile

Protein Summary

This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.

Gene names and symbols associated with TACSTD2

  • tropomyosin 2, beta (Tpm2) antibody
  • tumor-associated calcium signal transducer 2 (TACSTD2) antibody
  • tumor-associated calcium signal transducer 2 (Tacstd2) antibody
  • C80403 antibody
  • EGP-1 antibody
  • EGP1 antibody
  • GA733-1 antibody
  • GA7331 antibody
  • GP50 antibody
  • Ly97 antibody
  • M1S1 antibody
  • Prp1 antibody
  • Tpm-2 antibody
  • Trop-2 antibody
  • TROP2 antibody

Protein level used designations for TACSTD2

tropomyosin beta chain , 40kD glycoprotein, identified by monoclonal antibody GA733 , cell surface glycoprotein TROP2 , cell surface glycoprotein Trop-2 , epithelial glycoprotein-1 , gastrointestinal tumor-associated antigen GA7331 , membrane component chromosome 1 surface marker 1 , membrane component, chromosome 1, surface marker 1 , pancreatic carcinoma marker protein GA733-1 , pancreatic carcinoma marker protein GA7331 , lymphocyte antigen 97 , tunor-associated calcium signal transducer 2 , parturition-related protein 1

GENE ID SPECIES
22004 Mus musculus
4070 Homo sapiens
56753 Mus musculus
494343 Rattus norvegicus
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