Tumor-Associated Calcium Signal Transducer 2 Proteins (TACSTD2)

This intronless gene encodes a carcinoma-associated antigen. Additionally we are shipping TACSTD2 Antibodies (176) and TACSTD2 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TACSTD2 22004 P58774
TACSTD2 4070 P09758
TACSTD2 494343 Q6P9Z6
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Top TACSTD2 Proteins at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 20 to 21 Days
$250.80
Details
HOST_Human Cells Human Fc Tag,His tag 100 μg Log in to see 20 to 21 Days
$250.80
Details
HOST_Human Cells Human His tag 100 μg Log in to see 20 to 21 Days
$250.80
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$319.00
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,244.78
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_HEK-293 Cells Human His tag Human TROP-2, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 200 μg Log in to see 21 to 31 Days
$275.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,629.00
Details

TACSTD2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , ,
, , ,
Human , , , ,
, , , , ,
Rat (Rattus)

Top referenced TACSTD2 Proteins

  1. Human TACSTD2 Protein expressed in Human Cells - ABIN2002832 : Fornaro, DellArciprete, Stella, Bucci, Nutini, Capri, Alberti: Cloning of the gene encoding Trop-2, a cell-surface glycoprotein expressed by human carcinomas. in International journal of cancer. Journal international du cancer 1995 (PubMed)
    Show all 4 references for 2002832

  2. Human TACSTD2 Protein expressed in Human Cells - ABIN2002830 : Ripani, Sacchetti, Corda, Alberti: Human Trop-2 is a tumor-associated calcium signal transducer. in International journal of cancer. Journal international du cancer 1998 (PubMed)
    Show all 4 references for 2002830

  3. Mouse (Murine) TACSTD2 Protein expressed in Human Cells - ABIN2008414 : Linnenbach, Seng, Wu, Robbins, Scollon, Pyrc, Druck, Huebner: Retroposition in a family of carcinoma-associated antigen genes. in Molecular and cellular biology 1993 (PubMed)
    Show all 4 references for 2008414

  4. Human TACSTD2 Protein expressed in Escherichia coli (E. coli) - ABIN1098749 : Tasa, Kals, Muru, Juronen, Piirsoo, Veromann, Jänes, Mikelsaar, Lang: A novel mutation in the M1S1 gene responsible for gelatinous droplike corneal dystrophy. in Investigative ophthalmology & visual science 2001 (PubMed)
    Show all 2 references for 1098749

More Proteins for Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) Interaction Partners

Mouse (Murine) Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) interaction partners

  1. Trop-2 promotes an alpha5beta1 integrin-dependent pro-metastatic signaling pathway in PCa (show ENPP1 Proteins) cells and that the altered expression of Trop-2 may be utilized for early identification of capsule-invading PCa (show ENPP1 Proteins).

  2. studies have begun to identify the mechanisms underlying TROP2's functions, including regulated intramembrane proteolysis or specific interactions with integrin b1 and claudin proteins.

  3. our findings help to establish a close functional link between Trop2 and MSCs, and to provide a tool for future investigation of Trop2 in other types of stem cells

  4. data suggest that Trop2 regulates cell proliferation and motility and that it does so by regulating the ERK (show EPHB2 Proteins) pathway and several critical components of the cell migration apparatus

  5. Trop2 plays a cardioprotective role by promoting cardiac c-kit+ cell proliferation and inhibition of apoptosis in the acute phase of myocardial infarction.

  6. Trop2 is a regulator of self-renewal, proliferation, and transformation

  7. TROP2 modulates the interaction between the cells and matrix and regulates the formation of the ureteric duct by suppressing branching from the trunk during kidney development.

  8. these results uncover a role for Trop2 loss in tumorigenesis and the mesenchymal transdifferentiation observed in a subset of squamous cell carcinomas.

  9. In human and mouse, Trop2 is highly expressed at both the transcript and protein levels on several essential normal tissues.

  10. Study also provides the first indication of a molecular signaling pathway activated by Trop2 which has important implications for cancer cell growth and survival.

Human Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) interaction partners

  1. TROP2 was overexpressed specifically in the majority of epithelial ovarian cancer and may be a novel prognostic biomarker

  2. we compared the diagnostic value of TROP-2 expression in distinguishing between benign and malignant thyroid lesions to those of HBME-1, CK19 (show KRT19 Proteins) and galectin-3 (show LGALS3 Proteins)

  3. TROP-2 membranous staining is a very sensitive and specific marker for the classic and tall cell variants of papillary thyroid carcinoma, and for papillary microcarcinomas , with high overall specificity for papillary thyroid carcinoma

  4. The results suggested that trop2 facilitated neovascularization of non-small-cell lung cancer via activating ERK1/2 signaling pathway.

  5. We identified a homozygous TACSTD2 missense mutation, c.551A>G, p.(Tyr184Cys), in the affected family members. Both parents were heterozygous for the mutation, and unaffected siblings were either heterozygous or homozygous wild-type for this allele.

  6. Our results expand the mutational spectrum of TACSTD2 in patients with gelatinous drop-like corneal dystrophy (GDLD).

  7. Trop2 expression was higher in GC tissues than in neighboring non-tumor tissues. Increased Trop2 protein levels in GC were associated with increased differentiation, tumor node metastasis stage, tumor size, lymph node metastasis, distant metastasis, and H. pylori infection.

  8. Trop-2 is a novel target for ADC (show ADC Proteins) therapy because of its high expression by many solid cancers.

  9. TROP2 is epigenetically down-regulated and operates as a negative regulator of cell proliferation and migration in liver fluke-associated cholangiocarcinoma.

  10. TROP-2 is specifically expressed in papillary thyroid carcinoma.

TACSTD2 Protein Profile

Protein Summary

This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.

Gene names and symbols associated with TACSTD2

  • tropomyosin 2, beta (Tpm2)
  • tumor-associated calcium signal transducer 2 (TACSTD2)
  • tumor-associated calcium signal transducer 2 (Tacstd2)
  • C80403 protein
  • EGP-1 protein
  • EGP1 protein
  • GA733-1 protein
  • GA7331 protein
  • GP50 protein
  • Ly97 protein
  • M1S1 protein
  • Prp1 protein
  • Tpm-2 protein
  • Trop-2 protein
  • TROP2 protein

Protein level used designations for TACSTD2

tropomyosin beta chain , 40kD glycoprotein, identified by monoclonal antibody GA733 , cell surface glycoprotein TROP2 , cell surface glycoprotein Trop-2 , epithelial glycoprotein-1 , gastrointestinal tumor-associated antigen GA7331 , membrane component chromosome 1 surface marker 1 , membrane component, chromosome 1, surface marker 1 , pancreatic carcinoma marker protein GA733-1 , pancreatic carcinoma marker protein GA7331 , lymphocyte antigen 97 , tunor-associated calcium signal transducer 2 , parturition-related protein 1

GENE ID SPECIES
22004 Mus musculus
4070 Homo sapiens
56753 Mus musculus
494343 Rattus norvegicus
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