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TTYH1 encodes a member of the tweety family of proteins. Additionally we are shipping TTYH1 Antibodies (38) and TTYH1 Proteins (8) and many more products for this protein.
In this report, we identify tweety-homolog 1 (Ttyh1), a membrane protein linked to neuronal development, as a potent driver of tumor microtube (TM)-mediated brain colonization by glioma cells.
Ttyh1 plays an indispensable role during mitosis in early embryogenesis, possibly by maintaining Ca(2 (show CA2 ELISA Kits)+) homeostasis in the ER.
TTYH1 was not expressed in either the malignant or the control samples
Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific (show CALY ELISA Kits) DNMT3B (show DNMT3B ELISA Kits) isoform in the embryonal brain tumor.
Nedd4-2 differentially interacts with and regulates TTYH1-3
While ttyh1 is restricted to proliferative, ventricular zones, ttyh3 (show TTYH3 ELISA Kits) is primarily localized to postmitotic regions of the developing nervous system.
This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-independent, volume-sensitive large conductance chloride(-) channel. Three transcript variants encoding distinct isoforms have been identified for this gene.
, protein tweety homolog 1
, tweety homolog 1 (Drosophila)
, tweety 1
, protein tweety homolog 1-A