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TDP1 Proteins

(Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform. [provided by RefSeq, Jul 2008].
TDP1 Protein (AA 1-608) (GST tag) TDP1 Protein (AA 1-608) (GST tag) TDP1 Protein (AA 1-608) (GST tag) (ABIN1322434)

TDP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

TDP1 Protein (AA 121-218) (GST tag) TDP1 Protein (AA 121-218) (GST tag) TDP1 Protein (AA 121-218) (GST tag) (ABIN1322436)

TDP1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

TDP1 Protein (AA 1-608) (His tag) TDP1 Protein (AA 1-608) (His tag) TDP1 Protein (AA 1-608) (His tag) (ABIN3096148)

Crystallography grade TDP1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys

TDP1 Proteins by Grade

Find TDP1 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

TDP1 Proteins by Origin

Find TDP1 Proteins for a variety of species such as anti-Human TDP1, anti-Rat TDP1, anti-Mouse TDP1. The species listed below are among those available. Click on a link to go to the corresponding products.

TDP1 Proteins by Source

Here you will find TDP1 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

TDP1 Proteins by Protein Type

Here you can find TDP1 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

TDP1 Proteins by Application

Find TDP1 Proteins validated for a specific application such as WB, ELISA, SDS, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular TDP1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1322434
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1322436
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3096148
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136184
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7419694
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7420363
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7423144
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN6119431
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2733393
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2733392
Quantity 20 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1616638
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our TDP1 Proteins

Takahashi, Tada, Igarashi, Koyama, Date, Yokoseki, Shiga, Yoshida, Tsuji, Nishizawa, Onodera: "Aprataxin, causative gene product for EAOH/AOA1, repairs DNA single-strand breaks with damaged 3'-phosphate and 3'-phosphoglycolate ends." in: Nucleic acids research, Vol. 35, Issue 11, pp. 3797-809, (2007) (PubMed).

Aliases for TDP1 Proteins

tyrosyl-DNA phosphodiesterase 1 (TDP1) Proteins
tyrosyl-DNA Phosphodiesterase (Tdp1) (Tc00.1047053511191.10) Proteins
tyrosyl-DNA phosphodiesterase 1 (Tdp1) Proteins
tyrosyl-DNA phosphodiesterase 1 L homeolog (tdp1.L) Proteins
tyrosyl-DNA phosphodiesterase 1 (tdp1) Proteins
tyrosyl-DNA phosphodiesterase-like protein (TDP1) Proteins
tyrosyl-DNA phosphodiesterase 1 (PTRG_11198) Proteins
tyrosyl-DNA phosphodiesterase 1 (MCYG_02121) Proteins
tyrosyl-DNA phosphodiesterase 1 (MGYG_03035) Proteins
2810481F14Rik Proteins
4921509N21Rik Proteins
AI838772 Proteins
AW493413 Proteins
E430034L06Rik Proteins
F8M21.60 Proteins
F8M21_60 Proteins
MGC83708 Proteins
MLZ-501 Proteins
SCAN1 Proteins
tdp1 Proteins
TDP1 Proteins
tyrosyl-DNA phosphodiesterase 1 Proteins
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