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U2 Small Nuclear RNA Auxiliary Factor 1-Like 4 Proteins (U2AF1L4)

RNA-binding protein that function as a pre-mRNA splicing factor.

list all proteins Gene Name GeneID UniProt
Human U2AF1L4 U2AF1L4 199746 Q8WU68
Mouse U2AF1L4 U2AF1L4 233073 Q8BGJ9
Rat U2AF1L4 U2AF1L4 361542 Q7TP17
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More Proteins for U2 Small Nuclear RNA Auxiliary Factor 1-Like 4 (U2AF1L4) Interaction Partners

Human U2 Small Nuclear RNA Auxiliary Factor 1-Like 4 (U2AF1L4) interaction partners

  1. U2AF1L4 (show TMEM149 Proteins) gene expression is regulated by cytokines in activated T cells.

  2. a 269 bp region located between the PSENEN (show PSENEN Proteins) and U2AF1L4 (show TMEM149 Proteins) human genes is a genuine bidirectional promoter regulating a concerted divergent transcription of these genes.

  3. Differential isoform expression and interaction with the P32 (show C1QBP Proteins) regulatory protein controls the subcellular localization of the splicing factor (show SLU7 Proteins) U2AF26

Mouse (Murine) U2 Small Nuclear RNA Auxiliary Factor 1-Like 4 (U2AF1L4) interaction partners

  1. Data suggest light-induced U2af26 alternative splicing to be a buffering mechanism that limits PERIOD1 induction, thus stabilizing the circadian clock against abnormal changes in light:dark conditions.

  2. Differential isoform expression and interaction with the P32 (show C1QBP Proteins) regulatory protein (show TGFB1 Proteins) controls the subcellular localization of the splicing factor (show SLU7 Proteins) U2AF26

U2 Small Nuclear RNA Auxiliary Factor 1-Like 4 (U2AF1L4) Protein Profile

Protein Summary

RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer- dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation\; an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site (By similarity).

Gene names and symbols associated with U2AF1L4

  • U2 small nuclear RNA auxiliary factor 1-like 4 (U2AF1L4)
  • U2 small nuclear RNA auxiliary factor 1-like 4 (LOC100347194)
  • U2 small nuclear RNA auxiliary factor 1-like 4 (U2af1l4)
  • AA407033 protein
  • AF419339 protein
  • AI451269 protein
  • AW553050 protein
  • TMEM149 protein
  • U2AF1-RS3 protein
  • U2AF1L3 protein
  • U2AF1L3V1 protein
  • U2AF1RS3 protein
  • U2af26 protein

Protein level used designations for U2AF1L4

U2 small nuclear RNA auxiliary factor 1-like 4 , transmembrane protein 149 , U2 auxiliary factor 26 , U2 small nuclear RNA auxiliary factor 1-like 3 , U2 small nuclear RNA auxiliary factor 1-like protein 3 , U2 small nuclear RNA auxiliary factor 1-like protein 4 , U2(RNU2) small nuclear RNA auxiliary factor 1-like 3 , U2(RNU2) small nuclear RNA auxiliary factor 1-like protein 3 , U2AF1-like protein 3 , splicing factor U2AF 26 kDa subunit , auxiliary factor 26 , Cb2-807 , liver regeneration-related protein LRRG157/LRRG158

GENE ID SPECIES
455961 Pan troglodytes
100347194 Oryctolagus cuniculus
199746 Homo sapiens
476480 Canis lupus familiaris
233073 Mus musculus
361542 Rattus norvegicus
615198 Bos taurus
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