UBX Domain Protein 1 (UBXN1) ELISA Kits

Ubiquitin-binding protein that interacts with the BRCA1- BARD1 heterodimer, and regulates its activity. Additionally we are shipping UBX Domain Protein 1 Antibodies (21) and UBX Domain Protein 1 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human UBXN1 UBXN1 51035 Q04323
Anti-Mouse UBXN1 UBXN1 225896 Q922Y1
Anti-Rat UBXN1 UBXN1 293719  
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More ELISA Kits for UBX Domain Protein 1 Interaction Partners

Human UBX Domain Protein 1 (UBXN1) interaction partners

  1. The ability of UBXN1 and other family members to negatively regulate the NFkappaB pathway may be important for dampening the host immune response in disease processes and also re-activating quiescent HIV from latent viral reservoirs in chronically infected individuals

  2. p47 (show ING1 ELISA Kits) promotes, whereas SASK1 delays the degradation of a single ERAD substrate, alpha-TCR. Additionally, we found that SAKS1 selectively inhibits the degradation of ERAD substrates without affecting cytosolic proteasomal substrates.

  3. UBXN1 is a negative regulator of NF-kappaB (show NFKB1 ELISA Kits) signaling.

  4. UBXN1 is induced and recruited to MAVS (show MAVS ELISA Kits) after virus infection, serving as a brake to prevent excessive RLR (show DHX58 ELISA Kits) signaling, most likely at a late stage of infection.

  5. SAKS1 inhibits protein degradation mediated by p97 complexes in the cytosol with a component of the mechanism being the ability to shield polyubiquitin chains from ubiquitin-processing factors.

  6. Data suggest that UBXN1 regulates the enzymatic function of BRCA1 in a manner that is dependent on its ubiquitination status.

  7. Specific interaction of rat protein 2B28 with rat Homer2 (show HOMER2 ELISA Kits) may play a role in regulation of protein degradation by ubiquitin-proteasome systems and that this function may be specific to Homer2 (show HOMER2 ELISA Kits) proteins among Homer (show HOMER1 ELISA Kits) family proteins.

Mouse (Murine) UBX Domain Protein 1 (UBXN1) interaction partners

  1. Specific interaction of rat protein 2B28 with rat Homer2 (show HOMER2 ELISA Kits) may play a role in regulation of protein degradation by ubiquitin-proteasome systems and that this function may be specific to Homer2 (show HOMER2 ELISA Kits) proteins among Homer (show HOMER1 ELISA Kits) family proteins.

UBX Domain Protein 1 (UBXN1) Antigen Profile

Antigen Summary

Ubiquitin-binding protein that interacts with the BRCA1- BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulun that are retrotranslocated in the cytosol.

Gene names and symbols associated with UBX Domain Protein 1 (UBXN1) ELISA Kits

  • UBX domain protein 1 (UBXN1) antibody
  • UBX domain protein 1 (Ubxn1) antibody
  • UBX domain protein 1 (ubxn1) antibody
  • 2B28 antibody
  • 4930455J02Rik antibody
  • D19Ertd721e antibody
  • fb49a05 antibody
  • RGD1309471 antibody
  • SAKS1 antibody
  • T25529 antibody
  • UBXD10 antibody
  • wu:fb49a05 antibody
  • zgc:77531 antibody

Protein level used designations for UBX Domain Protein 1 (UBXN1) ELISA Kits

SAPK substrate protein 1 , UBA/UBX 33.3 kDa protein , UBX domain-containing protein 1 , mY33K , protein 2B28

GENE ID SPECIES
51035 Homo sapiens
225896 Mus musculus
293719 Rattus norvegicus
506676 Bos taurus
322073 Danio rerio
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