UBX Domain Protein 1 Proteins (UBXN1)

Ubiquitin-binding protein that interacts with the BRCA1- BARD1 heterodimer, and regulates its activity. Additionally we are shipping UBX Domain Protein 1 Antibodies (21) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
UBXN1 51035 Q04323
Mouse UBXN1 UBXN1 225896 Q922Y1
UBXN1 293719  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top UBX Domain Protein 1 Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 60 to 71 Days
$2,755.50
Details
Yeast Zebrafish His tag   1 mg Log in to see 60 to 71 Days
$2,777.50
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,784.83
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$2,784.83
Details

UBXN1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Rat (Rattus)

More Proteins for UBX Domain Protein 1 (UBXN1) Interaction Partners

Human UBX Domain Protein 1 (UBXN1) interaction partners

  1. The ability of UBXN1 and other family members to negatively regulate the NFkappaB pathway may be important for dampening the host immune response in disease processes and also re-activating quiescent HIV from latent viral reservoirs in chronically infected individuals

  2. p47 (show ING1 Proteins) promotes, whereas SASK1 delays the degradation of a single ERAD substrate, alpha-TCR. Additionally, we found that SAKS1 selectively inhibits the degradation of ERAD substrates without affecting cytosolic proteasomal substrates.

  3. UBXN1 is a negative regulator of NF-kappaB (show NFKB1 Proteins) signaling.

  4. UBXN1 is induced and recruited to MAVS (show MAVS Proteins) after virus infection, serving as a brake to prevent excessive RLR (show DHX58 Proteins) signaling, most likely at a late stage of infection.

  5. SAKS1 inhibits protein degradation mediated by p97 complexes in the cytosol with a component of the mechanism being the ability to shield polyubiquitin chains from ubiquitin-processing factors.

  6. Data suggest that UBXN1 regulates the enzymatic function of BRCA1 in a manner that is dependent on its ubiquitination status.

  7. Specific interaction of rat protein 2B28 with rat Homer2 (show HOMER2 Proteins) may play a role in regulation of protein degradation by ubiquitin-proteasome systems and that this function may be specific to Homer2 (show HOMER2 Proteins) proteins among Homer (show HOMER1 Proteins) family proteins.

Mouse (Murine) UBX Domain Protein 1 (UBXN1) interaction partners

  1. Specific interaction of rat protein 2B28 with rat Homer2 (show HOMER2 Proteins) may play a role in regulation of protein degradation by ubiquitin-proteasome systems and that this function may be specific to Homer2 (show HOMER2 Proteins) proteins among Homer (show HOMER1 Proteins) family proteins.

UBX Domain Protein 1 (UBXN1) Protein Profile

Protein Summary

Ubiquitin-binding protein that interacts with the BRCA1- BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulun that are retrotranslocated in the cytosol.

Gene names and symbols associated with UBX Domain Protein 1 Proteins (UBXN1)

  • UBX domain protein 1 (UBXN1)
  • UBX domain protein 1 (Ubxn1)
  • UBX domain protein 1 (ubxn1)
  • 2B28 protein
  • 4930455J02Rik protein
  • D19Ertd721e protein
  • fb49a05 protein
  • RGD1309471 protein
  • SAKS1 protein
  • T25529 protein
  • UBXD10 protein
  • wu:fb49a05 protein
  • zgc:77531 protein

Protein level used designations for UBX Domain Protein 1 Proteins (UBXN1)

SAPK substrate protein 1 , UBA/UBX 33.3 kDa protein , UBX domain-containing protein 1 , mY33K , protein 2B28

GENE ID SPECIES
51035 Homo sapiens
225896 Mus musculus
293719 Rattus norvegicus
506676 Bos taurus
322073 Danio rerio
Selected quality suppliers for UBX Domain Protein 1 Proteins (UBXN1)
Did you look for something else?