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UBX Domain Protein 6 (UBXN6) ELISA Kits

Acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. Additionally we are shipping UBXN6 Antibodies (41) and UBXN6 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat UBXN6 UBXN6 363332  
Anti-Human UBXN6 UBXN6 80700 Q9BZV1
Anti-Mouse UBXN6 UBXN6 66530 Q99PL6
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More ELISA Kits for UBXN6 Interaction Partners

Human UBX Domain Protein 6 (UBXN6) interaction partners

  1. UBXD1-N intercalates into the p97 (show EIF4G2 ELISA Kits)-ND1 (show MT-ND1 ELISA Kits) interface, thereby modulating interdomain communication of p97 (show EIF4G2 ELISA Kits) domains and its activity with relevance for disease pathogenesis

  2. Data indicate that endosomal trafficking of CAV1 (show CAV1 ELISA Kits) depends on ubiquitination of the N-terminal region and the subsequent recruitment of VCP (show vcp ELISA Kits)-UBXD1.

  3. UBXD1 modulates the trafficking of ERGIC-53 (show LMAN1 ELISA Kits)-containing vesicles by controlling the interaction of transport factors with the cytoplasmic tail of ERGIC-53 (show LMAN1 ELISA Kits).

  4. Data show that expression of VCP (show vcp ELISA Kits) mutant proteins, or siRNA-mediated depletion of UBXD1 leads to a block of CAV1 (show CAV1 ELISA Kits) transport at the limiting membrane of enlarged endosomes in cultured cells.

  5. UBXD1 is a novel co-factor of the human p97 ATPase (show vcp ELISA Kits).

  6. An additional p97 (show EIF4G2 ELISA Kits) binding site in UBXD1 that competed with the p47 (show ING1 ELISA Kits) cofactor for binding to the N domain of p97 (show EIF4G2 ELISA Kits) was identified.

  7. these findings suggest that UBXD1 is a regulatory component of endoplasmic reticulum-associated degradation that may modulate the adaptor binding to VCP.

UBXN6 Antigen Profile

Antigen Summary

Acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. MDM2 stabilization leads to MDM2-dependent TP53 degradation (By similarity).

Gene names and symbols associated with UBX Domain Protein 6 (UBXN6) ELISA Kits

  • UBX domain protein 6 (Ubxn6) antibody
  • UBX domain protein 6 (UBXN6) antibody
  • 1200008L11Rik antibody
  • 2210415J11Rik antibody
  • AU040909 antibody
  • UBXD1 antibody
  • Ubxdc2 antibody

Protein level used designations for UBX Domain Protein 6 (UBXN6) ELISA Kits

UBX domain containing 1 , UBX domain-containing protein 6 , UBX domain protein 6 , UBX domain-containing 1 , UBX domain-containing 2 , UBX domain-containing protein 1

GENE ID SPECIES
363332 Rattus norvegicus
715070 Macaca mulatta
100018491 Monodelphis domestica
100589901 Nomascus leucogenys
80700 Homo sapiens
66530 Mus musculus
507936 Bos taurus
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