anti-UBX Domain Protein 6 (UBXN6) Antibodies

Acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. Additionally we are shipping UBXN6 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
UBXN6 363332  
UBXN6 80700 Q9BZV1
UBXN6 66530 Q99PL6
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Top anti-UBXN6 Antibodies at antibodies-online.com

Showing 10 out of 44 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-UBXN6 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>Human Muscle WB Suggested Anti-UBXN6 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500 <br /> Positive Control: Human Muscle 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of UBXN6 Antibody (C-term) (ABIN651276) in mouse kidney tissue lysates (35 µg/lane).UBXN6 (arrow) was detected using the purified polyclonal antibody. UBXN6 Antibody (C-term) (ABIN651276) IHC analysis in formalin fixed and paraffin embedded mouse testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Mouse Un-conjugated IF, IP, WB   50 μg Log in to see 6 to 7 Days
$386.93
Details
Human Mouse Un-conjugated IF, IP, WB   50 μg Log in to see 6 to 7 Days
$386.93
Details
Human Rabbit Un-conjugated ICC, IF, WB Western Blot: UBXN6 Antibody  - Western blot analysis in human cell line RT-4 and human cell line U-251 MG. Immunocytochemistry/Immunofluorescence: UBXN6 Antibody  - Staining of human cell line HEK 293 shows localization to cytosol & the Golgi apparatus. 100 μL Log in to see 10 to 13 Days
$439.69
Details
Mouse Rabbit Un-conjugated WB Western Blot: UBXN6 Antibody [NBP1-98481] - Mouse Heart Lysate 1.0ug/ml, Gel Concentration: 12% 100 μL Log in to see 8 to 11 Days
$447.56
Details
Bat Rabbit Un-conjugated WB   50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, IHC, WB   200 μL Log in to see 7 to 9 Days
$793.83
Details

UBXN6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)


Human ,
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Mouse (Murine)
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More Antibodies against UBXN6 Interaction Partners

Human UBX Domain Protein 6 (UBXN6) interaction partners

  1. Upon damage, p97 (show EIF4G2 Antibodies) translocates to lysosomes and there cooperates with a distinct set of cofactors including UBXD1, PLAA (show PLAA Antibodies), and the deubiquitinating enzyme YOD1 (show YOD1 Antibodies), which we term ELDR components for Endo-Lysosomal Damage Response.

  2. UBXD1-N intercalates into the p97 (show EIF4G2 Antibodies)-ND1 (show MT-ND1 Antibodies) interface, thereby modulating interdomain communication of p97 (show EIF4G2 Antibodies) domains and its activity with relevance for disease pathogenesis

  3. Data indicate that endosomal trafficking of CAV1 (show CAV1 Antibodies) depends on ubiquitination of the N-terminal region and the subsequent recruitment of VCP (show vcp Antibodies)-UBXD1.

  4. UBXD1 modulates the trafficking of ERGIC-53 (show LMAN1 Antibodies)-containing vesicles by controlling the interaction of transport factors with the cytoplasmic tail of ERGIC-53 (show LMAN1 Antibodies).

  5. Data show that expression of VCP (show vcp Antibodies) mutant proteins, or siRNA-mediated depletion of UBXD1 leads to a block of CAV1 (show CAV1 Antibodies) transport at the limiting membrane of enlarged endosomes in cultured cells.

  6. UBXD1 is a novel co-factor of the human p97 ATPase (show vcp Antibodies).

  7. An additional p97 (show EIF4G2 Antibodies) binding site in UBXD1 that competed with the p47 (show ING1 Antibodies) cofactor for binding to the N domain of p97 (show EIF4G2 Antibodies) was identified.

  8. these findings suggest that UBXD1 is a regulatory component of endoplasmic reticulum-associated degradation that may modulate the adaptor binding to VCP.

UBXN6 Antigen Profile

Protein Summary

Acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. MDM2 stabilization leads to MDM2-dependent TP53 degradation (By similarity).

Gene names and symbols associated with UBXN6

  • UBX domain protein 6 (Ubxn6) antibody
  • UBX domain protein 6 (UBXN6) antibody
  • 1200008L11Rik antibody
  • 2210415J11Rik antibody
  • AU040909 antibody
  • UBXD1 antibody
  • Ubxdc2 antibody

Protein level used designations for UBXN6

UBX domain containing 1 , UBX domain-containing protein 6 , UBX domain protein 6 , UBX domain-containing 1 , UBX domain-containing 2 , UBX domain-containing protein 1

GENE ID SPECIES
363332 Rattus norvegicus
715070 Macaca mulatta
100018491 Monodelphis domestica
100589901 Nomascus leucogenys
80700 Homo sapiens
66530 Mus musculus
507936 Bos taurus
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