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UDP Glucuronosyltransferase 1 Family, Polypeptide A4 (UGT1A4) ELISA Kits

UGT1A4 encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. Additionally we are shipping UGT1A4 Antibodies (11) and UGT1A4 Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human UGT1A4 UGT1A4 54657 P22310
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More ELISA Kits for UGT1A4 Interaction Partners

Human UDP Glucuronosyltransferase 1 Family, Polypeptide A4 (UGT1A4) interaction partners

  1. Influence of valproic acid concentration and polymorphism of UGT1A4*3, UGT2B7 (show UGT2B7 ELISA Kits) -161C > T and UGT2B7 (show UGT2B7 ELISA Kits)*2 on serum concentration of lamotrigine in Chinese epileptic children

  2. This descriptive study examines correlations between concentrations of tamoxifen's glucuronide metabolites and genotypes UGT1A4, UGT2B7 (show UGT2B7 ELISA Kits), UGT2B15 (show UGT2B15 ELISA Kits) and UGT2B17 (show UGT2B17 ELISA Kits) in 132 patients with estrogen receptor (show ESR1 ELISA Kits)-positive breast cancer under treatment with tamoxifen

  3. in tumor liver microsomes from HCC (show FAM126A ELISA Kits) patients, either V(max) (maximum reaction rate, R(max) for UGT1A1 (show UGT1A1 ELISA Kits)) or clearance rates (V(max)/K(m), Clint (show CLINT1 ELISA Kits)) of UGT1A (show UGT1A1 ELISA Kits), UGT1A1 (show UGT1A1 ELISA Kits), UGT1A4, UGT1A9 (show UGT1A9 ELISA Kits) and UGT2B7 (show UGT2B7 ELISA Kits) were lower than those in the adjacent normal liver microsomes

  4. The association between the UGT1A4 promoter and coding region SNPs and the glucuronidation rates of Tam (show CCNA1 ELISA Kits).

  5. Correlation of the UGT1A4 gene polymorphism with serum concentration and therapeutic efficacy of lamotrigine in Han Chinese of Northern China

  6. Human UGT1A4 and UGT1A3 conjugate 25-hydroxyvitamin D3.

  7. the substrate specificity of UGT2B10, highlighting its preference for tertiary amines with higher affinities and clearance values than those of UGT1A4 and UGT1A3.

  8. Present results could be helpful to improve the use of UGT1A4 drug substrates in order to adjust them to the ethnic background of a given population, specifically for Hispanics.

  9. study to determine the allelic frequency of two most common defective alleles: UGT1A4*2 and UGT1A4*3 in a Jordanian population

  10. Polymorphic glucuronidation of olanzapine by uridine diphosphate glucuronosyltransferase 1A4 (UGT1A4) was investigated retrospectively in patient samples

UGT1A4 Antigen Profile

Antigen Summary

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. This enzyme has some glucuronidase activity towards bilirubin, although is is more active on amines, steroids, and sapogenins.

Gene names and symbols associated with UGT1A4

  • UDP glucuronosyltransferase 1 family, polypeptide A4 (UGT1A4) antibody
  • UDP-glucuronosyltransferase 1-4 (UGT1-4) antibody
  • HUG-BR2 antibody
  • UDPGT antibody
  • UDPGT 1-4 antibody
  • UGT-1D antibody
  • UGT1 antibody
  • UGT1-04 antibody
  • UGT1.4 antibody
  • UGT1A4 antibody
  • UGT1D antibody

Protein level used designations for UGT1A4

UDP glycosyltransferase 1 family, polypeptide A4 , UDP-glucuronosyltransferase 1-4 , UDP-glucuronosyltransferase 1-D , UDP-glucuronosyltransferase 1A4 , bilirubin UDP-glucuronosyltransferase isozyme 2 , bilirubin-specific UDPGT isozyme 2

GENE ID SPECIES
54657 Homo sapiens
100038310 Oryctolagus cuniculus
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