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UDP Glucuronosyltransferase 1 Family, Polypeptide A6 Proteins (UGT1A6)

UGT1A6 encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. Additionally we are shipping UDP Glucuronosyltransferase 1 Family, Polypeptide A6 Antibodies (17) and UDP Glucuronosyltransferase 1 Family, Polypeptide A6 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
UGT1A6 54578 P19224
Rat UGT1A6 UGT1A6 113992 P08430
Mouse UGT1A6 UGT1A6 94284 Q64435
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Top UDP Glucuronosyltransferase 1 Family, Polypeptide A6 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

UGT1A6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6) Interaction Partners

Human UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6) interaction partners

  1. Oxidative stress and histone modifications may promote transcriptional activation of Ugt1a6 and Ugt1a7 genes.

  2. Identified coding variants on UGT1A1 (show UGT1A1 Proteins) and UGT1A6 genes in association with serum bilirubin level and hyperbilirubinemia risk in elderly subjects.

  3. Results suggest that CYP3A4 (show CYP3A4 Proteins) changes the catalytic function of the UGT1A (show UGT1A1 Proteins) subfamily in a UGT (show SLC35A2 Proteins) isoform-specific manner.

  4. Evaluating the association of UGT1A6 2 Ser7Ala polymorphism with drug response, there was no significant difference in the genotypic distribution between responders and non-responders.

  5. Validation of variants in SLC28A3 (show SLC28A3 Proteins) and UGT1A6 as genetic markers predictive of anthracycline-induced cardiotoxicity in children.

  6. Lower adjusted plasma VPA concentrations were also observed in patients with UGT1A6 double heterozygosities than those with single heterozygosity.

  7. UGT1A6 polymorphisms may be used to identify people with increased risk of developing lung cancer

  8. Polymorphism in UDP-glucuronosyltransferase 1A6 is associated with colorectal cancer.

  9. Dual polymorphisms of UDP glucuronosyl-transferases 1A6 and 1A1 (show SLC45A2 Proteins) in a patient with Gilbert's syndrome who had persistent hyperserotoninemia that responded to octreotide are reported.

  10. analysis of UGT1A6 variants and aspirin use in a randomized trial of celecoxib for prevention of colorectal adenoma

Mouse (Murine) UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6) interaction partners

  1. the difference in expression levels between Ugt1a6a and Ugt1a6b in the hippocampus led us to speculate that Ugt1a6a is likely the predominant catalyst of serotonin glucuronidation in the mouse brain.

UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6) Protein Profile

Protein Summary

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.

Gene names and symbols associated with UGT1A6

  • UDP glucuronosyltransferase 1 family, polypeptide A6 (UGT1A6)
  • UDP glucuronosyltransferase 1 family, polypeptide A6 (ugt1a6)
  • UDP glucuronosyltransferase 1 family, polypeptide A1 (UGT1A1)
  • UDP glucuronosyltransferase 1 family, polypeptide A6 (Ugt1a6)
  • UDP glucuronosyltransferase 1 family, polypeptide A6A (Ugt1a6a)
  • UDP-glucuronosyltransferase 1-6 (UGT1-6)
  • DKFZP469F071 protein
  • GNT1 protein
  • HLUGP protein
  • HLUGP1 protein
  • Udpgt protein
  • UDPGT 1-6 protein
  • UGT protein
  • Ugt1 protein
  • UGT1-06 protein
  • UGT1.6 protein
  • UGT1A5 protein
  • Ugt1a6 protein
  • Ugt1a6b protein
  • UGT1A6S protein
  • Ugt1a7 protein
  • UGT1A8 protein
  • UGT1A9 protein
  • UGT1A10 protein
  • UGT1F protein

Protein level used designations for UGT1A6

UDP glycosyltransferase 1 family, polypeptide A6 , UDP-glucuronosyltransferase 1-6 , UDP glucuronosyltransferase 1 family, polypeptide A5 , UDP glycosyl transferase 1A6 , UDP glucuronosyltransferase 1 family, polypeptide A6 , UDP-glucuronosyltransferase 1-6-like , UDP-glucuronosyltransferase 1A6 , UDP glucuronosyltransferase 1 family, polypeptide A10 , UDP glucuronosyltransferase 1 family, polypeptide A7 , UDP glucuronosyltransferase 1 family, polypeptide A8 , UDP glucuronosyltransferase 1 family, polypeptide A9 , UDP-glucuronosyltransferase 1 family polypeptide A6s , UDP-glucuronosyltransferase 1-F , UGT-1F , UGT1*6 , UGT1-06 , UGT1.6 , phenol-metabolizing UDP-glucuronosyltransferase , A1 , P-nitrophenol specific , P-nitrophenol-specific UDPGT , UDP glucuronosyltransferase 1A6 , UDP-glucuronosyltransferase , phenol UDP-glucuronosyltransferase

GENE ID SPECIES
100172560 Pongo abelii
286792 Bos taurus
739942 Pan troglodytes
100126702 Papio anubis
100135191 Xenopus (Silurana) tropicalis
100384896 Danio rerio
100481084 Ailuropoda melanoleuca
100534643 Ovis aries
424028 Gallus gallus
54578 Homo sapiens
113992 Rattus norvegicus
100037183 Xenopus laevis
403629 Canis lupus familiaris
94284 Mus musculus
100037718 Oryctolagus cuniculus
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