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UDP Glucuronosyltransferase 2 Family, Polypeptide A1, Complex Locus Proteins (UGT2A1)

The protein encoded by UGT2A1 belongs to the UDP-glycosyltransferase family, members of which catalyze biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. Additionally we are shipping and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse UGT2A1 UGT2A1 94215 Q80X89
UGT2A1 63867 P36510
UGT2A1 10941 Q9Y4X1
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Top UGT2A1 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,325.67
Details

UGT2A1 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Human ,
,

More Proteins for UDP Glucuronosyltransferase 2 Family, Polypeptide A1, Complex Locus (UGT2A1) Interaction Partners

Human UDP Glucuronosyltransferase 2 Family, Polypeptide A1, Complex Locus (UGT2A1) interaction partners

  1. The Km values of UGT2A1 varied between 102.2 +/- 14.3 microM and 2.4 +/- 1.2 mM.

  2. Expression of novel UDP-glucuronosyltransferase 2A1 splice variant could play an important role in the detoxification of carcinogens within target tissues for tobacco carcinogenesis.

  3. Results show that UGT2A2 not only shares exons 2-6 with UGT2A1, it also shares with it a similar tissue expression pattern; both UGTs are primarily expressed in nasal epithelium. The 3rd member of UGT2A subfamily, UGT2A3 (show UGT2A3 Proteins) exhibited a different tissue expression pattern, found mainly in liver and small intestine.

  4. UGT2A1 is an important detoxification enzyme in the metabolism of polycyclic aromatic hydrocarbons.

  5. Single-nucleotide polymorphisms (SNPs) were found in UGT2A1 gene

UGT2A1 Protein Profile

Protein Summary

The protein encoded by this gene belongs to the UDP-glycosyltransferase family, members of which catalyze biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This enzyme is expressed in the olfactory neuroepithelium, which lines the posterior nasal cavity and is exposed to a wide range of odorants and airborne toxic compounds. Hence, this protein has been suggested to be involved in clearing lipophilic odorant molecules from the sensory epithelium. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with UGT2A1

  • UDP glucuronosyltransferase 2 family, polypeptide A1 (ugt2a1)
  • UDP glucuronosyltransferase 2 family, polypeptide A1 (Ugt2a1)
  • UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus (UGT2A1)
  • Ugt2a1p protein

Protein level used designations for UGT2A1

UDP glucuronosyltransferase 2 family, polypeptide A1 , UDP glycosyltransferase 2 family, polypeptide A1 , UDP-glucuronosyltransferase 2A1 , UDPGT 2A1 , olfactory UDP glucuronosyltransferase , UGT-OLF

GENE ID SPECIES
100006320 Danio rerio
94215 Mus musculus
63867 Rattus norvegicus
10941 Homo sapiens
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