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UDP Glycosyltransferase 8 Proteins (UGT8)

The protein encoded by UGT8 belongs to the UDP-glycosyltransferase family. Additionally we are shipping UDP Glycosyltransferase 8 Antibodies (52) and UDP Glycosyltransferase 8 Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
UGT8 22239 Q64676
UGT8 7368 Q16880
Rat UGT8 UGT8 50555 Q09426
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Top UDP Glycosyltransferase 8 Proteins at

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 0.5 mg Log in to see 49 to 54 Days
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 0.25 mg Log in to see 49 to 54 Days
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days

UGT8 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, ,

More Proteins for UDP Glycosyltransferase 8 (UGT8) Interaction Partners

Mouse (Murine) UDP Glycosyltransferase 8 (UGT8) interaction partners

  1. Our study showed that the additional deletion of Fa2h (show FA2H Proteins) does not obviously affect the phenotype of Cgt-/- mice. This suggests that HFA-GlcCer and HFA-sphingomyelin do not functionally compensate the loss of HFA-GalCer in Cgt-/- mice.

  2. Ugcg (show UGCG Proteins) and Ugt8a deficient oligodendroglial did not exhibit any phenotypic or myelin structural abnormalities; abundant and structurally intact myelin can form in their absence

  3. This study provides new insights into the changes that occur in the composition/distribution of myelin proteins in mice lacking ceramide galactosyltransferase.

  4. Our results indicate that loss of CGT in oligodendrocytes is exclusively responsible for the myelin structural deficits, demyelination, and behavioral abnormalities in CGT-deficient mice.

Human UDP Glycosyltransferase 8 (UGT8) interaction partners

  1. Our study suggests that CGT expression is controlled by balanced expression of the negative modulator OLIG2 (show OLIG2 Proteins) and positive regulator Nkx2.2 (show Nkx2-2 Proteins), providing new insights into how expression of GalCer is tightly regulated in cell-type- and stage-specific manners.

  2. A new role was identified for UGT8 as a modulator of bile acid homeostasis.

  3. High expression of UGT8 accompanied by accumulation of GalCer in MDA-MB-231 cells is associated with a much higher proliferative index and a lower number of apoptotic cells in comparison to the MDA/LUC-shUGT8 cells.

  4. Comprehensive genomic analyses associate UGT8 variants with musical ability in a Mongolian population.

  5. UGT8 is a significant index of tumour aggressiveness and is seen in lung metastases of breast cancer.

  6. Single-nucleotide polymorphisms (SNPs) were found in UGT8 gene

  7. We postulate that molecular link between defective GALT (show GALT Proteins) enzyme, which result in classic galactosemia and the cerebroside galactosyl transferase, responsible for galactosylation of cerebrosides, is dependent on concentrations of UDP-galactose (show B4GALT1 Proteins).

UDP Glycosyltransferase 8 (UGT8) Protein Profile

Protein Summary

The protein encoded by this gene belongs to the UDP-glycosyltransferase family. It catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central and peripheral nervous systems. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with UGT8

  • UDP glycosyltransferase 8 (UGT8)
  • UDP glycosyltransferase 8 (ugt8)
  • UDP galactosyltransferase 8A (Ugt8a)
  • UDP glycosyltransferase 8 (Ugt8)
  • AI850488 protein
  • AW455908 protein
  • CGT protein
  • mCerGT protein
  • UGT4 protein
  • Ugt8 protein
  • Ugt8a protein
  • Xlcgt protein

Protein level used designations for UGT8

UDP glycosyltransferase 8 (UDP-galactose ceramide galactosyltransferase) , UDP glycosyltransferase 8 , 2-hydroxyacylsphingosine 1-beta-galactosyltransferase-like , 2-hydroxyacylsphingosine 1-beta-galactosyltransferase , UDP-galactose-ceramide galactosyltransferase 8A , UDP-glucuronosyltransferase 8 , ceramide UDP-galactosyltransferase , cerebroside synthase , UDP-galactose ceramide galactosyltransferase , UDP-galactose-ceramide galactosyltransferase , uridine diphosphate glycosyltransferase 8 , UDP-galactose-ceramide galactosyltransferase 8 , UDP galactosyltransferase 8 , UDP galactosyltransferase 8A

461446 Pan troglodytes
702979 Macaca mulatta
779534 Xenopus (Silurana) tropicalis
100076336 Ornithorhynchus anatinus
100396627 Callithrix jacchus
100465291 Ailuropoda melanoleuca
100551810 Anolis carolinensis
100607960 Nomascus leucogenys
22239 Mus musculus
7368 Homo sapiens
374033 Gallus gallus
487910 Canis lupus familiaris
281566 Bos taurus
50555 Rattus norvegicus
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