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URI1 encodes member of the prefoldin family of molecular chaperones. Additionally we are shipping URI1, Prefoldin-Like Chaperone Proteins (4) and many more products for this protein.
Showing 10 out of 32 products:
Cow (Bovine) Polyclonal URI1 Primary Antibody for WB - ABIN2784320
Djouder, Metzler, Schmidt, Wirbelauer, Gstaiger, Aebersold, Hess, Krek: S6K1-mediated disassembly of mitochondrial URI/PP1gamma complexes activates a negative feedback program that counters S6K1 survival signaling. in Molecular cell 2007
Human Polyclonal URI1 Primary Antibody for ELISA, WB - ABIN563755
Mita, Savas, Djouder, Yates, Ha, Ruoff, Schafler, Nwachukwu, Tanese, Cowan, Zavadil, Garabedian, Logan: Regulation of androgen receptor-mediated transcription by RPB5 binding protein URI/RMP. in Molecular and cellular biology 2011
RMP (show ABCA4 Antibodies) status in tumors may be a useful marker in estimating prognosis in patients with hepatocellular carcinoma and in assisting in the selection of patients who are likely to benefit from adjuvant TACE (show ADAM17 Antibodies) to prevent relapse.
High URI1 (show C19orf2 Antibodies) expression is associated with epithelial ovarian cancer.
Results show that URI (show C19orf2 Antibodies) expression is essential for hepatocarcinogenesis and associated with poor survival.
URI (show C19orf2 Antibodies) may have an important role in the development of multiple myeloma and chemotherapeutic resistance through activation of the IL-6 (show IL6 Antibodies)/STAT3 (show STAT3 Antibodies) pathway.
Higher level of URI/RMP (show C19orf2 Antibodies) expression in high-grade endometrioid adenocarcinomas compared to tissues of adjacent endometrium or gland suggests a diagnostic and possibly, a prognostic value of URI/RMP (show C19orf2 Antibodies) in endometrioid adenocarcinoma.
Data show that while Art-27 (show UXT Antibodies) can bind AR directly, URI (show C19orf2 Antibodies) is bound to chromatin prior to hormone-dependent recruitment of AR, suggesting a role for URI (show C19orf2 Antibodies) in modulating AR recruitment to target genes.
Data show that URI (show C19orf2 Antibodies) is an "addicting" oncogene (show RAB1A Antibodies) selectively required for the survival of ovarian cancer cells with increased URI (show C19orf2 Antibodies) copy number.
Data show that URI (show C19orf2 Antibodies) and PP1gamma are components of an S6K1 (show RPS6KB1 Antibodies)-regulated mitochondrial pathway dedicated to oppose sustained S6K1 (show RPS6KB1 Antibodies) survival signaling and to ensure that the threshold for apoptosis is set based on nutrient and growth factor availability.
Is part of an RNA polymerase II-associated complex with possible chaperone activity.
This gene encodes member of the prefoldin family of molecular chaperones. The encoded protein functions as a scaffolding protein and plays roles in ubiquitination and transcription, in part though interactions with the RNA polymerase II subunit RPB5. This gene may play a role in multiple malignancies including ovarian cancer and hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 22.
RNA polymerase II subunit 5-mediating protein
, RPB5-mediating protein
, protein phosphatase 1 regulatory subunit 19
, protein phosphatase 1, regulatory subunit 19
, unconventional prefoldin RPB5 interactor 1