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The protein encoded by USO1 is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. Additionally we are shipping USO1 Homolog, Vesicle Docking Protein Antibodies (92) and USO1 Homolog, Vesicle Docking Protein Proteins (3) and many more products for this protein.
USO1 deficiency results in Golgi disruption and early embryonic lethality in mice.
The p115 (show ARHGAP4 ELISA Kits) structures show a novel alpha-solenoid architecture constructed of 12 armadillo (show PKP1 ELISA Kits)-like, tether-repeat, alpha-helical tripod motifs.
USO1 gene may be a promising target for the therapy of human multiple myeloma and its diagnosis marker.
USO1 gene has a critical role in human colon cancer: USO1 is involved in cell proliferation and cell migration of colon cancer cells.
P115 (show ARHGAP4 ELISA Kits) promotes proliferation of gastric cancer cells through an interaction with MIF (show AMH ELISA Kits).
Scyl1 (show CCL13 ELISA Kits) interacts with 58K/formiminotransferase cyclodeaminase (FTCD (show FTCD ELISA Kits)) and golgin p115 (show ARHGAP4 ELISA Kits), and is required for the maintenance of Golgi morphology.
p115 (show ARHGAP4 ELISA Kits) plays a critical role in mitosis progression, implicating it as the only known golgin to regulate both mitosis and apoptosis
a conserved tethering function of the Golgi protein (show GOLPH3 ELISA Kits) p115 (show ARHGAP4 ELISA Kits) CTF (show NFIA ELISA Kits) which promotes p53 (show TP53 ELISA Kits)-ERK (show EPHB2 ELISA Kits) interaction for the amplification of the apoptotic signal.
Data show that p115 (show ARHGAP4 ELISA Kits) degradation plays a key role in amplifying the apoptotic response independently of Golgi fragmentation.
p115 (show ARHGAP4 ELISA Kits) acts directly, rather than via a tether, to catalyze trans-SNARE (show NAPA ELISA Kits) complex formation preceding membrane fusion.
The results suggest that p115 (show ARHGAP4 ELISA Kits) is involved in vesicular transport between endoplasmic reticulum and the Golgi, along with microtubule networks.
The interaction between p115 (show ARHGAP4 ELISA Kits) and Cog2 was found to be essential for Golgi ribbon reformation after the disruption of the ribbon by p115 (show ARHGAP4 ELISA Kits) KD or brefeldin A treatment and recovery by re-expression of p115 (show ARHGAP4 ELISA Kits) or drug wash out, respectively.
General vesicular transport factor required for intercisternal transport in the Golgi stack\; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity (By similarity).
USO1 vesicle docking protein homolog
, USO1 homolog, vesicle docking protein
, USO1 vesicle docking protein homolog (yeast)
, vesicle docking protein p115
, general vesicular transport factor p115
, protein USO1 homolog
, transcytosis associated protein p115
, transcytosis-associated protein
, vesicle docking protein, 115 kDa
, vesicle-docking protein
, membrane tethering protein p115
, vesicular transport factor p115
, transcytosis associated protein