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UQCRB encodes a subunit of the ubiquinol-cytochrome c oxidoreductase complex, which consists of one mitochondrial-encoded and 10 nuclear-encoded subunits. Additionally we are shipping Ubiquinol-Cytochrome C Reductase Binding Protein Antibodies (50) and Ubiquinol-Cytochrome C Reductase Binding Protein Proteins (16) and many more products for this protein.
Zebrafish angiogenesis is inhibited by UQCRB knockdown.
UQCRB gene mutation is associated with mitochondrial complex III deficiency in a Chinese family.
a UQCRB mutation promotes angiogenesis through the generation of mitochondrial reactive oxygen species
Mitochondrial UQCRB regulates VEGFR2 (show KDR ELISA Kits) signaling in endothelial cells.
Studies indicate that mitochondrial oxygen sensor ubiquinol-cytochrome c reductase binding protein (UQCRB) as a terpestacin-binding protein.
Two SNPs in the 3' untranslated region of UQCRB (complex III), rs7836698 and rs10504961, were associated with overall survival.
Terpestacin inhibits tumor angiogenesis by targeting UQCRB of mitochondrial complex III and suppressing hypoxia-induced reactive oxygen species production and cellular oxygen sensing
This gene encodes a subunit of the ubiquinol-cytochrome c oxidoreductase complex, which consists of one mitochondrial-encoded and 10 nuclear-encoded subunits. The protein encoded by this gene binds ubiquinone and participates in the transfer of electrons when ubiquinone is bound. This protein plays an important role in hypoxia-induced angiogenesis through mitochondrial reactive oxygen species-mediated signaling. Mutations in this gene are associated with mitochondrial complex III deficiency. Alternatively spliced transcript variants have been found for this gene. Related pseudogenes have been identified on chromosomes 1, 5 and X.
ubiquinol-cytochrome c reductase binding protein
, cytochrome b-c1 complex subunit 7
, ubiquinol-cytochrome c reductase binding protein-like
, OXPHOS complex III 14 kDa protein
, complex III subunit 7
, complex III subunit VII
, mitochondrial ubiquinone-binding protein
, ubiquinol-cytochrome c reductase complex 14 kDa protein
, ubiquinol-cytochrome c reductase, complex III subunit VI