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anti-Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A) Antibodies

UBASH3A encodes one of two family members belonging to the T-cell ubiquitin ligand (TULA) family. Additionally we are shipping Ubiquitin Associated and SH3 Domain Containing, A Proteins (6) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
UBASH3A 53347 P57075
UBASH3A 328795 Q3V3E1
UBASH3A 309666  
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Top anti-Ubiquitin Associated and SH3 Domain Containing, A Antibodies at antibodies-online.com

Showing 10 out of 78 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN190877 (2.5µg/ml) staining of paraffin embedded Human Spleen. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$507.83
Details
Mouse Rabbit Un-conjugated WB UBASH3A Antibody (Center)  western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the UBASH3A antibody detected the UBASH3A protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated EIA, IHC (p), WB AP32140PU-N STS2 / TULA antibody staining of paraffin embedded Human Breast at 3.8 µg/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. AP32140PU-N STS2 / TULA antibody staining of Human Spleen lysate at 1 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated IHC, ELISA 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated IHC (p), ELISA Human Spleen (formalin-fixed, paraffin-embedded) stained with UBASH3A antibody ABIN290205 at 2.5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Goat Un-conjugated IHC (p), ELISA, WB 50 μg Log in to see 8 to 10 Days
$451.00
Details

UBASH3A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine) ,
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Top referenced anti-Ubiquitin Associated and SH3 Domain Containing, A Antibodies

  1. Human Polyclonal UBASH3A Primary Antibody for ELISA, WB - ABIN1451691 : Feshchenko, Smirnova, Swaminathan, Teckchandani, Agrawal, Band, Zhang, Annan, Carr, Tsygankov: TULA: an SH3- and UBA-containing protein that binds to c-Cbl and ubiquitin. in Oncogene 2004 (PubMed)
    Show all 2 references for ABIN1451691

  2. Cow (Bovine) Polyclonal UBASH3A Primary Antibody for WB - ABIN2782357 : Smirnova, Collingwood, Bisbal, Tsygankova, Bogush, Meinkoth, Henderson, Annan, Tsygankov: TULA proteins bind to ABCE-1, a host factor of HIV-1 assembly, and inhibit HIV-1 biogenesis in a UBA-dependent fashion. in Virology 2008 (PubMed)

  3. Human Polyclonal UBASH3A Primary Antibody for IHC, ELISA - ABIN190877 : Kowanetz, Crosetto, Haglund, Schmidt, Heldin, Dikic: Suppressors of T-cell receptor signaling Sts-1 and Sts-2 bind to Cbl and inhibit endocytosis of receptor tyrosine kinases. in The Journal of biological chemistry 2004 (PubMed)

More Antibodies against Ubiquitin Associated and SH3 Domain Containing, A Interaction Partners

Human Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A) interaction partners

  1. A negative correlation was found between UBASH3A mRNA expression and systemic lupus erythematosus.

  2. Findings suggest that UBASH3A gene might contribute to systemic lupus erythematosus susceptibility and influence the clinical phenotype of the disease.

  3. Addition of PTPN22 (show PTPN22 Antibodies) and UBASH3A SNPs to HLA-DR,DQ genotyping can improve type 1 diabetes risk prediction.

  4. Results suggest that UBASH3a gene plays a role in the susceptibility to systemic lupus erythematosus and UBASH3a can be considered as a common genetic factor in autoimmune diseases.

  5. ubiquitin associated and SH3 domain containing A appears to be an independent predictor of islet autoimmunity and type 1 diabetes in children, including those free of family history of T1D but carrying the HLA-DR3/4,DQB1*0302 genotype

  6. The UBASH3A promoter is activated by serum depletion according to promoter reporter assays in HEK (show EPHA3 Antibodies) 293 cells.

  7. Sts-1 (show STS1 Antibodies) and Sts-2 bind to Cbl (show CBL Antibodies) and inhibit endocytosis of receptor tyrosine kinases

  8. TULA inhibits both clathrin-dependent and clathrin-independent endocytic pathways by functionally sequestering dynamin (show DNM1 Antibodies) via the SH3 domain (show ITSN1 Antibodies) of TULA binding proline-rich sequences in dynamin (show DNM1 Antibodies)

  9. TULA enhances the apoptotic effect of AIF (show AIFM1 Antibodies) by facilitating the interactions of AIF (show AIFM1 Antibodies) with its apoptotic co-factors

  10. Binds to ABCE-1 (show ABCE1 Antibodies) and inhibits HIV-1 life cycle, most likely by disrupting essential ubiquitylation-dependent events.

Mouse (Murine) Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A) interaction partners

  1. Biochemical analysis identified STS-1 (show STS1 Antibodies) and STS-2 as direct phosphatases of FLT3 (show FLT3 Antibodies) and c-KIT (show KIT Antibodies).

  2. The lack of TULA facilitates T-cell responses to TCR/CD3 (show CD3E Antibodies) stimulation, thus exacerbating T-cell-dependent inflammation.

  3. Skeletal analysis of mice that do not express TULA or TULA-2 (show STS1 Antibodies) proteins (DKO mice) revealed that there was a decrease in bone volume due to increased osteoclast numbers and function.

  4. Sts-2 is a phosphatase that negatively regulates zeta-associated protein (ZAP)-70 (show ZAP70 Antibodies) and T cell receptor signaling pathways.

  5. Sts-2(phosphoglycerate mutase) adopts the conformation of an active phosphatase whose activity is fundamentally different from that of Sts-1 (show STS1 Antibodies) despite the strong structural homology.

  6. the crystal structure of Sts-2(PGM (show Vcan Antibodies)) in the phosphorylated active form and bound to VO(3)

  7. The Sts-1,2 proteins target tyrosine phosphorylated, ubiquitinated proteins within TCR signaling pathways.

Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A) Antigen Profile

Protein Summary

This gene encodes one of two family members belonging to the T-cell ubiquitin ligand (TULA) family. Both family members can negatively regulate T-cell signaling. This family member can facilitate growth factor withdrawal-induced apoptosis in T cells, which may occur via its interaction with AIF, an apoptosis-inducing factor. Alternative splicing of this gene results in multiple transcript variants.

Gene names and symbols associated with UBASH3A

  • ubiquitin associated and SH3 domain containing, A (UBASH3A) antibody
  • ubiquitin associated and SH3 domain containing A (UBASH3A) antibody
  • ubiquitin associated and SH3 domain containing, A (Ubash3a) antibody
  • 5830413C03Rik antibody
  • C330001M22 antibody
  • CLIP4 antibody
  • Sts-2 antibody
  • TULA antibody
  • TULA-1 antibody
  • UBASH3A antibody

Protein level used designations for UBASH3A

ubiquitin associated and SH3 domain containing, A , T-cell ubiquitin ligand 1 , T-cell ubiquitin ligand protein , cbl-interacting protein 4 , suppressor of T-cell receptor signaling 2 , ubiquitin-associated and SH3 domain-containing protein A

GENE ID SPECIES
418535 Gallus gallus
474125 Pan troglodytes
53347 Homo sapiens
487779 Canis lupus familiaris
514555 Bos taurus
328795 Mus musculus
309666 Rattus norvegicus
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