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Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) ELISA Kits

The protein encoded by UCHL1 belongs to the peptidase C12 family. Additionally we are shipping UCHL1 Antibodies (522) and UCHL1 Proteins (40) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
UCHL1 22223 Q9R0P9
UCHL1 7345 P09936
UCHL1 29545 Q00981
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Top UCHL1 ELISA Kits at antibodies-online.com

Showing 8 out of 20 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.28 ng/mL 0.78-50 ng/mL 96 Tests Log in to see 9 to 11 Days
$757.89
Details
Rat 25 pg/mL 20.58-15000 pg/mL 96 Tests Log in to see 9 to 11 Days
$960.00
Details
Human 0.056ng/mL 0.156-10 ng/mL   96 Tests Log in to see 11 to 12 Days
$908.41
Details
Rat 25pg/mL 78.125-5000 pg/mL   96 Tests Log in to see 11 to 12 Days
$973.11
Details
Mouse 0.31-20 ng/mL   1 kit Log in to see 9 Days
$891.43
Details
Pig
15.6-1000 pg/mL   96 Tests Log in to see 11 to 13 Days
$1,029.60
Details
Cow
  96 Tests Log in to see 11 to 13 Days
$1,029.60
Details
Rat
20.58-15000 pg/mL   96 Tests Log in to see 9 to 19 Days
$1,266.72
Details

Top referenced UCHL1 ELISA Kits

  1. Human UCHL1 ELISA Kit for Sandwich ELISA - ABIN422553 : Dobson, Topping, Davis, Thompson, Giovannoni: Cerebrospinal fluid and urinary biomarkers in multiple sclerosis. in Acta neurologica Scandinavica 2014 (PubMed)
    Show all 3 references for ABIN422553

More ELISA Kits for UCHL1 Interaction Partners

Mouse (Murine) Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) interaction partners

  1. The neuronal marker UCH-L1 is induced in, and specifically augments the oncogene (show RAB1A ELISA Kits)-induced transformation of, germinal center B cells.

  2. Pharmacological inhibition of UCHL1 exacerbates rather than ameliorates disease symptoms in a mouse model of SMA (show SMN1 ELISA Kits). Thus, pharmacological inhibition of UCHL1 is not a viable therapeutic target for SMA (show SMN1 ELISA Kits).

  3. Parkin (show PARK2 ELISA Kits) mediates K63-linked polyubiquitination of UCH-L1 in cooperation with the Ubc13 (show UBE2N ELISA Kits)/Uev1a E2 ubiquitin-conjugating enzyme (show UBE2L6 ELISA Kits) complex and promotes UCH-L1 degradation by the autophagy-lysosome pathway.

  4. defective UCHL1 function may be an early contributor to vulnerability of pancreatic beta-cells for protein misfolding and proteotoxicity, hallmark defects in islets of T2DM

  5. UCH-L1 facilitates PDGF (show PDGFA ELISA Kits)-BB-induced suppression of autophagic degradation of p21WAF1/Cip1 proteins in cardiac fibroblasts

  6. UCHL1 upregulation in ACTN4 (show ACTN4 ELISA Kits)-associated FSGS (show ACTN4 ELISA Kits).

  7. downregulated miR (show MLXIP ELISA Kits)-181b induces neuroprotection against ischemic injury through negatively regulating HSPA5 (show HSPA5 ELISA Kits) and UCHL1 protein levels

  8. The proteases HtrA2/Omi (show HTRA2 ELISA Kits) and UCH-L1 regulate TNF (show TNF ELISA Kits)-induced necroptosis.

  9. Activation of the NF-kappaB (show NFKB1 ELISA Kits) signaling pathway could be the major pathogenic mechanism to up-regulate UCH-L1 in podocyte injury.

  10. in AD, Abeta (show APP ELISA Kits) may down-regulate UCH-L1 in the AD brain, which in turn impairs BDNF (show BDNF ELISA Kits)/TrkB (show NTRK2 ELISA Kits)-mediated retrograde signaling, compromising synaptic plasticity and neuronal survival.

Human Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) interaction partners

  1. Folloing aneurysmal subarachnoid hemorrhage, eleevated UCH-L1 levels during the five-day follow-up were associated with unfavorable neurological outcome.

  2. UCH-L1 plays a crucial role in modulating the degradation of EGFR (show EGFR ELISA Kits) and promoting malignant properties in multi-drug resistant breast cancer

  3. High UCHL1 expression is associated with multiple myeloma.

  4. The neuronal marker UCH-L1 is induced in, and specifically augments the oncogene (show RAB1A ELISA Kits)-induced transformation of, germinal center B cells.

  5. The promoter methylation degree of FLNC (show FLNC ELISA Kits), THBS1 (show THBS1 ELISA Kits), UCHL1, and DLEC1 (show DLEC1 ELISA Kits) in serum could tell the existence of GC and only UCHL1 in the serum was also associated with poor prognosis of GC.

  6. The results of this study suggest the role for UCHL1 in promoting Corticospinal motor neurons health and stability.

  7. UCH-L1 is significantly associated with outcome, but it does not add predictive power to commonly used prognostic variables in a population of patients with TBI of varying severities.

  8. Serum UCH-l1 levels serve as a novel biomarker for neuronal damage from white matter lesions.

  9. High Ubiquitin C-terminal hydrolase-L1 increases cancer cell invasion by modulating hydrogen peroxide generated via NADPH oxidase 4 (show NOX4 ELISA Kits).

  10. These findings demonstrated that UCHL1 promoted cell proliferation, migration, and invasion depending on its de-ubiquitinase activity by activating Akt (show AKT1 ELISA Kits) and Erk1/2 (show MAPK1/3 ELISA Kits) pathways

Cow (Bovine) Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) interaction partners

  1. These data indicate that antipolyspermy defense in bovine oocytes may rely on UCHL1-controlled functioning of These data indicate that antipolyspermy defense in bovine oocytes may rely on UCHL1-controlled functioning of cortical granules.

Pig (Porcine) Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) interaction partners

  1. The elevation in UCH-L1 concentration is consistent with the severity of neural apoptosis following DHCA.

  2. Data report that ubiquitin carboxy-terminal hydrolase 1 is expressed in spermatogonia located at the basement membrane of seminiferous tubules at high and low levels, but not in differentiated germ cells distant from the BM.

Horse (Equine) Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) interaction partners

  1. There was no difference in enteric neuronal density and distribution in the groups of animals with intestinal disease compared with those without, apart from two (out of 28) horses with intestinal disease that showed reduction in PGP 9.5 immunoreactivity.

UCHL1 Antigen Profile

Antigen Summary

The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.

Gene names and symbols associated with UCHL1

  • ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (uchl1) antibody
  • ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (UCHL1) antibody
  • Ubiquitin carboxyl-terminal hydrolase isozyme L1 (uchl1) antibody
  • ubiquitin carboxyl-terminal esterase L1 (LOC100304750) antibody
  • ubiquitin carboxyl-terminal esterase L1 (LOC100348287) antibody
  • ubiquitin carboxyl-terminal esterase L1 (LOC100357806) antibody
  • ubiquitin carboxy-terminal hydrolase L1 (Uchl1) antibody
  • ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (Uchl1) antibody
  • AW822034 antibody
  • C88048 antibody
  • cb358 antibody
  • gad antibody
  • MGC132191 antibody
  • PARK5 antibody
  • PGP9.5 antibody
  • PGP 9.5 antibody
  • PGP95 antibody
  • R75593 antibody
  • Uch-L1 antibody
  • UCHL-1 antibody
  • uchl1 antibody
  • wu:fc55h08 antibody

Protein level used designations for UCHL1

ubiquitin carboxyl-terminal hydrolase isozyme L1 , ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) , ubiquitin carboxyl-terminal esterase L1 , gracile axonal dystrophy , neuron cytoplasmic protein 9.5 , protein gene product 9.5 , ubiquitin thioesterase L1 , ubiquitin C-terminal hydrolase , PGP 9.5 , PGP9.5 , UCH-L1 , ubiquitin carboxy-terminal hydrolase L1 , ubiquitin C-terminal hydrolase-L1 , ubiquitin carboxyl-terminal hydrolase L1 , ubiquitin thiolesterase L1

GENE ID SPECIES
325119 Danio rerio
461185 Pan troglodytes
479098 Canis lupus familiaris
751589 Taeniopygia guttata
770302 Gallus gallus
496780 Xenopus (Silurana) tropicalis
735204 Xenopus laevis
100196868 Salmo salar
100304750 Ictalurus punctatus
100348287 Oryctolagus cuniculus
100357806 Oryctolagus cuniculus
22223 Mus musculus
7345 Homo sapiens
29545 Rattus norvegicus
514394 Bos taurus
100714582 Cavia porcellus
396637 Sus scrofa
100033838 Equus caballus
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