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Ubiquitin Conjugation Factor E4 B (UBE4B) ELISA Kits

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Additionally we are shipping UBE4B Antibodies (43) and UBE4B Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat UBE4B UBE4B 298652  
Anti-Human UBE4B UBE4B 10277 O95155
Anti-Mouse UBE4B UBE4B 63958 Q9ES00
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More ELISA Kits for UBE4B Interaction Partners

Human Ubiquitin Conjugation Factor E4 B (UBE4B) interaction partners

  1. UBE4B overexpression promotes the oncogenic properties of HCC (show FAM126A ELISA Kits) and is correlated with an unfavorable prognosis in HCC (show FAM126A ELISA Kits) patients.

  2. UBE4B regulates p53 (show TP53 ELISA Kits) in breast cancer

  3. We propose a model in which the coordinated action of UBE4B, ESCRT-0, and the deubiquitinating enzyme USP8 (show USP8 ELISA Kits) enable the endosomal sorting and lysosomal degradation of the EGFR (show EGFR ELISA Kits).

  4. UBE4B-mediated growth factor receptor (show RYK ELISA Kits) trafficking may contribute to the poor prognosis of patients who have neuroblastoma (show ARHGEF16 ELISA Kits) tumors with 1p36 deletions.

  5. The regulated expression of these UFD2a isoforms most likely imparts divergent functions that are important for myogenesis.

  6. we found somatic mutations of HERC2 (show HERC2 ELISA Kits), HERC3, TRIP12, UBE2Q1 (show UBE2Q1 ELISA Kits) and UBE4B genes in gastric carcinoma and colorectal carcinomas with microsatellite instability

  7. data indicate that amplification and overexpression of UBE4B represent previously undescribed molecular mechanisms of inactivation of p53 (show TP53 ELISA Kits) in brain tumors

  8. determined structures of E4B U box free and bound to UbcH5c (show UBE2D3 ELISA Kits) and Ubc4 (show UBE2D2 ELISA Kits) E2s; findings show E4B U box is a monomer stabilized by a network of hydrogen bonds; findings suggest allosteric regulation of UbcH5c (show UBE2D3 ELISA Kits) and Ubc4 (show UBE2D2 ELISA Kits) by E4B U box

  9. A splice site mutation was found in UBE4b. UBE4B expression was diminished in the high-stage/poor-outcome tumors.UBE4B stands out as the strongest candidate NBL (show NUMBL ELISA Kits) tumor suppressor gene in the region at this stage.

  10. E4B serves as a ubiquitin ligase for FEZ1 (show LZTS1 ELISA Kits) and thereby regulates its function but not its degradation

Mouse (Murine) Ubiquitin Conjugation Factor E4 B (UBE4B) interaction partners

  1. The regulated expression of these UFD2a isoforms most likely imparts divergent functions that are important for myogenesis.

  2. Characterization of the UFD2a gene.

  3. UFD2a is essential for the development of cardiac muscle, as well as for the protection of spinocerebellar neurons from degeneration induced by endoplasmic reticulum stress.

UBE4B Antigen Profile

Antigen Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene names and symbols associated with UBE4B

  • ubiquitination factor E4B (Ube4b) antibody
  • ubiquitin conjugation factor E4 B (LinJ30.1380) antibody
  • ubiquitin conjugation factor E4 B (LbrM30_V2.1130) antibody
  • ubiquitin conjugation factor E4 B (Tsp_12732) antibody
  • ubiquitin conjugation factor E4 B (Tsp_01624) antibody
  • ubiquitination factor E4B, UFD2 homolog (S. cerevisiae) (ube4b) antibody
  • ubiquitination factor E4B (UBE4B) antibody
  • ubiquitination factor E4B, UFD2 homolog (S. cerevisiae) (Ube4b) antibody
  • 4930551I19Rik antibody
  • 4933406G05Rik antibody
  • AU014668 antibody
  • D4Bwg0973e antibody
  • E4 antibody
  • HDNB1 antibody
  • mKIAA0684 antibody
  • UBOX3 antibody
  • UFD2 antibody
  • UFD2a antibody
  • Ufd2p antibody

Protein level used designations for UBE4B

ubiquitin conjugation factor E4 B , ubiquitination factor E4B (UFD2 homolog, yeast) , ubiquitination factor E4B, UFD2 homolog , ubiquitin fusion degradation protein 2 , UFD2A-III/UBE4B-III splice isoform , homologous to yeast UFD2 , homozygously deleted in neuroblastoma 1 , homozygously deleted in neuroblastoma-1 , ubiquitin-fusion degradation protein 2 , ubiquitination factor E4B (homologous to yeast UFD2)

GENE ID SPECIES
298652 Rattus norvegicus
5070994 Leishmania infantum JPCM5
5417638 Leishmania braziliensis MHOM/BR/75/M2904
10899986 Trichinella spiralis
10911805 Trichinella spiralis
100380420 Salmo salar
10277 Homo sapiens
63958 Mus musculus
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