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human homolog is a diubiquitin protein that may function in antigen processing and presentation [RGD, Feb 2006].. Additionally we are shipping UBD Proteins (16) and UBD Kits (12) and many more products for this protein.
Showing 10 out of 71 products:
Human Polyclonal UBD Primary Antibody for EIA, IF - ABIN952269
Gong, Canaan, Wang, Leventhal, Snyder, Nair, Cohen, Kretzler, DAgati, Weissman, Ross: The ubiquitin-like protein FAT10 mediates NF-kappaB activation. in Journal of the American Society of Nephrology : JASN 2010
Show all 3 references for ABIN952269
Mouse (Murine) Polyclonal UBD Primary Antibody for IF, IHC (p) - ABIN655263
Ucisik-Akkaya, Davis, Do, Morrison, Stemmer, Amadio, Dorak: Examination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection. in Molecular human reproduction 2010
Show all 2 references for ABIN655263
Cow (Bovine) Polyclonal UBD Primary Antibody for WB - ABIN2782518
Burfoot, Jensen, Field, Stankovich, Varney, Johnson, Butzkueven, Booth, Bahlo, Tait, Taylor, Speed, Heard, Stewart, Foote, Kilpatrick, Rubio: SNP mapping and candidate gene sequencing in the class I region of the HLA complex: searching for multiple sclerosis susceptibility genes in Tasmanians. in Tissue antigens 2007
Human Polyclonal UBD Primary Antibody for IF, WB - ABIN523947
Sun, Liu, Yu, Li, Sun, Yang: Increased FAT10 expression is related to poor prognosis in pancreatic ductal adenocarcinoma. in Tumour biology 2014
repertoire of peptides eluted from MHC class I molecules was influenced by FAT10 expression
FAT10 is the only ubiquitin-like modifier known to date which directly targets its hundreds of substrates for degradation by the proteasome. (Review)
Conjugation of the ubiquitin activating enzyme UBE1 (show UBA1 Antibodies) with the ubiquitin-like modifier FAT10 targets it for proteasomal degradation
the interaction of FAT10 with MAD2 (show MAD2L1 Antibodies) is a key mechanism underlying the promalignant property of FAT10
Results identified a novel HCC (show FAM126A Antibodies) regulatory circuit involving FAT10, beta-catenin (show CTNNB1 Antibodies)/TCF4 (show TCF4 Antibodies), and HOXB9 (show HOXB9 Antibodies), the dysfunction of which drives invasive and metastatic character in HCC (show FAM126A Antibodies).
STAT3 (show STAT3 Antibodies) and NFkappaB (show NFKB1 Antibodies) synergistically act for maximum induction of FAT10 expression.
transcription downregulation of the Ufm1 (show UFM1 Antibodies) and FAT10 conjugation system in liver Mallory-Denk bodies formation
functional distribution of the FAT10 targets suggests that FAT10 participates in various biological processes, such as translation, protein folding, RNA processing, and macromolecular complex assembly
FAT10 expression in pancreatic ductal adenocarcinoma (PDAC) was an independent prognostic factor of patients, which might be a potential diagnostic and therapeutic target of PDAC
These results suggest that knockdown of FAT10 by adenovirus-delivered siRNA may be a promising therapeutical strategy for treatment of hepatocellular carcinoma.
IFNalpha induced FAT10 expression, which is suppressed by ethanol feeding in both HCV(+) and HCV(-) mice
observations suggest novel roles of FAT10 in immune metabolic regulation that impact aging and chronic disease
FAT10 protects cardiac myocytes against apoptosis.
FAT10 is essential to the induction of Mallory-Denk body formation in di-carbethoxydihydrocollidine fed mice.
FAT10 mediates NF-kappaB (show NFKB1 Antibodies) activation and may promote tubulointerstitial inflammation in chronic kidney diseases.
Immunohistochemical studies demonstrated increased FAT10 expression in a model of HIV-associated nephropathy.
These findings indicate that FAT10 may function as a survival factor.
The link between Mallory Denk Body formation and neoplasia formation was likely due to the over expression of UBD (also called FAT10), which is up regulated in 90% of human hepatocellular carcinomas.
human homolog is a diubiquitin protein that may function in antigen processing and presentation
, ubiquitin-like protein FAT10