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Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) ELISA Kits

UBR5 encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. Additionally we are shipping UBR5 Antibodies (76) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
UBR5 51366 O95071
UBR5 70790 Q80TP3
Anti-Rat UBR5 UBR5 117060  
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More ELISA Kits for UBR5 Interaction Partners

Human Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) interaction partners

  1. Colony-formation assays and soft agar assays show that gain of function of TIP60 or depletion of EDD1 in HPV-positive cervical cancer cells significantly inhibits cell growth in vitro

  2. Human herpesvirus-6 U14 induces cell cycle arrest in G2/M phase by associating with a cellular protein, EDD.

  3. Elevated metaphase RanGTP levels use Ubr5 to couple overall chromosome congression to SAC (show ADCY10 ELISA Kits) silencing.

  4. results confirm the role of the MLLE domain of UBR5 in substrate recruitment and suggest a potential role in regulating UBR5 ligase activity.

  5. these observations highlight the potential role of EDD in regulating mitotic progression and the cellular response to perturbed mitosis.

  6. Utilizing a high throughput RNAi screening approach author identified UBR5, a protein commonly amplified in breast cancer, as a novel regulator of ERalpha (show ESR1 ELISA Kits) protein levels and transcriptional activity.

  7. the alpha4 N-terminus binding to endogenous PP2Ac and PABP (show PABPC1 ELISA Kits), and the C-terminus to EDD, is reported.

  8. These results identify EDD as a dual regulator of cell survival and cisplatin resistance and suggest that EDD is a therapeutic target for ovarian cancer.

  9. Determined is the three-dimensional solution structure of the catalytic RING2 (show RNF2 ELISA Kits) domain from HHARI (show ARIH1 ELISA Kits). It shows glimpses of a HECT E3 ligase.

  10. UBR5 knockdown results in accumulation of cellular pregnane X receptor (show NR1I2 ELISA Kits) and an increase in its activity.

Mouse (Murine) Ubiquitin Protein Ligase E3 Component N-Recognin 5 (UBR5) interaction partners

  1. UBR5-mediated ATMIN ubiquitination is a vital event for ATM (show ATM ELISA Kits) pathway selection and activation in response to DNA damage

  2. a novel function of RIP1 (show RALBP1 ELISA Kits) kinase involving its interaction with EDD to regulate JNK (show MAPK8 ELISA Kits) activation and TNFalpha (show TNF ELISA Kits) production.

  3. Silencing Edd1 with shRNA in mouse embryonic stem cells significantly suppressed their growth.

  4. The SCF (show KITLG ELISA Kits) E3 ligase complex containing Fbxo40 (show FBXO40 ELISA Kits) directly ubiquitinates IRS1 (show IRS1 ELISA Kits), and this activity is enhanced by increased tyrosine phosphorylation of IRS1 (show IRS1 ELISA Kits).

  5. Through the PABC domain, EDD participates in miRNA silencing by recruiting downstream effectors.

  6. UBR5 can attenuate myocardin (show MYOCD ELISA Kits) protein degradation resulting in increased myocardin (show MYOCD ELISA Kits) protein expression without affecting myocardin (show MYOCD ELISA Kits) mRNA expression.

  7. Results suggest that Edd has an essential role in extraembryonic development.

UBR5 Antigen Profile

Antigen Summary

This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation.

Gene names and symbols associated with UBR5

  • ubiquitin protein ligase E3 component n-recognin 5 (UBR5) antibody
  • ubiquitin protein ligase E3 component n-recognin 5 (Ubr5) antibody
  • 4432411E13Rik antibody
  • AW549941 antibody
  • C77315 antibody
  • D030042K14 antibody
  • Dd5 antibody
  • Edd antibody
  • Edd1 antibody
  • HYD antibody
  • mKIAA0896 antibody
  • Rat100 antibody

Protein level used designations for UBR5

E3 identified by differential display , E3 ubiquitin protein ligase, HECT domain containing, 1 , E3 ubiquitin-protein ligase UBR5 , E3 ubiquitin-protein ligase, HECT domain-containing 1 , hHYD , hyperplastic discs protein homolog , progestin induced protein , progestin-induced protein , ubiquitin-protein ligase , extraembryonic development

51366 Homo sapiens
70790 Mus musculus
117060 Rattus norvegicus
420252 Gallus gallus
475055 Canis lupus familiaris
100157625 Sus scrofa
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