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Ubiquitin Protein Ligase E3C Proteins (UBE3C)

E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Additionally we are shipping UBE3C Antibodies (23) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat UBE3C UBE3C 362294  
UBE3C 9690 Q15386
Mouse UBE3C UBE3C 100763 Q80U95
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Top UBE3C Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

UBE3C Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for Ubiquitin Protein Ligase E3C (UBE3C) Interaction Partners

Human Ubiquitin Protein Ligase E3C (UBE3C) interaction partners

  1. data reveal that high UBE3C expression contributes to glioma progression by ubiquitination and degradation of ANXA7 (show ANXA7 Proteins), and thus presents a novel and promising target for glioma therapy.

  2. these observations suggest that UBE3C plays an important role in RCC (show XRCC1 Proteins) development and progression, and UBE3C may be a novel target for prevention and treatment of ccRCC.

  3. UBE3C is a mutant candidate oncogene (show RAB1A Proteins) involved in tumor development and progression of hepatocellular carcinoma.

  4. knockdown renders cells more susceptible to the Hsp90 (show HSP90 Proteins) inhibitor 17-AAG (show MPG Proteins), suggesting that UBE3C protects against the harmful accumulation of protein fragments arising from incompletely degraded proteasome substrates.

  5. Our findings provide evidence that variations in UBE3C are potent genetic markers of nasal polyps development in Korean asthmatics.

  6. negatively regulates type I interferon (show IFNA Proteins) through ubiquitination of the transcription factors

  7. TIP120B (show CAND2 Proteins) is a specific substrate of KIAA10; both are highly expressed in human skeletal muscle, suggesting that KIAA10 may regulate TIP120B (show CAND2 Proteins) homeostasis specifically in this tissue.

UBE3C Protein Profile

Protein Summary

E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.

Gene names and symbols associated with UBE3C

  • ubiquitin protein ligase E3C (Ube3c)
  • ubiquitin protein ligase E3C (ube3c)
  • ubiquitin protein ligase E3C (UBE3C)
  • ubiquitin protein ligase E3C (LOC100228118)
  • AI853514 protein
  • HECTH2 protein
  • kiaa0010 protein
  • MGC146390 protein
  • mKIAA0010 protein
  • RGD1559986 protein
  • UBE3C protein
  • zgc:63649 protein

Protein level used designations for UBE3C

ubiquitin-protein ligase E3C , ubiquitin protein ligase E3C , ubiquitin-protein isopeptide ligase (E3) , ubiquitin-protein ligase E3C-like

GENE ID SPECIES
362294 Rattus norvegicus
393445 Danio rerio
420447 Gallus gallus
472637 Pan troglodytes
482822 Canis lupus familiaris
508513 Bos taurus
719956 Macaca mulatta
380493 Xenopus laevis
779973 Xenopus (Silurana) tropicalis
100016776 Monodelphis domestica
100228118 Taeniopygia guttata
100475169 Ailuropoda melanoleuca
100547787 Meleagris gallopavo
9690 Homo sapiens
100763 Mus musculus
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