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anti-Ubiquitin Specific Peptidase 1 (USP1) Antibodies

USP1 encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. Additionally we are shipping USP1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
USP1 7398 O94782
USP1 230484 Q8BJQ2
USP1 313387 Q569C3
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Top anti-USP1 Antibodies at antibodies-online.com

Showing 10 out of 87 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-USP1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human brain WB Suggested Anti-USP1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Human brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB USP1 Antibody (C-term)  western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the USP1 antibody detected the USP1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-USP1 Pab (ABIN388876) in HepG2 cell line lysate (35 µg/lane). USP1(arrow) was detected using the purified polyclonal antibody (1:60 dilution) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and human liver tissue labeled with Anti-USP-1 Polyclonal Antibody, Unconjugated (ABIN675578) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and human glioma tissue labeled with Anti-USP-1 Polyclonal Antibody, Unconjugated (ABIN675578) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μg Log in to see 2 to 3 Days
$378.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Mouse Rabbit Un-conjugated IHC, WB 200 μL Log in to see 9 Days
$588.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

USP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-USP1 Antibodies

  1. Human Polyclonal USP1 Primary Antibody for EIA, IHC (p) - ABIN357518 : Fujiwara, Saito, Suzuki, Shinomiya, Suzuki, Takahashi, Tanigami, Ichiyama, Chung, Nakamura, Tanaka: Identification and chromosomal assignment of USP1, a novel gene encoding a human ubiquitin-specific protease. in Genomics 1999 (PubMed)
    Show all 2 references for ABIN357518

More Antibodies against USP1 Interaction Partners

Human Ubiquitin Specific Peptidase 1 (USP1) interaction partners

  1. Translational regulation of the mRNA encoding USP1 is involved in the DNA damage response as a determinant of cisplatin resistance.

  2. Ubiquitination-specific proteases 1 (USP1)-mediated protein stabilization promotes glioblastoma (GBM) stem-like cells maintenance and treatment resistance, thereby providing a rationale for USP1 inhibition as a potential therapeutic approach against GBM.

  3. analysis of the function and regulation of the USP1-UAF1 (show WDR48 Antibodies) complex

  4. USP1, p21 and Spartan are translesion DNA synthesis regulators. (Review)

  5. No correlation was observed between the protein level of ubiquitin-specific protease 1 (USP1) and ubiquitinated PCNA (show PCNA Antibodies) in BAF180 (show PBRM1 Antibodies) expressing cells

  6. USP1 phosphorylation at S313 is not critical for PCNA (show PCNA Antibodies) deubiquitination, neither for binding to UAF1 (show WDR48 Antibodies) in a cellular environment.

  7. Coimmunoprecipitation experiments indicated that human papillomavirus type 31 E1 assembles into a ternary complex with UAF1 (show WDR48 Antibodies) and any one of these three USPs: USP1, USP12 (show USP12 Antibodies) and USP46 (show USP46 Antibodies).

  8. Our findings revealed an intriguing mechanism of regulating USP1 activity that combines phosphorylation of a key serine residue in USP1 and the specific interaction of USP1 with a WD40-repeat protein UAF1

  9. USP1 and UAF1 (show WDR48 Antibodies) form a complex in the cytoplasm that subsequently translocates to the nucleus through import mediated by USP1 nuclear localization signals.

  10. data identified a novel USP1-PHLPP1 (show PHLPP1 Antibodies)-Akt (show AKT1 Antibodies) signaling axis, and decreased USP1 level in lung cancer cells may play an important role in lung cancer progress.

Mouse (Murine) Ubiquitin Specific Peptidase 1 (USP1) interaction partners

  1. Data suggest Usp1 down-regulation by autocleavage is critical for Usp1 to exert role in DNA interstrand crosslink repair; Usp1 role is de-ubiquitination of Fancd2 (Fanconi anemia complementation group D2 (show FANCD2 Antibodies)) and Pcna (proliferating cell nuclear antigen (show PCNA Antibodies)).

  2. Homozygous Uaf1 (show WDR48 Antibodies)(-/-) embryos died at embryonic day 7.5 (E7.5). These mutant embryos were small and developmentally retarded.

  3. Autocleaved Usp1 remains a deubiquitylase because its fragments remain associated with Uaf1, an enhancer of Usp1 activity, until the C-terminal fragment is selectively destroyed by the Arg/N-end rule pathway.

  4. Bone marrow from Fancd2 (show FANCD2 Antibodies)-/- mice and Usp1-/- mice exhibited marked hematopoietic defects.

  5. mouse Usp1 functions downstream in the Fanconi anemia (show PALB2 Antibodies) pathway, and its deubiquitination is required for Fancd2 (show FANCD2 Antibodies) nuclear foci assembly

USP1 Antigen Profile

Protein Summary

This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized.

Gene names and symbols associated with USP1

  • ubiquitin specific peptidase 1 (USP1) antibody
  • ubiquitin specific peptidase 1 (usp1) antibody
  • ubiquitin specific peptidase 1 (Usp1) antibody
  • UBP antibody
  • usp1-a antibody

Protein level used designations for USP1

ubiquitin carboxyl-terminal hydrolase 1 , ubiquitin specific protease 1 , ubiquitin specific peptidase 1 , ubiquitin carboxyl-terminal hydrolase 1-like , deubiquitinating enzyme 1 , hUBP , ubiquitin carboxyl terminal hydrolase 1 , ubiquitin specific processing protease 1 , ubiquitin thioesterase 1 , ubiquitin thiolesterase 1 , ubiquitin-specific-processing protease 1 , ubiquitin specific peptdiase 1

GENE ID SPECIES
100070397 Equus caballus
447465 Xenopus laevis
456901 Pan troglodytes
695157 Macaca mulatta
100443075 Pongo abelii
7398 Homo sapiens
230484 Mus musculus
313387 Rattus norvegicus
424685 Gallus gallus
479549 Canis lupus familiaris
100523071 Sus scrofa
516328 Bos taurus
Selected quality suppliers for anti-USP1 (USP1) Antibodies
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