Ubiquitin Specific Peptidase 1 (USP1) ELISA Kits

USP1 encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. Additionally we are shipping USP1 Antibodies (95) and USP1 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human USP1 USP1 7398 O94782
Anti-Mouse USP1 USP1 230484 Q8BJQ2
Anti-Rat USP1 USP1 313387 Q569C3
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More ELISA Kits for USP1 Interaction Partners

Human Ubiquitin Specific Peptidase 1 (USP1) interaction partners

  1. USP1 is a key senescence regulator controlling genomic integrity.

  2. High USP1 expression is associated with glioma.

  3. USP1-UAF1 complex promotes homologous recombination repair via multiple mechanisms: through FANCD2 deubiquitination, as well as by interacting with RAD51AP1.

  4. The results suggest that silencing USP1 inhibits cell proliferation and invasion in U2OS cells. Therefore, USP1 may provide a novel therapeutic target for the treatment of osteosarcoma.

  5. Translational regulation of the mRNA encoding USP1 is involved in the DNA damage response as a determinant of cisplatin resistance.

  6. Ubiquitination-specific proteases 1 (USP1)-mediated protein stabilization promotes glioblastoma (GBM) stem-like cells maintenance and treatment resistance, thereby providing a rationale for USP1 inhibition as a potential therapeutic approach against GBM.

  7. analysis of the function and regulation of the USP1-UAF1 (show WDR48 ELISA Kits) complex

  8. USP1, p21 and Spartan are translesion DNA synthesis regulators. (Review)

  9. No correlation was observed between the protein level of ubiquitin-specific protease 1 (USP1) and ubiquitinated PCNA (show PCNA ELISA Kits) in BAF180 (show PBRM1 ELISA Kits) expressing cells

  10. USP1 phosphorylation at S313 is not critical for PCNA (show PCNA ELISA Kits) deubiquitination, neither for binding to UAF1 (show WDR48 ELISA Kits) in a cellular environment.

Mouse (Murine) Ubiquitin Specific Peptidase 1 (USP1) interaction partners

  1. our results strongly suggest that Usp1 is involved in the regulation of centrosome duplication, at least in part via ID1 (show ID1 ELISA Kits), and Usp1 may exert its oncogenic activity, partially through inducing centrosome abnormality.

  2. Data suggest Usp1 down-regulation by autocleavage is critical for Usp1 to exert role in DNA interstrand crosslink repair; Usp1 role is de-ubiquitination of Fancd2 (Fanconi anemia complementation group D2 (show FANCD2 ELISA Kits)) and Pcna (proliferating cell nuclear antigen (show PCNA ELISA Kits)).

  3. Homozygous Uaf1 (show WDR48 ELISA Kits)(-/-) embryos died at embryonic day 7.5 (E7.5). These mutant embryos were small and developmentally retarded.

  4. Autocleaved Usp1 remains a deubiquitylase because its fragments remain associated with Uaf1 (show WDR48 ELISA Kits), an enhancer of Usp1 activity, until the C-terminal fragment is selectively destroyed by the Arg/N-end rule pathway.

  5. Bone marrow from Fancd2 (show FANCD2 ELISA Kits)-/- mice and Usp1-/- mice exhibited marked hematopoietic defects.

  6. mouse Usp1 functions downstream in the Fanconi anemia (show PALB2 ELISA Kits) pathway, and its deubiquitination is required for Fancd2 (show FANCD2 ELISA Kits) nuclear foci assembly

USP1 Antigen Profile

Antigen Summary

This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized.

Gene names and symbols associated with USP1

  • ubiquitin specific peptidase 1 (USP1) antibody
  • ubiquitin specific peptidase 1 (usp1) antibody
  • ubiquitin specific peptidase 1 (Usp1) antibody
  • UBP antibody
  • usp1-a antibody

Protein level used designations for USP1

ubiquitin carboxyl-terminal hydrolase 1 , ubiquitin specific protease 1 , ubiquitin specific peptidase 1 , ubiquitin carboxyl-terminal hydrolase 1-like , deubiquitinating enzyme 1 , hUBP , ubiquitin carboxyl terminal hydrolase 1 , ubiquitin specific processing protease 1 , ubiquitin thioesterase 1 , ubiquitin thiolesterase 1 , ubiquitin-specific-processing protease 1 , ubiquitin specific peptdiase 1

100070397 Equus caballus
447465 Xenopus laevis
456901 Pan troglodytes
695157 Macaca mulatta
100443075 Pongo abelii
7398 Homo sapiens
230484 Mus musculus
313387 Rattus norvegicus
424685 Gallus gallus
479549 Canis lupus familiaris
100523071 Sus scrofa
516328 Bos taurus
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