Ubiquitin Specific Peptidase 12 (USP12) ELISA Kits

Deubiquitinating enzyme. Additionally we are shipping USP12 Antibodies (73) and USP12 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse USP12 USP12 22217 Q9D9M2
Anti-Rat USP12 USP12 360763  
Anti-Human USP12 USP12 219333 O75317
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More ELISA Kits for USP12 Interaction Partners

Mouse (Murine) Ubiquitin Specific Peptidase 12 (USP12) interaction partners

  1. Mechanistic analysis suggest that USP12 may be required for the activation of NFkappaB pathway as knockdown of USP12 reduced the inhibitory phosphorylation of IkappaBalpha, a well characterized inhibitor of NFkappaB nuclear translocation.

  2. Product has deubiquitinating enzyme activity and sequence analysis showed 98.3% amino acid identity with human UBH1.

Xenopus laevis Ubiquitin Specific Peptidase 12 (USP12) interaction partners

  1. we identified USP12 and USP46 as histone H2A and H2B deubiquitinases that regulate Xenopus development

Human Ubiquitin Specific Peptidase 12 (USP12) interaction partners

  1. UAF1 (show WDR48 ELISA Kits) and WDR20 (show WDR20 ELISA Kits) interact with USP12 at two distinct sites far from its catalytic center, allosterically activating the enzyme.

  2. Usp12 deubiquitylates and prevents lysosomal degradation of LAT and Trat1 to maintain the proximal TCR complex for the duration of signaling.

  3. Results suggest role for USP46 (show USP46 ELISA Kits)/USP12 in Epstein-Barr virus induced growth transformation.

  4. Usp12 directly deubiquitinates and stabilises the Akt (show AKT1 ELISA Kits) phosphatases PHLPP (show PHLPP1 ELISA Kits) and PHLPPL resulting in decreased levels of active pAkt (show AKT1 ELISA Kits).

  5. Coimmunoprecipitation experiments indicated that human papillomavirus type 31 E1 assembles into a ternary complex with UAF1 (show WDR48 ELISA Kits) and any one of these three USPs: USP1 (show USP1 ELISA Kits), USP12 and USP46 (show USP46 ELISA Kits).

  6. our results reveal WDR48 (show WDR48 ELISA Kits) and USP12 as novel PHLPP1 (show PHLPP1 ELISA Kits) regulators and potential suppressors of tumor cell survival

  7. Usp12 acts in a pro-proliferative manner by stabilizing AR and enhancing its cellular function.

  8. The ubiquitin-specific protease 12 (USP12) is a negative regulator of notch (show NOTCH1 ELISA Kits) signaling acting on notch (show NOTCH1 ELISA Kits) receptor trafficking toward degradation.

  9. WDR20 (show WDR20 ELISA Kits) serves as a stimulatory subunit for preserving and regulating the activity of the subset of the UAF1 (show WDR48 ELISA Kits) x USP12 complexes

  10. two novel multisubunit deubiquitinating enzyme complexes containing USP12 and USP46 (show USP46 ELISA Kits), respectively. Both complexes contain the UAF1 (show WDR48 ELISA Kits) protein as a bona fide subunit. Interestingly, UAF1 (show WDR48 ELISA Kits)

USP12 Antigen Profile

Antigen Summary

Deubiquitinating enzyme. Has almost no deubiquitinating activity by itself and requires the interaction with wdr48 to have a high activity (By similarity).

Gene names and symbols associated with USP12

  • ubiquitin specific peptidase 12 (usp12) antibody
  • ubiquitin specific peptidase 12 (USP12) antibody
  • Ubiquitin carboxyl-terminal hydrolase 12 (ubp12) antibody
  • ubiquitin specific peptidase 12 (Usp12) antibody
  • ubiquitin specific peptidase 12 (usp12-a) antibody
  • ubiquitin specific peptidase 12 pseudogene 1 (USP12P1) antibody
  • ubiquitin specific peptidase 12a (usp12a) antibody
  • hapln3 antibody
  • sb:eu882 antibody
  • UBH1 antibody
  • USP12 antibody
  • USP12L1 antibody
  • USP12P1 antibody
  • wu:fi09d12 antibody

Protein level used designations for USP12

ubiquitin thiolesterase 12 , hyaluronan and proteoglycan link protein 3 , ubiquitin specific peptidase 12 , ubiquitin specific peptidase 12 pseudogene 1 , Deubiquitinating enzyme 12 , Ubiquitin thioesterase 12 , Ubiquitin-specific-processing protease 12 , ubiquitin carboxyl-terminal hydrolase 12 , deubiquitinating enzyme 12 , ubiquitin hydrolyzing enzyme 1 , ubiquitin specific protease 12 , ubiquitin thioesterase 12 , ubiquitin-hydrolyzing enzyme 1 , ubiquitin-specific-processing protease 12 , Deubiquitinating enzyme 12-A , Ubiquitin thioesterase 12-A , Ubiquitin-specific-processing protease 12-A , ubiquitin carboxyl-terminal hydrolase 12-A , ubiquitin thiolesterase 12-A , ubiquitin-specific protease 12-like 1 , ubiquitin specific protease 12 like 1 , deubiquitinating enzyme 12A , ubiquitin carboxyl-terminal hydrolase 12A , ubiquitin thioesterase 12A , ubiquitin thiolesterase 12A , ubiquitin-specific-processing protease 12A

548802 Xenopus (Silurana) tropicalis
735835 Pan troglodytes
100511469 Sus scrofa
100194904 Salmo salar
22217 Mus musculus
734447 Xenopus laevis
428078 Gallus gallus
486033 Canis lupus familiaris
525655 Bos taurus
360763 Rattus norvegicus
219333 Homo sapiens
9959 Homo sapiens
565736 Danio rerio
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