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anti-Ubiquitin Specific Peptidase 14 (TRNA-Guanine Transglycosylase) (USP14) Antibodies

USP14 encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. Additionally we are shipping USP14 Proteins (13) and USP14 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
USP14 59025 Q9JMA1
USP14 9097 P54578
USP14 291796  
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Top anti-USP14 Antibodies at antibodies-online.com

Showing 10 out of 79 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB The anti-USP14 Pab (ABIN388902) is used in Western blot to detect USP14 in USP14-transfected HeLa cell lysates. Transfection data is kindly provided by Dr. B. Pierrat from the Novartis Institute for Biomedical Research (Basel, Switzerland). Western blot analysis of anti-USP14 Pab (ABIN388902) in A2058 cell line lysates (35 µg/lane). USP14 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB USP14 Antibody (C-term) (ABIN1881985) western blot analysis in A2058 cell line lysates (35 µg/lane). This demonstrates the USP14 antibody detected the USP14 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated WB USP14 Antibody (N-term) (ABIN1882288) western blot analysis in K562,Jurkat cell line,mouse brain abd rat brain tissue lysates (35 µg/lane). This demonstrates the USP14 antibody detected the USP14 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to USP14 on HeLa cell (antibody concentration 20 µg/mL). USP14 monoclonal antibody (M04), clone 6D6 Western Blot analysis of USP14 expression in HeLa. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated WB USP14 monoclonal antibody (M08), clone 1F8. Western Blot analysis of USP14 expression in Hela NE. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IF, ELISA, WB USP14 monoclonal antibody (M04), clone 6D6 Western Blot analysis of USP14 expression in HeLa . Immunofluorescence of monoclonal antibody to USP14 on HeLa cell. [antibody concentration 20 ug/ml] 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: A431 , 10% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Mouse Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$537.17
Details
Human Mouse Un-conjugated WB   400 μL Log in to see 8 to 10 Days
$463.83
Details

USP14 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,
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Top referenced anti-USP14 Antibodies

  1. Human Polyclonal USP14 Primary Antibody for WB - ABIN1881985 : Chen, Qin, Li, Walters, Wilson, Mei, Wilson: The proteasome-associated deubiquitinating enzyme Usp14 is essential for the maintenance of synaptic ubiquitin levels and the development of neuromuscular junctions. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2009 (PubMed)
    Show all 6 references for ABIN1881985

  2. Human Monoclonal USP14 Primary Antibody for IF, WB - ABIN393858 : Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: New genetic associations detected in a host response study to hepatitis B vaccine. in Genes and immunity 2010 (PubMed)
    Show all 5 references for ABIN393858

  3. Human Monoclonal USP14 Primary Antibody for WB - ABIN393524 : Sowa, Bennett, Gygi, Harper: Defining the human deubiquitinating enzyme interaction landscape. in Cell 2009 (PubMed)
    Show all 5 references for ABIN393524

  4. Human Monoclonal USP14 Primary Antibody for WB - ABIN1882288 : Reuter, Medhurst, Waisfisz, Zhi, Herterich, Hoehn, Gross, Joenje, Hoatlin, Mathew, Huber: Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport. in Experimental cell research 2003 (PubMed)
    Show all 3 references for ABIN1882288

  5. Human Monoclonal USP14 Primary Antibody for IF, ELISA - ABIN563939 : Hyrskyluoto, Bruelle, Lundh, Do, Kivinen, Rappou, Reijonen, Waltimo, Petersén, Lindholm, Korhonen: Ubiquitin-specific protease-14 reduces cellular aggregates and protects against mutant huntingtin-induced cell degeneration: involvement of the proteasome and ER stress-activated kinase IRE1?. in Human molecular genetics 2014 (PubMed)

  6. Human Polyclonal USP14 Primary Antibody for IHC (p), WB - ABIN388902 : Mines, Goodwin, Limbird, Cui, Fan: Deubiquitination of CXCR4 by USP14 is critical for both CXCL12-induced CXCR4 degradation and chemotaxis but not ERK ativation. in The Journal of biological chemistry 2009 (PubMed)

More Antibodies against USP14 Interaction Partners

Mouse (Murine) Ubiquitin Specific Peptidase 14 (TRNA-Guanine Transglycosylase) (USP14) interaction partners

  1. USP14's catalytic activity is required for nervous system structure and function and has an ongoing role in NMJ synaptic transmission. USP14 regulation of the ubiquitination status of protein kinases, coordinates NMJ intracellular signaling pathways.

  2. Overexpression of the Usp14 reduces cellular aggregates in mutant Htt-expressing cells mainly via the ubiquitin proteasome system.

  3. USP14 modulates hippocampal short-term plasticity and vesicle number independent of its deubiquitinating activity.

  4. Differences in genetic background were shown to affect ubiquitin expression and dramatically alter the phenotypes caused by USP14 deficiency.

  5. Data indicate that increased levels of phosphorylated tau correlated with the onset of axonal varicosities in the ubiquitin-specific protease 14 (Usp14)-deficient mice.

  6. miR (show MLXIP Antibodies)-124 promotes neuronal survival under ischemic conditions via Usp14-dependent REST degradation.

  7. overexpression of HA-USP14 increased TNFalph (show TLR4 Antibodies)a

  8. Oxidative stress increasd USP14 expression, and beta-carotene dose-dependently inhibited increased expression in mouse skeletal muscle myotubes.

  9. ubiquitinated loosely folded proteins, after becoming bound to the 26 S, interact with Ubp6/Usp14 or Uch37 (show UCHL5 Antibodies) to activate ATP hydrolysis and enhance their own destruction

  10. USP14 has a role in regulating synaptic activity in mammals

Human Ubiquitin Specific Peptidase 14 (TRNA-Guanine Transglycosylase) (USP14) interaction partners

  1. Increased USP14 expression in patients with breast cancer was associated with a poorer prognosis.

  2. Akt (show AKT1 Antibodies)-mediated phosphorylation of USP14 at Ser432, which normally blocks its catalytic site in the inactive conformation, activates its deubiquitinating activity in vitro and in cells.

  3. our findings suggested that USP14 is involved in the progression of hepatocellular carcinoma(HCC (show FAM126A Antibodies)) and may be a useful therapeutic target in HCC (show FAM126A Antibodies)

  4. Cell surface ubiquitination precedes endocytosis, after which USP14 acts as an ubiquitin-binding protein that targets the ubiquitinated GABA B receptor to lysosomal degradation and promotes its deubiquitination.

  5. USP14 shows a marked preference for ubiquitin-cyclin B conjugates that carry more than one ubiquitin modification or chain

  6. our findings suggest that USP14 is involved in the progression of epithelial ovarian cancer

  7. Downregulation of USP14 expression arrested the cell cycle, which may be related to beta-catenin (show CTNNB1 Antibodies) degradation.

  8. MiR (show MLXIP Antibodies)-4782-3p inhibited cell proliferation in NSCLC by targeting USP14, ZEB2 (show ZEB2 Antibodies) and XIAP (show XIAP Antibodies).

  9. b-AP15 is an inhibitor of deubiquitylating enzyme USP14 and UCHL5 (show UCHL5 Antibodies) induces apoptosis in multiple myeloma and overcomes bortezomib resistance.

  10. overexpression of HA-USP14 increased the LPS (show IRF6 Antibodies)-, TNFalpha (show TNF Antibodies)-, or Escherichia coli-induced IL-8 (show IL8 Antibodies) release in human lung epithelial cells.

USP14 Antigen Profile

Protein Summary

This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with USP14

  • ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) (USP14) antibody
  • ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) (usp14) antibody
  • universal stress protein (usp14) antibody
  • peptidase C19 family protein (usp14) antibody
  • Protein USP-14 (usp-14) antibody
  • ubiquitin specific peptidase 14 (Usp14) antibody
  • ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) (Usp14) antibody
  • 2610005K12Rik antibody
  • 2610037B11Rik antibody
  • AW107924 antibody
  • ax antibody
  • C78769 antibody
  • DDBDRAFT_0202821 antibody
  • DDBDRAFT_0237695 antibody
  • DDB_0202821 antibody
  • DDB_0237695 antibody
  • MGC69343 antibody
  • MGC81945 antibody
  • TGT antibody
  • USP14 antibody

Protein level used designations for USP14

ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) , ubiquitin specific protease 14 (tRNA-guanine transglycosylase) , universal stress protein , ubiquitin domain-containing protein , ubiquitin carboxyl-terminal hydrolase 14-like , ataxia , dUB-type TGT for deubiquitinating enzyme , deubiquitinating enzyme 14 , ubiquitin carboxyl-terminal hydrolase 14 , ubiquitin specific protease 14 , ubiquitin thioesterase 14 , ubiquitin thiolesterase 14 , ubiquitin-specific-processing protease 14 , tRNA-guanine transglycosylase, 60-kD subunit , ubiquitin-specific processing protease 14 , queuine tRNA-ribosyltransferase

GENE ID SPECIES
100090009 Ornithorhynchus anatinus
421063 Gallus gallus
447733 Xenopus laevis
448110 Xenopus (Silurana) tropicalis
480182 Canis lupus familiaris
698087 Macaca mulatta
3130489 Haloarcula marismortui ATCC 43049
8617881 Dictyostelium discoideum AX4
100013535 Monodelphis domestica
100394297 Callithrix jacchus
100473541 Ailuropoda melanoleuca
100586916 Nomascus leucogenys
175105 Caenorhabditis elegans
59025 Mus musculus
505106 Bos taurus
9097 Homo sapiens
291796 Rattus norvegicus
100009078 Oryctolagus cuniculus
455325 Pan troglodytes
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