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Ubiquitin Specific Peptidase 16 Proteins (USP16)

USP16 encodes a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase/anaphase transition. Additionally we are shipping USP16 Antibodies (93) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
USP16 10600 Q9Y5T5
Mouse USP16 USP16 74112 Q99LG0
Rat USP16 USP16 288306 Q2KJ09
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Top USP16 Proteins at

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 39 to 44 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days

USP16 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,

Top referenced USP16 Proteins

  1. Human USP16 Protein expressed in Wheat germ - ABIN1324758 : Frangini, Sjöberg, Roman-Trufero, Dharmalingam, Haberle, Bartke, Lenhard, Malumbres, Vidal, Dillon: The aurora B kinase and the polycomb protein ring1B combine to regulate active promoters in quiescent lymphocytes. in Molecular cell 2013 (PubMed)

More Proteins for Ubiquitin Specific Peptidase 16 (USP16) Interaction Partners

Human Ubiquitin Specific Peptidase 16 (USP16) interaction partners

  1. The data unveil a unique mechanism by which Usp16 promotes the localization and maintenance of Plk1 on the kinetochores for proper chromosome alignment.

  2. Data show that histone H2A deubiquitinase USP16 interacts with E3 ubiquitin-protein ligase HERC2, negatively regulates DNA damage-induced ubiquitin foci formation, and is required for termination of the ubiquitin signal.

  3. S552P disrupts the interaction between Ubp-M and nuclear export protein CRM1, increasing Ubp-M nuclear retention as cells progress into M phase, revealing a critical function for Ubp-M S552P.

  4. in human tissues overexpression of USP16 reduces the expansion of normal fibroblasts and postnatal neural progenitors, whereas downregulation of USP16 partially rescues the proliferation defects of Down's syndrome fibroblasts

  5. Study reports the solution structure of the BUZ domain of Ubp-M, a ubiquitin-specific protease, and its interaction with ubiquitin; the Ubp-M BUZ domain features three zinc-binding sites consisting of 12 residues.

  6. knockdown of Ubp-M in HeLa cells results in slow cell growth rates owing to defects in the mitotic phase of the cell cycle

  7. a new cryptic USP16-RUNX1 (show RUNX1 Proteins) fusion in chronic myelomonocytic leukemia

Mouse (Murine) Ubiquitin Specific Peptidase 16 (USP16) interaction partners

  1. these studies identified Usp16 (show USP21 Proteins) as one of the histone H2A deubiquitinases, which coordinates with the H2A ubiquitin ligase (show RNF123 Proteins) PRC1 (show PRC1 Proteins) to regulate hematopoiesis, and revealed cell cycle regulation by Usp16 (show USP21 Proteins) as key for HSC (show FUT1 Proteins) differentiation.

  2. study identifies Usp16 and H2A deubiquitination as critical regulators of ESC gene expression and differentiation

  3. results suggest that USP16 (show USP21 Proteins) has an important role in antagonizing the self-renewal and/or senescence pathways in Down's syndrome and could serve as an attractive target to ameliorate some of the associated pathologies

USP16 Protein Profile

Protein Summary

This gene encodes a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase/anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant form of the protein was shown to block cell division. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with USP16

  • universal stress protein (usp16)
  • ubiquitin specific peptidase 16 (USP16)
  • ubiquitin specific peptidase 16 (usp16)
  • ubiquitin specific peptidase 16 (Usp16)
  • ubiquitin specific protease 16 (usp16)
  • 1200004E02Rik protein
  • 2810483I07Rik protein
  • 6330514E22Rik protein
  • si:ch211-238e22.5 protein
  • si:dkey-121n8.2 protein
  • UBP-M protein
  • UBPM protein
  • USP16 protein
  • wu:fc76b02 protein
  • wu:fc76b08 protein

Protein level used designations for USP16

universal stress protein , ubiquitin specific peptidase 16 , Deubiquitinating enzyme 16 , Ubiquitin thioesterase 16 , Ubiquitin-specific-processing protease 16 , ubiquitin carboxyl-terminal hydrolase 16 , ubiquitin thiolesterase 16 , ubiquitin specific protease 16 , deubiquitinating enzyme 16 , ubiquitin thioesterase 16 , ubiquitin-specific-processing protease 16 , ubiquitin-processing protease UBP-M , ubiquitin-specific processing protease 16

3128725 Haloarcula marismortui ATCC 43049
100020904 Monodelphis domestica
418485 Gallus gallus
447956 Xenopus (Silurana) tropicalis
458497 Pan troglodytes
706403 Macaca mulatta
100353041 Oryctolagus cuniculus
519992 Bos taurus
10600 Homo sapiens
478398 Canis lupus familiaris
74112 Mus musculus
288306 Rattus norvegicus
398823 Xenopus laevis
569700 Danio rerio
Selected quality suppliers for USP16 Proteins (USP16)
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