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Ubiquitin Specific Peptidase 22 (USP22) ELISA Kits

Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Additionally we are shipping USP22 Antibodies (71) and USP22 Proteins (2) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human USP22 USP22 23326 Q9UPT9
Anti-Mouse USP22 USP22 216825 Q5DU02
Anti-Rat USP22 USP22 303201  
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More ELISA Kits for USP22 Interaction Partners

Fruit Fly (Drosophila melanogaster) Ubiquitin Specific Peptidase 22 (USP22) interaction partners

  1. Loss of Ataxin-7 (show ATXN7 ELISA Kits) results in a toxic gain of activity of the Non-stop deubiquitinase.

  2. Data establish that Nonstop actually functions as an ubiquitin (show UBA52 ELISA Kits) protease to control the levels of ubiquitinated histone H2B in flies. We further establish that Nonstop is the functional homolog of yeast Ubp8

  3. 3 additional subunits of TFTC/STAGA (dSgf11, non-stop, & en(y)2) help form the deubiquitination module. This module is an enhancer of position effect variegation in Drosophila.

Human Ubiquitin Specific Peptidase 22 (USP22) interaction partners

  1. findings suggest that USP22 may be involved in hepatocellular carcinoma progression in cooperation with survivin (show BIRC5 ELISA Kits).

  2. These findings provide evidence that high USP22 expression might be important in tumor progression and serves as an independent molecular marker for poor hepatocellular carcinoma prognosis

  3. USP22 attenuated the invasion capacity of colon cancer cells by inhibiting the STAT3 (show STAT3 ELISA Kits)/MMP9 (show MMP9 ELISA Kits) signaling pathway.

  4. Our data indicated that USP22 may promote lung adenocarcinoma cell invasion by the induction of EMT (show ITK ELISA Kits).

  5. Data show that the aggregates formed by polyQ-expanded ataxin 7 (show ATXN7 ELISA Kits) sequester ubiquitin-specific protease (USP22) through specific interactions.

  6. the deubiquitinating enzyme activity of USP22 is necessary for regulating HeLa cell growth, and it promotes cell proliferation via the c-Myc (show MYC ELISA Kits)/cyclin D2 (show CCND2 ELISA Kits), BMI-1 (show BMI1 ELISA Kits) and p53 (show TP53 ELISA Kits) pathways in HeLa cells

  7. ShRNA-mediated silencing of the ubiquitin-specific protease 22 gene restrained cell progression and affected the Akt (show AKT1 ELISA Kits) pathway in nasopharyngeal carcinoma.

  8. Data indicate that ubiquitin specific peptidase 22 (USP22)-mediated sirtuin 1 (SIRT1 (show SIRT1 ELISA Kits)) deubiquitination inhibits STAT3 (show STAT3 ELISA Kits) transcription factor acetylation and its transcriptional activation.

  9. USP22 is overexpressed in human NSCLC tissues and cell lines. USP22 silencing downregulates MDMX protein (show MDM4 ELISA Kits) expression and activates the p53 (show TP53 ELISA Kits) pathway.

  10. Increased USP22 expression in colon cancer correlated with reduced uH2B expression, and this expression pattern may contribute to tumor progression.

Mouse (Murine) Ubiquitin Specific Peptidase 22 (USP22) interaction partners

  1. Usp22 deficiency impairs intestinal epithelial lineage specification.

  2. USP22 is a transcriptional repressor of the locus encoding the core pluripotency factor sex-determining region Y-box 2 (SOX2 (show SOX2 ELISA Kits)) in embryonic stem cells.

  3. Genetic deletion of the usp22 gene results in Sirt1 (show SIRT1 ELISA Kits) instability, elevated p53 (show TP53 ELISA Kits) transcriptional activity and early embryonic lethality.

USP22 Antigen Profile

Antigen Summary

Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators, where it is required for transcription (By similarity).

Gene names and symbols associated with USP22

  • ubiquitin specific peptidase 22 (USP22) antibody
  • ubiquitin specific peptidase 22 (usp22) antibody
  • non-stop (not) antibody
  • hypothetical LOC454511 (USP22) antibody
  • ubiquitin specific protease 22 (USP22) antibody
  • universal stress protein (usp22) antibody
  • ubiquitin specific peptidase 22 (Usp22) antibody
  • AI427806 antibody
  • anon-WO0257455.9 antibody
  • CG4166 antibody
  • Dmel\\CG4166 antibody
  • i155 antibody
  • l(3)02069 antibody
  • l(3)j9A6 antibody
  • nonstop antibody
  • NOT antibody
  • UBP8 antibody
  • Upb8 antibody
  • USP3L antibody
  • USP22 antibody
  • zgc:136342 antibody

Protein level used designations for USP22

ubiquitin specific peptidase 22 , ubiquitin thiolesterase 22 , ubiquitin carboxyl-terminal hydrolase 22-like , CG4166-PB , nonstop , not-PB , ubiquitin specific protease 22 , universal stress protein , deubiquitinating enzyme 22 , ubiquitin carboxyl-terminal hydrolase 22 , ubiquitin thioesterase 22 , ubiquitin-specific processing protease 22 , ubiquitin-specific-processing protease 22

712098 Macaca mulatta
100053238 Equus caballus
100340977 Oryctolagus cuniculus
100379835 Xenopus (Silurana) tropicalis
100456449 Pongo abelii
100476428 Ailuropoda melanoleuca
40030 Drosophila melanogaster
454511 Pan troglodytes
694018 Macaca mulatta
3129313 Haloarcula marismortui ATCC 43049
23326 Homo sapiens
216825 Mus musculus
692275 Danio rerio
509694 Bos taurus
303201 Rattus norvegicus
416501 Gallus gallus
609588 Canis lupus familiaris
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