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USP48 encodes a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Additionally we are shipping USP48 Antibodies (42) and USP48 Proteins (3) and many more products for this protein.
this study demonstrates that USP48 controls the Ubiquitin/proteasome-system-dependent turnover of activated NF-kappaB (show NFKB1 ELISA Kits)/RelA (show NFkBP65 ELISA Kits) in the nucleus.
Northern blot analysis revealed a single USP31 transcript of approximately 4 kb, which was primarily expressed in the testis and lung.
The Overexpression of USP31 in HEK (show EPHA3 ELISA Kits) 293T cells inhibited TNFalpha (show TNF ELISA Kits), CD40 (show CD40 ELISA Kits), LMP1 (show PDLIM7 ELISA Kits), TRAF2 (show TRAF2 ELISA Kits), TRAF6 (show TRAF6 ELISA Kits) and IKKbeta (show IKBKB ELISA Kits)-mediated NF-kappaB (show NFKB1 ELISA Kits) activation, but did not inhibit Smad (show SMAD1 ELISA Kits)-mediated transcription activation.
data demonstrate a crucial role for the dynamic interaction between D3R and USP48 in the regulation of NHE3 (show SLC9A3 ELISA Kits) expression and function
This gene encodes a protein containing domains that associate it with the peptidase family C19, also known as family 2 of ubiquitin carboxyl-terminal hydrolases. Family members function as deubiquitinating enzymes, recognizing and hydrolyzing the peptide bond at the C-terminal glycine of ubiquitin. Enzymes in peptidase family C19 are involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
deubiquitinating enzyme 48
, ubiquitin carboxyl-terminal hydrolase 48
, ubiquitin specific protease 31
, ubiquitin specific protease 48
, ubiquitin thioesterase 48
, ubiquitin thiolesterase 48
, ubiquitin-specific-processing protease 48
, synaptic ubiquitin-specific protease
, ubiquitin specific peptidase 48
, ubiquitin specific peptidase 31
, ubiquitin carboxyl-terminal hydrolase 31-like
, ubiquitin carboxyl-terminal hydrolase 48-like